Women s Health Reports, Год журнала: 2024, Номер 5(1), С. 945 - 953
Опубликована: Апрель 1, 2024
Язык: Английский
Applied Biosciences, Год журнала: 2024, Номер 3(3), С. 392 - 425
Опубликована: Сен. 22, 2024
The olive tree is currently cultivated worldwide, with higher incidence in Mediterranean Basin. Its climate highly favorable to the synthesis of phenolic compounds, stored leaves; their consumption has been linked a lower cancer and cardiovascular disorders for which research interest upon this feature increased last decade. This study aimed (i) review evidence about importance leaf extract (OLE) on human health physiological effect its major compounds; (ii) update state art studies conducted technological usage extract; (iii) report potential uses OLE pharmaceuticals, food production, cosmetics; (iv) prospect future clinical applications from diverse cultivars, especially metabolic inflammatory conditions such as polycystic ovary syndrome (PCOS). Overall, cultivars richer TPC, including TFC, αT, omega-3 omega-9, present main target supplementation alone or conjunction vitaminic due nutraceutical value disorders, chronic diseases, anti-aging treatments, whereas less water content might be useful substrates preservation. With regard prospects, it would great clarify specific mechanisms underlying beneficial effects neuro-immune design safer healthier nature-based medicine wide array costly prevalent metabolic-related syndromes, namely, PCOS.
Язык: Английский
Процитировано
4
The Journal of Obstetrics and Gynecology of India, Год журнала: 2025, Номер unknown
Опубликована: Янв. 22, 2025
Язык: Английский
Процитировано
0
International Journal of Women s Health, Год журнала: 2025, Номер Volume 17, С. 287 - 298
Опубликована: Фев. 1, 2025
Purpose: Polycystic Ovary Syndrome (PCOS) is a complex endocrine-metabolic disorder and associated with variety of health disorders. The management PCOS requires multidisciplinary care approach. COVID-19 pandemic affected access delivery care. aim this study was to assess the impact on experience those by PCOS. Patients Methods: An online survey conducted January 2021 July 2022 in Canada, open anyone who identified as having Data collected REDCap included questions demographics, symptoms, during pandemic. Results: majority (59%) respondents (n=194, mean age 34± 8 years) experienced pandemic-related employment changes self-reported high stress level (73± 21/100). Of reported body weight, 58% gained which they attributed unhealthy eating habits lack exercise pandemic, 16% lost credited increased physical activity shift towards healthier habits. ascribed COVID-related clinic cancellations, delayed appointments, long wait times for referrals lab work, facilities insufficient social support. Some voluntarily reduced services limit COVID exposure. COVID-19-related status perceived more important than their own PCOS-related symptoms. Virtual appointments via telehealth were regarded beneficial 20% users. Conclusion: Individuals an overall reduction supports. adapted use telemedicine, while others due inability manage further highlighted that often accessibility supports needed condition. Plain Language Summary: ovary syndrome affecting up 18% women can quality life across lifespan. It characterized irregular menstrual cycles, heavy bleeding, male-pattern hair growth, acne excess production male hormones. risk infertility, pregnancy complications, obesity, type 2 diabetes, cardiovascular diseases, mental disorders such anxiety, depression, negative self-image. Because its complexity, approach including endocrinologists, gynecologists, dietician, specialists, psychologists/psychiatrists. In paper, we describe findings self-administered explores patients' view challenges caused disruptions many patients struggled find support needed. unprecedented system but also presented opportunities alternative models. Our highlight need incorporate viable individualized options people chronic conditions PCOS, self-management prevent deterioration well-being unforeseen crises. While restricted proposed improvements provide distinct insights are international relevance there ample evidence similar experiences regarding around world. Keywords: polycystic syndrome, COVID-19, care, telehealth, supports, women's
Язык: Английский
Процитировано
0
Heart, Год журнала: 2025, Номер unknown, С. heartjnl - 324675
Опубликована: Фев. 24, 2025
Background Cardiovascular disease is the leading cause of death globally. Non-malignant gynaecological diseases (NMGD) significantly affect patient health and well-being may be associated with cardiovascular or cerebrovascular (C/CVD). Methods Seven databases were searched for relevant studies up to 21 April 2024. Observational reporting risk estimates 95% CIs association between NMGD C/CVD included. Data extracted by two independent reviewers. Random effects models used calculate summary relative (SRR) CI. Composite outcome was defined as a combination ischaemic heart disease, failure, peripheral vascular disease. The ROBINS-I tool study quality bias. Results We screened 6639 studies, which 59 eligible full-text review 28 included in our analysis, comprising total 3 271 242 individuals. majority (53.5%) scored having ‘serious’/‘critical’ Overall, individuals an had greater composite low heterogeneity among contributing (SRR 1.28, CI 1.20 1.37; n=16 I 2 =65.3%), 1.41, 1.31 1.51; n=21 =73.7%), 1.33, 1.18 =91.5%). In NMGD-specific analyses, its components those history endometriosis polycystic ovary syndrome. Conclusions found overall across all studies. However, from individual varied substantially.
Язык: Английский
Процитировано
0
Metabolism and Target Organ Damage, Год журнала: 2025, Номер 5(1)
Опубликована: Март 11, 2025
Polycystic ovary syndrome (PCOS) is a complex disorder with great heterogeneity of signs and symptoms. However, hyperandrogenism considered hallmark PCOS, presented by most affected women. Women PCOS are at high risk developing type 2 diabetes mellitus (T2DM), which associated insulin resistance (IR) hyperinsulinemia. In turn, hyperinsulinemia interferes the androgen production ovarian cells, worsens hyperandrogenism, initiating feedback cycle. also greater obesity. Indeed, dysfunctional adipose tissue in obesity contributes to T2DM affecting action secretion through multiple mechanisms, such as lipotoxicity, inflammation, adipokine signaling. Therefore, obesity-disrupted can be seen an important target for development women PCOS. Because positively non-pharmacological easily accessible strategies physical exercise, this review provides comprehensive summary benefits exercise improve health decrease
Язык: Английский
Процитировано
0
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Metabolites, Год журнала: 2025, Номер 15(4), С. 260 - 260
Опубликована: Апрель 10, 2025
Obesity increases the risk of anovulation, insulin resistance, hyperandrogenism, and endometrial dysfunction, resulting in women with infertility increasing preconceptional pregnancy complications. Bariatric surgery has been described as most effective intervention for obesity, improved fertility outcomes. However, its invasive nature potential nutritional deficiencies need a delayed conception post-surgery. On other hand, pharmacological treatments such glucagon-like-peptide 1 receptor agonists offer non-invasive alternatives promising results body weight, improving sensitivity restoring ovarian function. their use must be discontinued before due to fetal risks. Other available treatment options encompass topiramate, phentermine, Orlistat. The choice individualized considering cost-effectiveness, accessibility, obesity severity, reproductive goals, associated risks within each patient. A multidisciplinary approach is essential optimize metabolic health infertility. This review will examine impact on metabolism when comparing surgical interventions weight loss
Язык: Английский
Процитировано
0
Nursing and Midwifery Journal, Год журнала: 2025, Номер 22(11), С. 923 - 933
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0
Journal of Clinical Medicine, Год журнала: 2024, Номер 13(10), С. 2983 - 2983
Опубликована: Май 19, 2024
Women have an over 50% greater risk of dementia than men, which is a main topic much research. This review aims to investigate the impact woman’s reproductive history on risk. The consequences stillbirth are long-term health and psychosocial problems for women. Because awareness endangered pregnancy, many parents experience deep anxiety stress in subsequent pregnancies. There contradictory conclusions from research about abortion correlation. When it comes late age first birth, said be above 35 years old, was observed that older mothers decreased compared those who gave birth their 20s; however, being child mother connected with higher developing dementia. Using hormonal contraception can result as estrogen stimulates microglia-related Aβ removal reduces tau hyperphosphorylation. influence postmenopausal therapy duration period remains unclear. Although female disorders like endometriosis polycystic ovary syndrome reported increase dementia, this very limited, especially when endometriosis, needs further investigation. Interestingly, there no conclusion whether hypertensive pregnancy but most articles seem confirm theory.
Язык: Английский
Процитировано
3
Human Reproduction, Год журнала: 2024, Номер 39(8), С. 1823 - 1834
Опубликована: Июнь 11, 2024
What is the prospective risk of Type 2 diabetes (T2D) in Nordic women with polycystic ovary syndrome (PCOS) compared to controls?
Язык: Английский
Процитировано
2