Spotlight on “A protein blueprint of the diatom CO 2 -fixing organelle” by Nam et al. (2024) and “Diatom pyrenoids are encased in a protein shell that enables efficient CO 2 fixation” by Shimakawa et al. (2024) DOI Creative Commons

Weiyang Chen,

Dario Leister

Journal of Mitochondria Plastids and Endosymbiosis, Год журнала: 2024, Номер 3(1)

Опубликована: Дек. 24, 2024

Recent studies by Nam et al. and Shimakawa published in Cell (2024) have elucidated the protein composition of diatom pyrenoids constructing protein–protein interaction networks for centric Thalassiosira pseudonana using vivo photo-crosslinking with Rubisco pennate Phaeodactylum tricornutum. These investigations identified a family proteins that form pyrenoid sheath, termed "Shell" proteins. Knockout experiments revealed absence or malformation these sheaths leads to altered structures impaired growth under atmospheric CO2 conditions. The research highlights are enclosed lattice-like proteinaceous sheaths, as demonstrated through multiscale imaging techniques. findings provide insights into convergent evolution across various algal lineages suggest potential strategies engineering crop plants enhance agricultural yields.

Язык: Английский

Algal chloroplast pyrenoids: Evidence for convergent evolution DOI Creative Commons
Benedict M. Long, Yusuke Matsuda, James V. Moroney

и другие.

Proceedings of the National Academy of Sciences, Год журнала: 2024, Номер 121(14)

Опубликована: Март 21, 2024

Язык: Английский

Процитировано

6

Harnessing microalgae: Innovations for achieving UN Sustainable Development Goals and climate resilience DOI Creative Commons
Anees Ahmad, S. M. Ashraf

Journal of Water Process Engineering, Год журнала: 2024, Номер 68, С. 106506 - 106506

Опубликована: Ноя. 18, 2024

Язык: Английский

Процитировано

4

DiatOmicBase: a versatile gene‐centered platform for mining functional omics data in diatom research DOI Creative Commons
Émilie Villar, Nathanaël Zweig, Pierre Vincens

и другие.

The Plant Journal, Год журнала: 2025, Номер 121(6)

Опубликована: Март 1, 2025

SUMMARY Diatoms are prominent microalgae found in all aquatic environments. Over the last 20 years, thanks to availability of genomic and genetic resources, diatom species such as Phaeodactylum tricornutum Thalassiosira pseudonana have emerged valuable experimental model systems for exploring topics ranging from evolution cell biology, (eco)physiology, biotechnology. Since first genome sequencing projects initiated more than years ago, numerous genome‐enabled datasets been generated, based on RNA‐Seq proteomics experiments, epigenomes, ecotype variant analysis. Unfortunately, these generated by various laboratories, often disparate formats challenging access analyze. Here we present DiatOmicBase, a portal gathering comprehensive omics resources P. T. facilitate exploration dispersed public design new experiments prior‐art. DiatOmicBase provides gene annotations, transcriptomic profiles browser with variants, histone methylation marks, transposable elements, non‐coding RNAs, read densities experiments. We developed semi‐automatically updated module explore both publicly available users' private datasets. Using gene‐level expression data, users can perform exploratory data analysis, differential expression, pathway biclustering, co‐expression network Users create heatmaps visualize pre‐computed comparisons selected subsets. Automatic other bioinformatic tools comparative functional genomics is also provided. Focusing currently centralized , showcase several examples how strengthens molecular research diatoms, making organisms accessible broad community.

Язык: Английский

Процитировано

0

Multiphase CO2-dependent photosynthesis in marine diatoms DOI Creative Commons
Ginga Shimakawa, Yusuke Matsuda

Frontiers in Photobiology, Год журнала: 2025, Номер 3

Опубликована: Апрель 2, 2025

Diatoms, one of the most ubiquitous phytoplankton in oceans, have evolved a pyrenoid-based CO 2 -concentrating mechanism (CCM) to utilize limited seawater for photosynthesis. Recent proteomics analyses and molecular biological tools deepened our understanding mechanisms involved diatom chloroplast architecture CCM. Here, we provide an update knowledge processes high affinity photosynthesis dissolved inorganic carbon (DIC) diatoms. Based on phenotype genome-edited mutants, propose model CCM composed four phases -dependent at (I) less than 0.1 mM, (II) 0.1–2 (III) 2–10 (IV) more 10 mM DIC concentrations, which rate-determining steps are capture unfixed stroma Phases I II, evolution pyrenoid-penetrating thylakoid lumen Phase III, transport IV. Under natural containing mainly form HCO 3 − , marine diatoms is likely primarily shifting II when available limited.

Язык: Английский

Процитировано

0

Genetic engineering in diatoms: advances and prospects DOI Creative Commons
Yixuan Li,

Longji Deng,

E. Walker

и другие.

The Plant Journal, Год журнала: 2025, Номер 121(6)

Опубликована: Март 1, 2025

SUMMARY Diatoms are among the most diverse and ecologically significant groups of photosynthetic microalgae, contributing over 20% global primary productivity. Their ecological significance, unique biology, genetic tractability make them ideal targets for genomic engineering metabolic reprogramming. Over past few decades, numerous methods have been developed applied to these organisms better understand function individual genes how they underpin diatom metabolism. Additionally, ability diatoms synthesize high‐value metabolites elaborate mineral structures offers potential applications in biotechnology, including synthesis novel pharmaceuticals, nutraceuticals, biomaterials. This review discusses latest developments provides prospects not only promote use fields biotechnology but also deepen our understanding their role natural ecosystems.

Язык: Английский

Процитировано

0

Engineering microbial cell factories by multiplexed spatiotemporal control of cellular metabolism: Advances, challenges, and future perspectives DOI

Wenwen Yu,

Ke Jin, Xianhao Xu

и другие.

Biotechnology Advances, Год журнала: 2024, Номер 79, С. 108497 - 108497

Опубликована: Дек. 5, 2024

Язык: Английский

Процитировано

1

From algae to plants: understanding pyrenoid-based CO2-concentrating mechanisms DOI Creative Commons
Ella Catherall, Sabina Musiał, Nicky Atkinson

и другие.

Trends in Biochemical Sciences, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

0

Spotlight on “A protein blueprint of the diatom CO 2 -fixing organelle” by Nam et al. (2024) and “Diatom pyrenoids are encased in a protein shell that enables efficient CO 2 fixation” by Shimakawa et al. (2024) DOI Creative Commons

Weiyang Chen,

Dario Leister

Journal of Mitochondria Plastids and Endosymbiosis, Год журнала: 2024, Номер 3(1)

Опубликована: Дек. 24, 2024

Recent studies by Nam et al. and Shimakawa published in Cell (2024) have elucidated the protein composition of diatom pyrenoids constructing protein–protein interaction networks for centric Thalassiosira pseudonana using vivo photo-crosslinking with Rubisco pennate Phaeodactylum tricornutum. These investigations identified a family proteins that form pyrenoid sheath, termed "Shell" proteins. Knockout experiments revealed absence or malformation these sheaths leads to altered structures impaired growth under atmospheric CO2 conditions. The research highlights are enclosed lattice-like proteinaceous sheaths, as demonstrated through multiscale imaging techniques. findings provide insights into convergent evolution across various algal lineages suggest potential strategies engineering crop plants enhance agricultural yields.

Язык: Английский

Процитировано

0