International Journal of Biological Macromolecules,
Год журнала:
2023,
Номер
259, С. 128944 - 128944
Опубликована: Дек. 23, 2023
Self-assembly
involves
a
set
of
molecules
spontaneously
interacting
in
highly
coordinated
and
dynamic
manner
to
form
specific
supramolecular
structure
having
new
clearly
defined
properties.
Many
examples
this
occur
nature
many
more
came
from
research
laboratories,
with
their
number
increasing
every
day
via
ongoing
concerning
complex
biomolecules
the
possibility
harnessing
it
when
developing
applications.
As
phenomenon,
self-assembly
has
been
described
on
very
different
types
(biomolecules
including),
so
review
focuses
what
is
known
about
peptide
self-assembly,
its
origins,
forces
behind
it,
how
properties
resulting
material
can
be
tuned
relation
experimental
considerations,
some
biotechnological
applications
(in
which
main
protagonists
are
sequences
capable
self-assembly)
yet
regarding
development.
Journal of Biomaterials Applications,
Год журнала:
2024,
Номер
39(2), С. 96 - 116
Опубликована: Май 6, 2024
Objective:
Cartilage
injury
is
a
common
clinical
condition,
and
treatment
approaches
have
evolved
over
time
from
traditional
conservative
surgical
methods
to
regenerative
repair.
In
this
context,
hydrogels,
as
widely
used
biomaterials
in
the
field
of
cartilage
repair,
garnered
significant
attention.
Particularly,
responsive
hydrogels
(also
known
“smart
hydrogels”)
shown
immense
potential
due
their
ability
respond
various
physicochemical
properties
environmental
changes.
This
paper
aims
review
latest
research
developments
utilizing
more
systematic
comprehensive
meta-analysis
approach
evaluate
status
application
value
hydrogels.
The
goal
determine
whether
these
materials
demonstrate
favorable
therapeutic
effects
for
subsequent
applications,
thereby
offering
improved
patients
with
injuries.
Method:
study
employed
literature
search
method
summarize
progress
by
retrieving
on
subject
studies.
terms
included
“hydrogel”
“cartilage,”
covering
data
database
inception
up
October
2023.
quality
was
independently
evaluated
using
Review
Manager
v5.4
software.
Quantifiable
statistically
analyzed
R
language.
Results:
A
total
7
articles
were
retrieved
further
meta-analysis.
assessment,
studies
demonstrated
reliability
accuracy.
results
indicated
that
exhibit
unique
advantages
effective
outcomes
Subgroup
analysis
revealed
influences
factors
such
different
types
animal
models
effects.
Conclusion:
Responsive
show
substantial
provides
strong
scientific
evidence
applications
research,
hope
promoting
advancements
International Journal of Biological Macromolecules,
Год журнала:
2023,
Номер
259, С. 128944 - 128944
Опубликована: Дек. 23, 2023
Self-assembly
involves
a
set
of
molecules
spontaneously
interacting
in
highly
coordinated
and
dynamic
manner
to
form
specific
supramolecular
structure
having
new
clearly
defined
properties.
Many
examples
this
occur
nature
many
more
came
from
research
laboratories,
with
their
number
increasing
every
day
via
ongoing
concerning
complex
biomolecules
the
possibility
harnessing
it
when
developing
applications.
As
phenomenon,
self-assembly
has
been
described
on
very
different
types
(biomolecules
including),
so
review
focuses
what
is
known
about
peptide
self-assembly,
its
origins,
forces
behind
it,
how
properties
resulting
material
can
be
tuned
relation
experimental
considerations,
some
biotechnological
applications
(in
which
main
protagonists
are
sequences
capable
self-assembly)
yet
regarding
development.
