Published: Jan. 1, 2024
Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI
Language: Английский
FEMS Microbiology Ecology, Journal Year: 2024, Volume and Issue: 100(4)
Published: Feb. 22, 2024
Abstract Antibiotic resistance genes (ARGs) are abundant in aquatic ecosystems affected by human activities. Understanding the fate of ARGs across different is essential because significant role environments play cycle antibiotic resistance. We quantified selected Lake Maggiore, its main tributaries, and effluent wastewater treatment plant (WWTP) discharging directly into lake. linked their dynamics to anthropogenic impacts each tributary's watershed. The tetA lake were influenced those rivers WWTP effluent, concentration N-NH4, related pollution, while sul2 abundance was not any water inflow. varied rivers. Rivers with watersheds characterized high population density, touristic activities, secondary industries released more ARGs, ermB correlated higher numbers primary industries. This study suggests a limited contribution treated spread indicating as prevalent origin other sources calling for reconsideration on what considered major environment.
Language: Английский
Citations
3
Water Research, Journal Year: 2024, Volume and Issue: 264, P. 122208 - 122208
Published: Aug. 4, 2024
Language: Английский
Citations
3
Environmental Pollution, Journal Year: 2024, Volume and Issue: 359, P. 124713 - 124713
Published: Aug. 10, 2024
Antibiotic resistance genes (ARGs) have been extensively observed in bacterial DNA, and more recently, phage particles from various water sources food items. The pivotal role played by ARG transmission the proliferation of antibiotic emergence new resistant strains calls for a thorough understanding underlying mechanisms. aim this study was to assess suitability prototypical p-crAssphage, proposed indicator human fecal contamination, recently isolated crAssBcn phages, both belonging Crassvirales group, as potential indicators ARGs. These crAss-like phages were evaluated alongside specific ARGs (bla
Language: Английский
Citations
3
Microbiology Spectrum, Journal Year: 2023, Volume and Issue: 11(5)
Published: Sept. 19, 2023
Bacteriophages are known as players in the transmission of antimicrobial resistance genes (ARGs) by horizontal gene transfer. In this study, we characterized bacteriophage community and associated ARGs to estimate potential for phages spread aquatic ecosystems analyzing intra- extracellular DNA isolated from two wastewater treatment plants (WWTPs) shotgun metagenomics. We compared phage resistome with bacterial investigated effect final disinfection on its resistome. Phage was mainly composed
Language: Английский
Citations
7
Chemosphere, Journal Year: 2024, Volume and Issue: 357, P. 141918 - 141918
Published: April 11, 2024
Language: Английский
Citations
2
Microbiome, Journal Year: 2024, Volume and Issue: 12(1)
Published: Sept. 6, 2024
Language: Английский
Citations
2
Water, Journal Year: 2024, Volume and Issue: 16(24), P. 3633 - 3633
Published: Dec. 17, 2024
Arsenic contamination in sludge and sediment has emerged as a pressing environmental issue with far-reaching implications. This review delves into the multifaceted problem of arsenic contamination, focusing on its complex interactions microbial resistance genes (MRGs). It explores key role microorganisms biogeochemical cycling arsenic, including processes such reduction, oxidation, methylation, volatilization. describes how resist through that encode proteins efflux pumps, enzymatic detoxification, intracellular sequestration. Arsenic, naturally occurring element, can enter various natural anthropogenic pathways, leading to detrimental effects quality. Understanding mobilization, transformation, their ability toxicity MRGs is essential for effective mitigation remediation strategies. discusses sources distribution sediment, intricate mechanisms resistance, potential implications management human health. also examines current research trends identifies areas requiring further investigation. By unraveling interplay between microorganisms, MRGs, this aims contribute deeper understanding guide future protection efforts.
Language: Английский
Citations
2
Environmental Pollution, Journal Year: 2024, Volume and Issue: 357, P. 124424 - 124424
Published: June 21, 2024
Domestic wastewater is a significant reservoir of antibiotic resistance genes, which pose environmental and public health risks. We aimed to define an resistome signature, represented by core i.e., shared ≥ 90% the metagenomes each three conceptual compartments - (influent, sludge, effluent), freshwater, agricultural soil. The definition signatures would support proposal framework for monitoring treatment efficacy assessing impact treated discharge into environment, such as freshwater Metagenomic data from 163 samples originating (n = 81), 58), soils 24) across different regions (29 countries, 5 continents), were analysed regarding diversity, based on annotation against database that merged CARD ResFinder databases. relative abundance total genes (corresponding ratio between reads number) was not statistically raw wastewater, being significantly higher than in or soils. latter had lowest genes. Genes conferring aminoglycosides, beta-lactams, tetracyclines among most abundant environments, while multidrug equally distributed all environments. signature included 27 detected at least resistomes, frequent soil resistomes. Among these responsible 8), macrolide-lincosamide-streptogramin B 7), aminoglycosides 4), beta-lactams 3), 2), sulphonamides polypeptides 1). This comprehensive assessment provides valuable insights dynamics urban systems their potential ecological implications diverse settings. Furthermore, guidance implementation One Health approaches.
Language: Английский
Citations
1
Environmental Pollution, Journal Year: 2023, Volume and Issue: 342, P. 123065 - 123065
Published: Dec. 1, 2023
Language: Английский
Citations
3
bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown
Published: Nov. 20, 2023
Abstract Background Antibiotic resistance, which is mediated by environmental reservoirs, poses a threat to human and animal health. Aquatic biofilms impacted treated wastewater (WW) are known reservoirs for antibiotic however the specific influence of biotic factors abiotic from WW on abundance resistance genes (ARGs) within aquatic remains unclear. Additionally, experimental evidence limited as whether with low sequence similarity reference ARGs actually encode functional ARGs, particularly complex microbial communities. Results To disentangle effects ARG abundances, natural were previously grown in flume systems different proportions stream water either ultrafiltered or nonultrafiltered WW. In this study, we conducted deep shotgun metagenomic sequencing 75 biofilm, stream, samples these compared taxonomic microbiome resistome composition. Statistical analysis revealed an alignment composition significant association treatment. Several classes exhibited increase abundances increasing percentages contrast, sulfonamide BEL family beta-lactamase showed greater Overall, our results pointed toward dominance over determining WW-impacted suggested gene family-specific mechanisms divergent patterns. investigate one families experimentally, biochemically characterized new Planctomycetota ( Phycisphaeraceae ). This displayed activity cleavage cephalosporin analog despite sharing identity ARGs. Conclusions discovery planctomycete noteworthy, not only because it was first be phylum, but also detected standard homology-based tools. summary, study relative importance context discharge their impact both biofilms.
Language: Английский
Citations
2