Crass-Like Phages are Suitable Indicators of Antibiotic Resistance Genes Found in Abundance in Fecally Polluted Samples DOI

Sara Morales-Cortés,

Laura Sala‐Comorera, Clara Gómez-Gómez

и другие.

Опубликована: Янв. 1, 2024

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Язык: Английский

Using A Harmonised Study Design and Quantitative Toolbox Reveals Major Inconsistencies When Investigating the Main Drivers of Water and Biofilm Antibiotic Resistomes in Different Rivers DOI Creative Commons

Melanie Leopold,

Claudia Kolm, Rita Linke

и другие.

Journal of Hazardous Materials, Год журнала: 2025, Номер unknown, С. 137343 - 137343

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Distribution status and influencing factors of antibiotic resistance genes in the Chaohu Lake, China DOI Creative Commons
Yan Zhang,

Guoao Ding,

Yue Gao

и другие.

PeerJ, Год журнала: 2025, Номер 13, С. e19384 - e19384

Опубликована: Апрель 25, 2025

Background Chaohu Lake (CL) is one of the most polluted areas in China due to its high content antibiotics. However, distribution and influencing factors antibiotic resistance genes (ARGs) this lake are still controversial. Methods To solve problem, we used metagenomic sequencing investigate in-fluencing ARGs CL. Results Our findings revealed existence nine kinds ARGs, including 45 specific genes. The abundant types were multidrug, bacitracin, polymyxin, macrolide lincosamide streptogramin, aminoglycoside. Multiple microorganisms undeniable ARG reservoirs, although they not dominant species microbiota. results also showed that both microbiota physiochemical played important roles shaping distributions Specifically, levels PO4-P (0.5927) total phosphorus (0.4971) had a greater impact than nitrogen (0.0515), NO 3- N (0.0352), NO2-N (−0.1975), NH3-N (−0.0952). Conclusions These provide valuable insights into lakes.

Язык: Английский

Процитировано

0

Intra- and extracellular DNA as carriers of antibiotic resistance genes and class 1 integrons in river waters DOI Creative Commons
Raffaella Sabatino, Periyasamy Sivalingam, Francesco Di Nezio

и другие.

Hydrobiologia, Год журнала: 2025, Номер unknown

Опубликована: Июнь 4, 2025

Язык: Английский

Процитировано

0

CrAss-like phages are suitable indicators of antibiotic resistance genes found in abundance in fecally polluted samples DOI Creative Commons

Sara Morales-Cortés,

Laura Sala‐Comorera, Clara Gómez-Gómez

и другие.

Environmental Pollution, Год журнала: 2024, Номер 359, С. 124713 - 124713

Опубликована: Авг. 10, 2024

Antibiotic resistance genes (ARGs) have been extensively observed in bacterial DNA, and more recently, phage particles from various water sources food items. The pivotal role played by ARG transmission the proliferation of antibiotic emergence new resistant strains calls for a thorough understanding underlying mechanisms. aim this study was to assess suitability prototypical p-crAssphage, proposed indicator human fecal contamination, recently isolated crAssBcn phages, both belonging Crassvirales group, as potential indicators ARGs. These crAss-like phages were evaluated alongside specific ARGs (bla

Язык: Английский

Процитировано

3

Arsenic Contamination in Sludge and Sediment and Relationship with Microbial Resistance Genes: Interactions and Remediation DOI Open Access

Menglong Xing,

Dajiang Yan,

Mengmeng Hai

и другие.

Water, Год журнала: 2024, Номер 16(24), С. 3633 - 3633

Опубликована: Дек. 17, 2024

Arsenic contamination in sludge and sediment has emerged as a pressing environmental issue with far-reaching implications. This review delves into the multifaceted problem of arsenic contamination, focusing on its complex interactions microbial resistance genes (MRGs). It explores key role microorganisms biogeochemical cycling arsenic, including processes such reduction, oxidation, methylation, volatilization. describes how resist through that encode proteins efflux pumps, enzymatic detoxification, intracellular sequestration. Arsenic, naturally occurring element, can enter various natural anthropogenic pathways, leading to detrimental effects quality. Understanding mobilization, transformation, their ability toxicity MRGs is essential for effective mitigation remediation strategies. discusses sources distribution sediment, intricate mechanisms resistance, potential implications management human health. also examines current research trends identifies areas requiring further investigation. By unraveling interplay between microorganisms, MRGs, this aims contribute deeper understanding guide future protection efforts.

Язык: Английский

Процитировано

3

Bacteriophages limitedly contribute to the antimicrobial resistome of microbial communities in wastewater treatment plants DOI Creative Commons
Raffaella Sabatino, Tomasa Sbaffi, Periyasamy Sivalingam

и другие.

Microbiology Spectrum, Год журнала: 2023, Номер 11(5)

Опубликована: Сен. 19, 2023

Bacteriophages are known as players in the transmission of antimicrobial resistance genes (ARGs) by horizontal gene transfer. In this study, we characterized bacteriophage community and associated ARGs to estimate potential for phages spread aquatic ecosystems analyzing intra- extracellular DNA isolated from two wastewater treatment plants (WWTPs) shotgun metagenomics. We compared phage resistome with bacterial investigated effect final disinfection on its resistome. Phage was mainly composed

Язык: Английский

Процитировано

7

Unveiling novel threats: Urban river isolation of Aeromonas veronii with unusual VEB-28 extended-spectrum β-lactamase and distinct mcr variants DOI
Fernanda Fernandes Santos, Tiago Barcelos Valiatti,

André Valêncio

и другие.

Chemosphere, Год журнала: 2024, Номер 357, С. 141918 - 141918

Опубликована: Апрель 11, 2024

Язык: Английский

Процитировано

2

Disentangling abiotic and biotic effects of treated wastewater on stream biofilm resistomes enables the discovery of a new planctomycete beta-lactamase DOI Creative Commons
Mustafa Attrah,

Milo R. Schärer,

Mauro Esposito

и другие.

Microbiome, Год журнала: 2024, Номер 12(1)

Опубликована: Сен. 6, 2024

Язык: Английский

Процитировано

2

Towards the definition of an antibiotic resistome signature in wastewater and downstream environments DOI Creative Commons
Diogo Cachetas, Ivone Vaz‐Moreira, Vítor Pereira

и другие.

Environmental Pollution, Год журнала: 2024, Номер 357, С. 124424 - 124424

Опубликована: Июнь 21, 2024

Domestic wastewater is a significant reservoir of antibiotic resistance genes, which pose environmental and public health risks. We aimed to define an resistome signature, represented by core i.e., shared ≥ 90% the metagenomes each three conceptual compartments - (influent, sludge, effluent), freshwater, agricultural soil. The definition signatures would support proposal framework for monitoring treatment efficacy assessing impact treated discharge into environment, such as freshwater Metagenomic data from 163 samples originating (n = 81), 58), soils 24) across different regions (29 countries, 5 continents), were analysed regarding diversity, based on annotation against database that merged CARD ResFinder databases. relative abundance total genes (corresponding ratio between reads number) was not statistically raw wastewater, being significantly higher than in or soils. latter had lowest genes. Genes conferring aminoglycosides, beta-lactams, tetracyclines among most abundant environments, while multidrug equally distributed all environments. signature included 27 detected at least resistomes, frequent soil resistomes. Among these responsible 8), macrolide-lincosamide-streptogramin B 7), aminoglycosides 4), beta-lactams 3), 2), sulphonamides polypeptides 1). This comprehensive assessment provides valuable insights dynamics urban systems their potential ecological implications diverse settings. Furthermore, guidance implementation One Health approaches.

Язык: Английский

Процитировано

1

The diversity of the antimicrobial resistome of lake Tanganyika increases with the water depth DOI
Raffaella Sabatino, Tomasa Sbaffi, Gianluca Corno

и другие.

Environmental Pollution, Год журнала: 2023, Номер 342, С. 123065 - 123065

Опубликована: Дек. 1, 2023

Язык: Английский

Процитировано

3