Journal of Controlled Release,
Год журнала:
2023,
Номер
358, С. 476 - 497
Опубликована: Май 15, 2023
Antiviral
peptides
and
antiviral
polysaccharides
can
play
a
major
role
in
the
prevention
treatment
of
emerging
viral
health
problems.
These
compounds
are
biocompatible,
environmentally
friendly,
non-toxic,
cost-effective,
yet
poorly
water
soluble
vulnerable
to
enzymatic
(protease)
degradation
within
aggressive
intercellular
microenvironment.
Therefore,
they
should
be
properly
protected
delivered
viruses
host
cells
by
well-designed
nanocarriers
that
mimic
terms
size,
morphology,
smart
function.
This
literature
review
is
meant
introduce
latest
advances
(mainly
past
five
years)
nano-assemblies
comprising
or
polysaccharides.
To
best
our
knowledge,
there
no
similar
study
has
solely
sufficiently
investigated
such
nanomaterials
partially
totally
derived
from
nature.
The
rational
classification
microorganism-,
plant-,
animal-derived
polysaccharide
peptide
delivering
exploration
their
relevant
applications
will
clarify
promising
capacity
these
state-of-the-art
materials
for
number
technologies
developed
inactivate
viruses.
Frontiers in Nanotechnology,
Год журнала:
2022,
Номер
4
Опубликована: Дек. 13, 2022
Nanoparticles
can
be
used
as
inhibitory
agents
against
various
microorganisms,
including
bacteria,
algae,
archaea,
fungi,
and
a
huge
class
of
viruses.
The
mechanism
action
includes
inhibiting
the
function
cell
membrane/stopping
synthesis
membrane,
disturbing
transduction
energy,
producing
toxic
reactive
oxygen
species
(ROS),
or
reducing
RNA
DNA
production.
Various
nanomaterials,
different
metallic,
silicon,
carbon-based
nanomaterials
nanoarchitectures,
have
been
successfully
Recent
research
strongly
agrees
that
these
nanoarchitecture-based
virucidal
materials
(nano-antivirals)
shown
activity
in
solid
state.
Therefore,
they
are
very
useful
development
several
products,
such
fabric
high-touch
surfaces.
This
review
thoroughly
critically
identifies
recently
developed
nano-antivirals
their
nano-antiviral
deposition
methods
on
substrates,
possible
mechanisms
action.
By
considering
commercial
viability
nano-antivirals,
recommendations
made
to
develop
scalable
sustainable
products
with
contact-killing
properties.
Expert Review of Anti-infective Therapy,
Год журнала:
2023,
Номер
21(4), С. 355 - 363
Опубликована: Фев. 14, 2023
The
inactivation
and
eradication
of
multidrug-resistant
bacteria,
fungi,
viruses
by
conventional
antibiotics
drugs
have
not
been
effective.
hindering
these
pathogens
in
hospital-acquired
infections
caused
Gram-positive
particularly
strains
S.
aureus
including
community-acquired
methicillin-resistant
(CA-MRSA)
MRSA
(HA-MRSA),
is
more
complicated,
specifically
patients
having
immunodeficiency
syndrome.Bare
functionalized
metal
oxide
nanoparticles
(NPs)
silver
(Ag)
NPs
shown
significant
antibacterial,
antifungal,
antiviral
activities.
Biosynthesis
AgNPs
fungal
species
media
cell-free
filtrate
culture
supernatant
can
provide
new
therapeutic
properties
compared
to
physical
chemical
methods.Various
primary
secondary
metabolites
fungi
such
as
phytochelatin,
trichodin,
primin,
altersolanol
A,
periconicin
brefeldin
graphislactone
phomol,
polysaccharides
(chitin,
glucans,
galactomannans),
enzymes
contribute
reducing
Ag+
ions
stabilizing
one-pot
method.
These
natural
compounds
augment
antimicrobial
activity
bypassing
multidrug-resistance
barriers
viruses,
fungi.
Controlling
physicochemical
effective
concentration
be
the
determinative
parameters
for
strength
AgNPs.
Therefore,
this
review,
we
tried
address
mechanisms
synthesized
Journal of Controlled Release,
Год журнала:
2023,
Номер
358, С. 476 - 497
Опубликована: Май 15, 2023
Antiviral
peptides
and
antiviral
polysaccharides
can
play
a
major
role
in
the
prevention
treatment
of
emerging
viral
health
problems.
These
compounds
are
biocompatible,
environmentally
friendly,
non-toxic,
cost-effective,
yet
poorly
water
soluble
vulnerable
to
enzymatic
(protease)
degradation
within
aggressive
intercellular
microenvironment.
Therefore,
they
should
be
properly
protected
delivered
viruses
host
cells
by
well-designed
nanocarriers
that
mimic
terms
size,
morphology,
smart
function.
This
literature
review
is
meant
introduce
latest
advances
(mainly
past
five
years)
nano-assemblies
comprising
or
polysaccharides.
To
best
our
knowledge,
there
no
similar
study
has
solely
sufficiently
investigated
such
nanomaterials
partially
totally
derived
from
nature.
The
rational
classification
microorganism-,
plant-,
animal-derived
polysaccharide
peptide
delivering
exploration
their
relevant
applications
will
clarify
promising
capacity
these
state-of-the-art
materials
for
number
technologies
developed
inactivate
viruses.
