Frontiers in Nanotechnology,
Год журнала:
2025,
Номер
7
Опубликована: Апрель 14, 2025
Multimetallic
nanoparticles
(MMNPs)
produced
by
fungus-mediated
synthesis
have
attracted
a
lot
of
interest
as
an
environmentally
friendly
and
sustainable
nanotechnology
method.
Fungi
are
effective
bio-factories
that
create
complex
with
special
qualities
using
their
metabolic
enzymatic
capabilities.
When
compared
to
monometallic
counterparts,
MMNPs—which
composed
combinations
two
or
more
metals—offer
synergistic
benefits
such
increased
catalytic
activity,
higher
stability,
superior
biocompatibility.
In
addition
highlighting
the
structural
diversity
MMNPs,
core-shell,
alloy,
Janus
configurations,
this
review
investigates
mechanisms
underpinning
fungal-mediated
synthesis,
including
reduction
stabilisation
pathways.
Additionally
covered
characterisation
methods
for
examining
functionality,
morphology,
composition.
The
potential
applications
MMNPs
synthesized
fungi
in
biomedicine,
environmental
remediation,
biosensing,
catalysis
highlighted
article.
This
green
method,
which
makes
use
natural
fungus
multimetallic
systems,
responds
increasing
need
nanomaterials
opens
door
novel
uses
both
scientific
industrial
fields.
Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 7, 2025
Abstract
Metal‐protein
hybrid
materials
represent
a
novel
class
of
functional
that
exhibit
exceptional
physicochemical
properties
and
tunable
structures,
rendering
them
remarkable
applications
in
diverse
fields,
including
engineering,
biocatalysis,
biosensing,
biomedicine.
The
design
development
multifunctional
biocompatible
metal‐protein
have
been
the
subject
extensive
research
key
aspiration
for
practical
clinical
settings.
This
review
provides
comprehensive
analysis
strategies,
intrinsic
properties,
biomedical
these
materials,
with
specific
emphasis
on
their
potential
cancer
therapy,
drug
vaccine
delivery,
antibacterial
treatments,
tissue
regeneration.
Through
rational
design,
stable
can
be
synthesized
using
straightforward
methods,
enabling
therapeutic,
immunomodulatory,
other
desired
functionalities.
Finally,
outlines
existing
limitations
challenges
associated
evaluates
translation,
providing
insights
into
implementation
within
applications.
Biosensors,
Год журнала:
2025,
Номер
15(1), С. 38 - 38
Опубликована: Янв. 10, 2025
Integrating
functional
materials
with
photonic
and
optoelectronic
technologies
has
revolutionized
medical
diagnostics,
enhancing
imaging
sensing
capabilities.
This
review
provides
a
comprehensive
overview
of
recent
innovations
in
materials,
such
as
quantum
dots,
perovskites,
plasmonic
nanomaterials,
organic
semiconductors,
which
have
been
instrumental
the
development
diagnostic
devices
characterized
by
high
sensitivity,
specificity,
resolution.
Their
unique
optical
properties
enable
real-time
monitoring
biological
processes,
advancing
early
disease
detection
personalized
treatment.
However,
challenges
material
stability,
reproducibility,
scalability,
environmental
sustainability
remain
critical
barriers
to
their
clinical
translation.
Breakthroughs
green
synthesis,
continuous
flow
production,
advanced
surface
engineering
are
addressing
these
limitations,
paving
way
for
next-generation
tools.
article
highlights
transformative
potential
interdisciplinary
research
overcoming
emphasizes
importance
sustainable
scalable
strategies
harnessing
diagnostics.
The
ultimate
goal
is
inspire
further
innovation
field,
enabling
creation
practical,
cost-effective,
environmentally
friendly
solutions.
Langmuir,
Год журнала:
2024,
Номер
40(43), С. 22477 - 22503
Опубликована: Окт. 17, 2024
The
porous
materials
known
as
metal-organic
frameworks
(MOFs)
stand
out
for
their
enormous
surface
area,
adaptable
pore
size
and
shape,
structural
variety.
These
characteristics
make
them
well-suited
various
applications,
especially
in
healthcare.
This
review
thoroughly
summarizes
recent
studies
on
the
use
of
MOFs
drug
delivery,
biosensing,
therapeutics.
may
encapsulate
medications,
target
certain
cells
or
tissues,
regulate
release
over
time.
Additionally,
have
potential
to
be
used
biosensing
allowing
selective
detection
chemical
biological
substances.
MOFs'
optical
electrical
modified
biosensors
that
track
physiological
data.
show
targeted
delivery
regulated
therapeutic
substances
cancer
treatment.
In
addition,
they
work
potent
antibacterial
agents,
providing
a
less
dangerous
option
than
traditional
antibiotics
increase
antibiotic
resistance.
For
practical
further
research
is
required
well
more
consideration
problems
with
toxicity
biocompatibility.
addition
addressing
difficulties
promising
possibilities
this
study
intends
provide
insights
into
healthcare
Despite
several
essential
reviews
it
was
necessary
look
most
therapy
combined
concept.
Artificial Cells Nanomedicine and Biotechnology,
Год журнала:
2024,
Номер
52(1), С. 564 - 586
Опубликована: Дек. 5, 2024
Cancer
has
a
high
rate
of
incidence
and
mortality
throughout
the
world.
Although
several
conventional
approaches
have
been
developed
for
treatment
cancer,
such
as
surgery,
chemotherapy,
radiotherapy
thermal
therapy,
they
remarkable
disadvantages
which
result
in
inefficient
cancer.
For
example,
immunogenicity,
prolonged
treatment,
non-specificity,
metastasis
cost
are
considered
major
drawbacks
chemotherapy.
Therefore,
there
is
fundamental
requirement
development
breakthrough
technologies
cancer
suppression.
Polysaccharide-based
drug
delivery
systems
(DDSs)
most
reliable
carriers
therapy.
Polysaccharides,
kind
practical
biomaterials,
divided
into
types,
including
chitosan,
alginates,
dextran,
hyaluronic
acid,
cyclodextrin,
pectin,
etc.
Polysaccharides
extracted
from
different
natural
resources
(like
herbal,
marine,
microorganisms,
etc.).
The
potential
features
polysaccharides
made
them
candidates
therapeutics
to
sites;
simple
purification,
ease
modification
functionalization,
hydrophilicity,
serum
stability,
appropriate
loading
capacity,
biocompatibility,
bioavailability,
biodegradability
stimuli-responsive
sustained
release
manner
considerable
aspects
these
biopolymers.
This
review
highlights
applications
polysaccharides-based
DDSs
pharmaceutical
science
Cancers,
Год журнала:
2024,
Номер
16(24), С. 4234 - 4234
Опубликована: Дек. 19, 2024
Cancer
remains
a
predominant
global
health
concern,
necessitating
effective
treatment
options.
Conventional
cancer
therapies,
particularly
chemotherapy,
often
face
constraints
such
as
low
selectivity,
insufficient
solubility,
and
multidrug
resistance
(MDR),
which
diminish
effectiveness
exacerbate
negative
effects.
Metal
oxide
nanoparticles
(MONPs),
iron
oxide,
zinc
copper
offer
promising
solution
by
enhancing
targeted
drug
delivery,
reducing
systemic
toxicity,
mitigating
chemotherapy-induced
disabilities
like
neurotoxicity
cardiotoxicity.
Nanocarriers
conjugated
with
drugs
can
improve
delivery
within
the
body
enhance
their
circulation
in
bloodstream.
Recent
advancements
MONP
synthesis
functionalization
have
further
improved
stability
drug-loading
capacity,
making
them
valuable
tool
treatment.
MONPs
distinctive
physicochemical
characteristics,
enabling
better
imaging,
encapsulation,
medication
to
cancerous
cells.
These
nanocarriers
through
focused
controlled
release,
off-target
effects
addressing
resistance.
This
review
aims
explore
potential
of
efficient
for
anticancer
drugs,
limitations
traditional
chemotherapy
poor
specificity,
Additionally,
discusses
recent
functionalization,
stability,
compatibility.
Abstract
Organic
pollutants
like
malachite
green
pose
severe
environmental
risks
due
to
their
toxicity
and
persistence
in
water
bodies.
This
study
explores
an
eco‐friendly
solution
for
removal
via
photocatalytic
degradation
using
cobalt
nickel
oxide‐doped
zeolite
nanocomposites
(CoZ
NC
&
NiZ
NC),
synthesized
through
a
co‐precipitation
method.
X‐ray
diffraction
(XRD),
field
emission
scanning
electron
microscopy
(FESEM),
energy‐dispersive
(EDX)
analyses
confirm
the
formation
of
FCC‐structured
nanometal
oxides
on
matrix.
Optical
spectral
analysis
reveals
low
bandgap
energies
(2.84
eV
CoZ
2.81
enabling
efficient
photocatalysis
under
visible
light.
These
demonstrated
effective
photodegradation
green,
showcasing
remediation
potential.
Dielectric
studies
indicate
significantly
higher
dielectric
permittivity
compared
pristine
zeolite.
enhancement
is
attributed
internal
barrier
layer
capacitance
arising
from
variable
oxidation
states
metal
oxide
nanoparticles
interfacial
space
charge
polarization
between
matrix
dopants.
Uniformly
distributed
provide
superior
unevenly
arranged
NC.
Additionally,
lower
dissipation
factors
highlight
suitability
as
promising
k‐dielectric
materials
energy
storage
applications.
ABSTRACT
Metastasis
remains
a
leading
cause
of
cancer‐related
deaths,
defined
by
complex,
multi‐step
process
in
which
tumor
cells
spread
and
form
secondary
growths
distant
tissues.
Despite
substantial
progress
understanding
metastasis,
the
molecular
mechanisms
driving
this
development
effective
therapies
remain
incompletely
understood.
Elucidating
pathways
governing
metastasis
is
essential
for
discovery
innovative
therapeutic
targets.
The
rapid
advancements
sequencing
technologies
expansion
biological
databases
have
significantly
deepened
our
drivers
associated
drug
resistance.
This
review
focuses
on
particularly
roles
genetic
mutations,
epigenetic
changes,
post‐translational
modifications
progression.
We
also
examine
how
microenvironment
influences
metastatic
behavior
explore
emerging
strategies,
including
targeted
immunotherapies.
Finally,
we
discuss
future
research
directions,
stressing
importance
novel
treatment
approaches
personalized
strategies
to
overcome
improve
patient
outcomes.
By
integrating
contemporary
insights
into
basis
innovation,
provides
comprehensive
framework
guide
clinical
cancer.
Highlights in Science Engineering and Technology,
Год журнала:
2025,
Номер
125, С. 278 - 286
Опубликована: Фев. 18, 2025
Nanotechnology
has
been
developing
with
the
development
of
technology
and
made
great
progress
especially
in
field
biomedical
engineering
nanoparticles.
Biological
imaging
plays
an
important
role
medical
research.
Through
biological
technology,
researchers
can
intuitively
observe
structural
functional
changes
organisms
at
microscopic
level,
so
as
to
understand
mechanism
life
activities.
However,
current
traditional
radioactive
material
method,
problems
such
potential
safety
hazards
poor
effect,
which
limits
its
wide
application
clinical
scientific
To
address
these
challenges,
research
turned
nanotechnology
explore
advantages
bioimaging.
unique
physical
chemical
properties.
Nano-based
bioimaging
methods
not
only
improve
resolution
sensitivity
but
also
enhance
biocompatibility
reduce
organisms.
This
article
details
various
types
nanotechnology,
liposomes,
nanoparticles,
quantum
dots,
remarkable
results
achieved.
These
nano-imaging
technologies
realize
fine
cells,
tissues
even
whole
organism,
provide
strong
support
for
early
diagnosis
precision
treatment
diseases.
review
introduces
applications
effects
different
bioimaging,
explores
challenges
prospects
reveals
based
on
nanotechnology.