Multiplexed perturbation of yew reveals cryptic proteins that enable a total biosynthesis of baccatin III and Taxol precursors DOI Creative Commons

Conor J. McClune,

Chun‐Ting Liu, Chloe Wick

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Ноя. 8, 2024

Plants make complex and potent therapeutic molecules, but difficulties in sourcing from natural producers or chemical synthesis can challenge their use the clinic. A prominent example is anti-cancer paclitaxel (Taxol

Язык: Английский

Multiplexed perturbation of yew reveals cryptic proteins that enable a total biosynthesis of baccatin III and Taxol precursors DOI Creative Commons

Conor J. McClune,

Chun‐Ting Liu, Chloe Wick

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Ноя. 8, 2024

Plants make complex and potent therapeutic molecules, but difficulties in sourcing from natural producers or chemical synthesis can challenge their use the clinic. A prominent example is anti-cancer paclitaxel (Taxol

Язык: Английский

Процитировано

3