Animal Models Informing the Role of the Microbiome and its Metabolites in Rheumatoid Arthritis DOI
Jing Li, Jing He, Kristine A. Kuhn

и другие.

Rheumatic Disease Clinics of North America, Год журнала: 2025, Номер 51(2), С. 325 - 346

Опубликована: Фев. 28, 2025

Язык: Английский

Fusobacterium nucleatum extracellular vesicles are enriched in colorectal cancer and facilitate bacterial adhesion DOI Creative Commons
Xin Zheng, Tao Gong, Wanyi Luo

и другие.

Science Advances, Год журнала: 2024, Номер 10(38)

Опубликована: Сен. 20, 2024

Fusobacterium nucleatum in colorectal cancer (CRC) tissue is implicated at multiple stages of the disease, while mechanisms underlying bacterial translocation and colonization remain incompletely understood. Herein, we investigated whether extracellular vesicles derived from F. (FnEVs) have impacts on colonization. In mice with colitis-related CRC, a notable enrichment FnEVs was observed, leading to significant increase intratumor by accelerated progression CRC. The clinical CRC tissues demonstrated. Subsequently, revealed that undergo membrane fusion cells, transfer retention FomA recipient cell surfaces. Given its ability facilitate autoaggregation through interaction FN1441, presence surfaces presents target for adhesion. Collectively, findings unveil mechanism used EVs prepare niche conducive distal organs.

Язык: Английский

Процитировано

4
Oral Fusobacterium nucleatum resists the acidic pH of the stomach due to membrane erucic acid synthesized via enoyl-CoA hydratase-related protein FnFabM DOI Creative Commons
Xiaocong Li, Shipeng Zhang,

Hua-Fang Sheng

и другие.

Journal of Oral Microbiology, Год журнала: 2025, Номер 17(1)

Опубликована: Янв. 21, 2025

Background and Objective Oral bacteria can translocate to the intestine, their colonization efficiency is influenced by gastrointestinal tract pH. Understanding how oral resist acidic environments crucial for elucidating role in gut health disease.

Язык: Английский

Процитировано

0
NIAID workshop on infections and autoimmune diseases DOI

S E Ferguson,

Annette L. Rothermel,

Patricia Rohan

и другие.

Nature Immunology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 24, 2025

Язык: Английский

Процитировано

0
Association between sleep quality and serum biomarkers among long-term hot spring bathers: a cross-sectional study DOI
Yang Fen,

Yue Zou,

Yingying Zhang

и другие.

International Journal of Biometeorology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 27, 2025

Язык: Английский

Процитировано

0
Animal Models Informing the Role of the Microbiome and its Metabolites in Rheumatoid Arthritis DOI
Jing Li, Jing He, Kristine A. Kuhn

и другие.

Rheumatic Disease Clinics of North America, Год журнала: 2025, Номер 51(2), С. 325 - 346

Опубликована: Фев. 28, 2025

Язык: Английский

Процитировано

0