Journal of Materials Chemistry B,
Год журнала:
2023,
Номер
12(4), С. 842 - 871
Опубликована: Дек. 5, 2023
Infectious
bone
defects
are
characterized
by
the
partial
loss
or
destruction
of
tissue
resulting
from
bacterial
contaminations
subsequent
to
diseases
external
injuries.
Traditional
transplantation
and
clinical
methods
insufficient
in
meeting
treatment
demands
for
such
diseases.
As
a
result,
researchers
have
increasingly
focused
on
development
more
sophisticated
biomaterials
improved
therapeutic
outcomes
recent
years.
This
review
endeavors
investigate
specific
reparative
materials
utilized
infectious
defects,
particularly
those
present
maxillofacial
region,
with
focus
capable
releasing
substances,
functional
contact
biomaterials,
novel
physical
therapy
materials.
These
operate
Bioactive Materials,
Год журнала:
2023,
Номер
27, С. 15 - 57
Опубликована: Март 27, 2023
Titanium
(Ti)
and
its
alloys
have
been
widely
used
as
orthopedic
implants,
because
of
their
favorable
mechanical
properties,
corrosion
resistance
biocompatibility.
Despite
significant
success
in
various
clinical
applications,
the
probability
failure,
degradation
revision
is
undesirably
high,
especially
for
patients
with
low
bone
density,
insufficient
quantity
or
osteoporosis,
which
renders
studies
on
surface
modification
Ti
still
active
to
further
improve
results.
It
discerned
that
physicochemical
properties
directly
influence
even
control
dynamic
interaction
subsequently
determines
rejection
implants.
Therefore,
it
crucial
endow
bulk
materials
specific
high
bioactivity
can
be
performed
by
realize
osseointegration.
This
article
first
reviews
characteristics
conventional
techniques
involving
mechanical,
physical
chemical
treatments
based
formation
mechanism
modified
coatings.
Such
methods
are
able
but
surfaces
static
state
cannot
respond
biological
cascades
from
living
cells
tissues.
Hence,
beyond
traditional
design,
responsive
avenues
then
emerging.
The
stimuli
sources
functionalization
originate
environmental
triggers
physiological
triggers.
In
short,
this
review
surveys
recent
developments
engineering
materials,
a
emphasis
advances
functionality,
provides
perspectives
improving
biocompatibility
Metals,
Год журнала:
2023,
Номер
13(7), С. 1299 - 1299
Опубликована: Июль 20, 2023
This
paper
presents
a
comprehensive
review
of
recent
advancements
in
surface
engineering
metals,
encompassing
techniques,
characterization
methods
and
applications.
The
study
emphasizes
the
significance
enhancing
performance
functionality
metallic
materials
various
industries.
discusses
different
techniques
employed
engineering,
including
physical
such
as
thermal
spray
coatings
chemical
electroplating.
It
also
explores
used
to
assess
microstructural,
topographical,
mechanical
properties
engineered
surfaces.
Furthermore,
highlights
field,
focusing
on
nanostructured
coatings,
modification
for
corrosion
protection,
biomedical
applications,
energy-related
functionalization.
improved
tribological
well
development
corrosion-resistant
bioactive
treatments
medical
implants.
applications
industries
aerospace,
automotive,
electronics,
healthcare
are
presented,
showcasing
use
enhance
components,
provide
wear
resistance,
improve
protection.
concludes
by
discussing
challenges
future
directions
highlighting
need
further
research
address
limitations
exploit
emerging
trends.
findings
this
contribute
advancing
understanding
its
sectors,
paving
way
innovations
advancements.
Journal of Magnesium and Alloys,
Год журнала:
2023,
Номер
11(9), С. 2999 - 3011
Опубликована: Сен. 1, 2023
Mg
and
its
alloys
have
been
introduced
as
promising
biodegradable
materials
for
biomedical
implant
applications
due
to
their
excellent
biocompatibility,
mechanical
behavior,
biodegradability.
However,
susceptibility
rapid
corrosion
within
the
body
poses
a
significant
challenge
restricts
applications.
To
overcome
this
issue,
various
surface
modification
techniques
developed
enhance
resistance
bioactivity
of
Mg-based
implants.
PEO
is
potent
technique
producing
an
oxide
film
on
that
significantly
minimizes
tendency
corrode.
inevitable
defects
discharges
poor
biological
activity
during
coating
process
remain
concern.
Therefore,
adding
suitable
particles
solution.
Hydroxyapatite
(HAp)
has
attracted
much
attention
in
development
scientific
community.
HAp
shows
biocompatibility
similarity
chemical
composition
mineral
portion
bone.
combination
with
implants
through
shown
improvements
bioactivity.
This
review
paper
provides
comprehensive
overview
recent
advances
preparation,
characterization,
behavior
by
PEO.
Hybrid Advances,
Год журнала:
2024,
Номер
5, С. 100151 - 100151
Опубликована: Фев. 9, 2024
Ti
and
Ti-based
alloys
are
increasingly
employed
as
components
for
various
industrial
applications,
both
structural
functional.
Forming
coatings
is
one
of
the
potentially
highly
effective
methods
to
shield
products
from
adverse
environmental
effects.
Among
numerous
techniques
forming
on
alloys,
plasma
electrolytic
oxidation
(PEO)
stands
out.
Coatings
produced
through
PEO
exhibit
high
resistance
corrosion,
substantial
wear,
strong
adhesion
substrate,
which
attributed
formation
chemical
bonds
between
underlying
material
coating.
Conversely,
may
not
provide
sufficient
protection
titanium
due
presence
porosity
fine
cracks.
Establishing
an
organic
film
coating
surface
a
potent
strategy
seal
defects,
thereby
inhibiting
intrusion
corrosive
elements
into
substrate.
Applying
polymer
layer
could
be
approach
manage
extent
damage
enhance
corrosion.
This
article
reviews
latest
developments
in
PEO/polymer
composite
investigates
corrosion
characteristics
these
coatings.
ACS Biomaterials Science & Engineering,
Год журнала:
2023,
Номер
9(8), С. 4442 - 4461
Опубликована: Июль 31, 2023
Dental
implants
have
become
the
mainstream
strategy
for
oral
restoration,
and
implant
materials
are
most
important
research
hot
spot
in
this
field.
So
far,
Ti
dominate
all
kinds
of
implants.
The
surface
properties
play
decisive
roles
osseointegration
antibacterial
performance.
Surface
modifications
can
significantly
change
micro/nanotopography
composition
implants,
which
will
effectively
improve
their
hydrophilicity,
mechanical
properties,
performance,
etc.
These
optimizations
thus
success
service
life.
In
paper,
latest
modification
techniques
dental
systematically
comprehensively
reviewed.
various
biomedical
functionalities
discussed
in-depth.
Finally,
a
profound
comment
on
challenges
opportunities
frontier
is
proposed,
promising
directions
future
were
explored.
ACS Biomaterials Science & Engineering,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 30, 2024
Titanium
and
its
alloys,
especially
Ti-6Al-4V,
are
widely
studied
in
implantology
for
their
favorable
characteristics.
However,
challenges
remain,
such
as
the
high
modulus
of
elasticity
concerns
about
cytotoxicity.
To
resolve
these
issues,
research
focuses
on
β-type
titanium
alloys
that
incorporate
elements
Mo,
Nb,
Sn,
Ta
to
improve
corrosion
resistance
obtain
a
lower
compatible
with
bone.
This
review
comprehensively
examines
current
β
evaluating
mechanical
properties,
particular
elasticity,
resistance.
this
end,
systematic
literature
search
was
carried
out,
where
81
articles
were
found
evaluate
outcomes.
In
addition,
also
covers
formation
alloy,
processing
methods
arc
melting,
physical,
mechanical,
electrochemical,
tribological,
biological
Because
β-Ti
have
closer
human
bone
compared
other
metal
they
help
reduce
stress
shielding.
is
important
because
alloy
allows
more
even
distribution
forces
by
having
similar
show
good
due
noble
oxide
layer,
facilitated
incorporation
stabilizers.
These
significant
improvements
strength
hardness.
Finally,
cytotoxicity
bacterial
adhesion,
depending
stabilizer
used.
there
persistent
require
detailed
critical
areas,
optimizing
composition
achieve
optimal
properties
different
clinical
applications.
it
crucial
study
long-term
effects
implants
body
advance
development
cutting-edge
manufacturing
techniques
guarantee
quality
biocompatibility
implants.
Coatings,
Год журнала:
2023,
Номер
13(12), С. 2064 - 2064
Опубликована: Дек. 9, 2023
Titanium
(Ti)
and
its
alloys
are
widely
recognized
as
preferred
materials
for
bone
implants
due
to
their
superior
mechanical
properties.
However,
natural
surface
bio-inertness
can
hinder
effective
tissue
integration.
To
address
this
challenge,
micro-arc
oxidation
(MAO)
has
emerged
an
innovative
electrochemical
modification
technique.
Its
benefits
range
from
operational
simplicity
cost-effectiveness
environmental
compatibility
scalability.
Furthermore,
the
distinctive
MAO
process
yields
a
porous
topography
that
bestows
versatile
functionalities
biological
applications,
encompassing
osteogenesis,
antibacterial,
anti-inflammatory
In
review,
we
undertake
examination
of
underlying
mechanism
governing
process,
scrutinize
multifaceted
influence
various
factors
on
coating
performance,
conduct
extensive
analysis
development
diverse
conferred
by
coatings,
discuss
practical
application
in
implants.
Finally,
provide
insights
into
limitations
potential
pathways
further
technology
field
implantation.
Clinical Implant Dentistry and Related Research,
Год журнала:
2023,
Номер
25(4), С. 767 - 781
Опубликована: Июнь 29, 2023
Abstract
Background
Antibiotics
are
the
most
effective
adjuncts
in
treatment
of
periodontitis.
However,
benefits
these
agents
treating
peri‐implantitis
still
debatable
and
demand
further
analysis.
Purpose
The
aim
this
review
was
to
critically
appraise
literature
on
use
antibiotics
treat
peri‐implantitis,
with
ultimate
goal
supporting
evidence‐based
clinical
recommendations,
defining
gaps
knowledge
guiding
future
studies
topic.
Methods
A
systematized
search
conducted
MEDLINE/PubMed
Cochrane
Library
databases
for
randomized
trials
(RCTs)
patients
treated
by
mechanical
debridement‐only
or
adjunctive
local
systemic
antibiotics.
Clinical
microbiological
data
were
extracted
from
RCTs
included.
findings
reviewed,
interpreted,
discussed.
An
overview
antibiotic‐loaded
dental
implant
materials
also
provided.
Results
Twelve
testing
local/systemic
Although
not
always
statistically
significant,
all
antibiotic‐treated
groups
had
greater
reductions
mean
PD
than
those
debridement‐only.
only
clinically
relevant
antibiotic
protocol
supported
one
RCT
low
risk
bias
long‐lasting
metronidazole
(MTZ).
Studies
using
ultrasonic
debridement
reported
better
outcomes.
No
date
have
tested
MTZ‐only
amoxicillin
(AMX)
as
open‐flap
debridement.
In
vitro/animal
suggested
that
biomaterials
antimicrobial
properties
promising
peri‐implantitis.
Conclusion
There
insufficient
support
a
particular
surgical
nonsurgical
therapy,
but
some
conclusions
may
be
drawn.
Systemic
MTZ
adjunct
is
an
improve
outcomes
treatment.
Future
should
assess
effects
+
AMX
optimal
decontamination
protocols
addition,
new
locally
delivered
drugs
surfaces
assessed
RCTs.
