Fungal-mediated synthesis of multimetallic nanoparticles: mechanisms, unique properties, and potential applications DOI Creative Commons
Amanpreet K. Sidhu, Sanskruthi B. Agrawal, Naveen Kumar Verma

и другие.

Frontiers in Nanotechnology, Год журнала: 2025, Номер 7

Опубликована: Апрель 14, 2025

Multimetallic nanoparticles (MMNPs) produced by fungus-mediated synthesis have attracted a lot of interest as an environmentally friendly and sustainable nanotechnology method. Fungi are effective bio-factories that create complex with special qualities using their metabolic enzymatic capabilities. When compared to monometallic counterparts, MMNPs—which composed combinations two or more metals—offer synergistic benefits such increased catalytic activity, higher stability, superior biocompatibility. In addition highlighting the structural diversity MMNPs, core-shell, alloy, Janus configurations, this review investigates mechanisms underpinning fungal-mediated synthesis, including reduction stabilisation pathways. Additionally covered characterisation methods for examining functionality, morphology, composition. The potential applications MMNPs synthesized fungi in biomedicine, environmental remediation, biosensing, catalysis highlighted article. This green method, which makes use natural fungus multimetallic systems, responds increasing need nanomaterials opens door novel uses both scientific industrial fields.

Язык: Английский

Metal‐Protein Hybrid Materials: Unlocking New Frontiers in Biomedical Applications DOI Open Access
Yong Pan, Han Zhao, Wenyong Huang

и другие.

Advanced Healthcare Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 7, 2025

Abstract Metal‐protein hybrid materials represent a novel class of functional that exhibit exceptional physicochemical properties and tunable structures, rendering them remarkable applications in diverse fields, including engineering, biocatalysis, biosensing, biomedicine. The design development multifunctional biocompatible metal‐protein have been the subject extensive research key aspiration for practical clinical settings. This review provides comprehensive analysis strategies, intrinsic properties, biomedical these materials, with specific emphasis on their potential cancer therapy, drug vaccine delivery, antibacterial treatments, tissue regeneration. Through rational design, stable can be synthesized using straightforward methods, enabling therapeutic, immunomodulatory, other desired functionalities. Finally, outlines existing limitations challenges associated evaluates translation, providing insights into implementation within applications.

Язык: Английский

Процитировано

1

Integration of Functional Materials in Photonic and Optoelectronic Technologies for Advanced Medical Diagnostics DOI Creative Commons
Naveen Thanjavur,

Laxmi Bugude,

Young‐Joon Kim

и другие.

Biosensors, Год журнала: 2025, Номер 15(1), С. 38 - 38

Опубликована: Янв. 10, 2025

Integrating functional materials with photonic and optoelectronic technologies has revolutionized medical diagnostics, enhancing imaging sensing capabilities. This review provides a comprehensive overview of recent innovations in materials, such as quantum dots, perovskites, plasmonic nanomaterials, organic semiconductors, which have been instrumental the development diagnostic devices characterized by high sensitivity, specificity, resolution. Their unique optical properties enable real-time monitoring biological processes, advancing early disease detection personalized treatment. However, challenges material stability, reproducibility, scalability, environmental sustainability remain critical barriers to their clinical translation. Breakthroughs green synthesis, continuous flow production, advanced surface engineering are addressing these limitations, paving way for next-generation tools. article highlights transformative potential interdisciplinary research overcoming emphasizes importance sustainable scalable strategies harnessing diagnostics. The ultimate goal is inspire further innovation field, enabling creation practical, cost-effective, environmentally friendly solutions.

Язык: Английский

Процитировано

1

Applications of Metal–Organic Frameworks (MOFs) in Drug Delivery, Biosensing, and Therapy: A Comprehensive Review DOI

Bahar Saboorizadeh,

Rouholah Zare‐Dorabei, Maliheh Safavi

и другие.

Langmuir, Год журнала: 2024, Номер 40(43), С. 22477 - 22503

Опубликована: Окт. 17, 2024

The porous materials known as metal-organic frameworks (MOFs) stand out for their enormous surface area, adaptable pore size and shape, structural variety. These characteristics make them well-suited various applications, especially in healthcare. This review thoroughly summarizes recent studies on the use of MOFs drug delivery, biosensing, therapeutics. may encapsulate medications, target certain cells or tissues, regulate release over time. Additionally, have potential to be used biosensing allowing selective detection chemical biological substances. MOFs' optical electrical modified biosensors that track physiological data. show targeted delivery regulated therapeutic substances cancer treatment. In addition, they work potent antibacterial agents, providing a less dangerous option than traditional antibiotics increase antibiotic resistance. For practical further research is required well more consideration problems with toxicity biocompatibility. addition addressing difficulties promising possibilities this study intends provide insights into healthcare Despite several essential reviews it was necessary look most therapy combined concept.

Язык: Английский

Процитировано

7

Biosynthesis and biological activities of magnesium hydroxide nanoparticles using Tinospora cordifolia leaf extract DOI
Manickam Rajkumar,

S. I. Davis Presley,

Farid Menaa

и другие.

Bioprocess and Biosystems Engineering, Год журнала: 2024, Номер 47(12), С. 2111 - 2129

Опубликована: Сен. 16, 2024

Язык: Английский

Процитировано

6

Recent advances in polysaccharide-based drug delivery systems for cancer therapy: a comprehensive review DOI Creative Commons
Chou‐Yi Hsu, Omer Qutaiba B. Allela,

Ali M. Hussein

и другие.

Artificial Cells Nanomedicine and Biotechnology, Год журнала: 2024, Номер 52(1), С. 564 - 586

Опубликована: Дек. 5, 2024

Cancer has a high rate of incidence and mortality throughout the world. Although several conventional approaches have been developed for treatment cancer, such as surgery, chemotherapy, radiotherapy thermal therapy, they remarkable disadvantages which result in inefficient cancer. For example, immunogenicity, prolonged treatment, non-specificity, metastasis cost are considered major drawbacks chemotherapy. Therefore, there is fundamental requirement development breakthrough technologies cancer suppression. Polysaccharide-based drug delivery systems (DDSs) most reliable carriers therapy. Polysaccharides, kind practical biomaterials, divided into types, including chitosan, alginates, dextran, hyaluronic acid, cyclodextrin, pectin, etc. Polysaccharides extracted from different natural resources (like herbal, marine, microorganisms, etc.). The potential features polysaccharides made them candidates therapeutics to sites; simple purification, ease modification functionalization, hydrophilicity, serum stability, appropriate loading capacity, biocompatibility, bioavailability, biodegradability stimuli-responsive sustained release manner considerable aspects these biopolymers. This review highlights applications polysaccharides-based DDSs pharmaceutical science

Язык: Английский

Процитировано

5

Metal Oxide Nanoparticles as Efficient Nanocarriers for Targeted Cancer Therapy: Addressing Chemotherapy-Induced Disabilities DOI Open Access
Mohamed Taha Yassin, Fatimah Al-Otibi,

Sarah A. Al-Sahli

и другие.

Cancers, Год журнала: 2024, Номер 16(24), С. 4234 - 4234

Опубликована: Дек. 19, 2024

Cancer remains a predominant global health concern, necessitating effective treatment options. Conventional cancer therapies, particularly chemotherapy, often face constraints such as low selectivity, insufficient solubility, and multidrug resistance (MDR), which diminish effectiveness exacerbate negative effects. Metal oxide nanoparticles (MONPs), iron oxide, zinc copper offer promising solution by enhancing targeted drug delivery, reducing systemic toxicity, mitigating chemotherapy-induced disabilities like neurotoxicity cardiotoxicity. Nanocarriers conjugated with drugs can improve delivery within the body enhance their circulation in bloodstream. Recent advancements MONP synthesis functionalization have further improved stability drug-loading capacity, making them valuable tool treatment. MONPs distinctive physicochemical characteristics, enabling better imaging, encapsulation, medication to cancerous cells. These nanocarriers through focused controlled release, off-target effects addressing resistance. This review aims explore potential of efficient for anticancer drugs, limitations traditional chemotherapy poor specificity, Additionally, discusses recent functionalization, stability, compatibility.

Язык: Английский

Процитировано

5

Dielectric and Photocatalytic Performance of Heterostructured Nanocomposites of Cobalt and Nickel Oxides Embedded in Zeolite 4A Matrix. DOI Open Access

K. E. Rakesh,

Rosy Antony, S. Sandeep

и другие.

ChemistrySelect, Год журнала: 2025, Номер 10(2)

Опубликована: Янв. 1, 2025

Abstract Organic pollutants like malachite green pose severe environmental risks due to their toxicity and persistence in water bodies. This study explores an eco‐friendly solution for removal via photocatalytic degradation using cobalt nickel oxide‐doped zeolite nanocomposites (CoZ NC & NiZ NC), synthesized through a co‐precipitation method. X‐ray diffraction (XRD), field emission scanning electron microscopy (FESEM), energy‐dispersive (EDX) analyses confirm the formation of FCC‐structured nanometal oxides on matrix. Optical spectral analysis reveals low bandgap energies (2.84 eV CoZ 2.81 enabling efficient photocatalysis under visible light. These demonstrated effective photodegradation green, showcasing remediation potential. Dielectric studies indicate significantly higher dielectric permittivity compared pristine zeolite. enhancement is attributed internal barrier layer capacitance arising from variable oxidation states metal oxide nanoparticles interfacial space charge polarization between matrix dopants. Uniformly distributed provide superior unevenly arranged NC. Additionally, lower dissipation factors highlight suitability as promising k‐dielectric materials energy storage applications.

Язык: Английский

Процитировано

0

Tumor Metastasis: Mechanistic Insights and Therapeutic Intervention DOI Creative Commons

Lin Tang,

Peng Shen, Xiaoying Zhuang

и другие.

MedComm – Oncology, Год журнала: 2025, Номер 4(1)

Опубликована: Фев. 17, 2025

ABSTRACT Metastasis remains a leading cause of cancer‐related deaths, defined by complex, multi‐step process in which tumor cells spread and form secondary growths distant tissues. Despite substantial progress understanding metastasis, the molecular mechanisms driving this development effective therapies remain incompletely understood. Elucidating pathways governing metastasis is essential for discovery innovative therapeutic targets. The rapid advancements sequencing technologies expansion biological databases have significantly deepened our drivers associated drug resistance. This review focuses on particularly roles genetic mutations, epigenetic changes, post‐translational modifications progression. We also examine how microenvironment influences metastatic behavior explore emerging strategies, including targeted immunotherapies. Finally, we discuss future research directions, stressing importance novel treatment approaches personalized strategies to overcome improve patient outcomes. By integrating contemporary insights into basis innovation, provides comprehensive framework guide clinical cancer.

Язык: Английский

Процитировано

0

Advanced Progress of Nano-Based Delivery System for Bioimaging DOI Creative Commons
Zeyu Zhang

Highlights in Science Engineering and Technology, Год журнала: 2025, Номер 125, С. 278 - 286

Опубликована: Фев. 18, 2025

Nanotechnology has been developing with the development of technology and made great progress especially in field biomedical engineering nanoparticles. Biological imaging plays an important role medical research. Through biological technology, researchers can intuitively observe structural functional changes organisms at microscopic level, so as to understand mechanism life activities. However, current traditional radioactive material method, problems such potential safety hazards poor effect, which limits its wide application clinical scientific To address these challenges, research turned nanotechnology explore advantages bioimaging. unique physical chemical properties. Nano-based bioimaging methods not only improve resolution sensitivity but also enhance biocompatibility reduce organisms. This article details various types nanotechnology, liposomes, nanoparticles, quantum dots, remarkable results achieved. These nano-imaging technologies realize fine cells, tissues even whole organism, provide strong support for early diagnosis precision treatment diseases. review introduces applications effects different bioimaging, explores challenges prospects reveals based on nanotechnology.

Язык: Английский

Процитировано

0

X-ray Crystallographic Structural Profiling of Polyvinyl Alcohol (PVA) Caped Nickel Oxide Nanoparticle DOI Creative Commons
Mahfuzul Islam, Md. Tarikul Islam,

Md. Khalid Hossain Shishir

и другие.

Nano Trends, Год журнала: 2025, Номер unknown, С. 100106 - 100106

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0