Journal of Ophthalmic Inflammation and Infection,
Год журнала:
2024,
Номер
14(1)
Опубликована: Окт. 7, 2024
Abstract
Background
The
aim
of
this
study
was
to
characterize
bacterial
species,
aetiology
and
antibiotic
susceptibility
connected
keratitis
infections
in
Östergötland,
Sweden.
Methods
Retrospective
cross-sectional
based
on
electronic
health
records
for
the
period
2010–2019.
Records
patients
diagnosed
with
infectious
were
screened
microbiology
confirmed
keratitis.
Bacterial
species
their
antibiotics
determined
from
test
results.
Results
One-hundred
ninety
lab
culture-confirmed
included
analysis.
most
frequently
found
coagulase-negative
staphylococci
(39%),
Staphylococcus
aureus
(17%)
Cutibacterium
acnes
(10%).
Pseudomonas
spp.
Gram-negative
(7%).
Contact
lens
wear
severely
ill/blind
eye
top
two
aetiologies
associated
keratitis,
22%
also
glaucoma.
Most
isolates,
157
out
173,
susceptible
fluoroquinolones,
145
155
isolates
chloramphenicol.
Conclusion
Our
results
revealed
a
positive
rate
59%
samples
sent
laboratory.
There
high
recommended
antibiotics.
indicate
that
it
is
likely
are
receiving
correct
treatment.
Future
studies
necessary
monitor
changes
susceptibility.
Clinical Microbiology Reviews,
Год журнала:
2022,
Номер
35(2)
Опубликована: Янв. 19, 2022
The
spread
of
biofilms
on
medical
implants
represents
one
the
principal
triggers
persistent
and
chronic
infections
in
clinical
settings,
it
has
been
subject
many
studies
past
few
years,
with
most
them
focused
prosthetic
joint
infections.
We
review
here
recent
works
biofilm
formation
microbial
colonization
a
large
variety
indwelling
devices,
ranging
from
heart
valves
pacemakers
to
urological
breast
biliary
stents
endoscopic
tubes
contact
lenses
neurosurgical
implants.
focus
bacterial
abundance
distribution
across
different
devices
body
sites
role
environmental
features,
such
as
presence
fluid
flow
properties
implant
surface,
well
interplay
between
response
human
immune
system.
Contact Lens and Anterior Eye,
Год журнала:
2021,
Номер
45(5), С. 101539 - 101539
Опубликована: Ноя. 14, 2021
To
assess
systemic,
environmental
and
lifestyle
risk
factors
for
dry
eye
disease
(DED)
in
a
Mediterranean
Caucasian
population.A
cross-sectional
study
was
performed
on
120
participants
aged
between
18
89
years
(47.0
±
22.8
years).
Medical
history,
information
regarding
conditions
lifestyle,
Ocular
Surface
Disease
Index,
Dry
Eye
Questionnaire-5,
non-Invasive
(Oculus
Keratograph
5
M)
breakup
time,
tear
film
osmolarity
ocular
surface
staining
parameters
were
assessed
single
clinical
session
to
allow
DED
diagnosis
based
the
guidelines
of
Tear
Film
Society
Workshop
II
Diagnostic
Methodology
Report.
A
multivariate
logistic
regression
model
constructed
including
those
variables
with
p-value
less
than
0.15
univariate
analysis.A
prevalence
57.7
%
found.
No
age
differences
found
without
(U
=
1886.5,
p
0.243).
Nevertheless,
group
had
more
females
(X2
7.033,
0.008).
The
identified
as
potential
following:
female
sex,
sleep
hours
per
day,
menopause,
anxiety,
systemic
rheumatologic
disease,
use
anxiolytics,
daily
medication,
surgery,
poor
diet
quality,
ultra-processed
food
diet,
not
drinking
caffeine
exposure
air
conditioning
day.
Multivariate
revealed
that
menopause
anxiolytics
independently
associated
(p
≤
0.026
all).DED
is
factors.
These
findings
are
useful
identify
potentially
modifiable
factors,
addition
conventional
treatments
DED.
Eye & Contact Lens Science & Clinical Practice,
Год журнала:
2022,
Номер
48(3), С. 127 - 133
Опубликована: Фев. 22, 2022
Infectious
keratitis
is
a
rare
but
severe
condition
associated
with
range
of
ocular
and
systemic
predisposing
conditions,
including
trauma,
prior
surgery,
surface
disease,
contact
lens
(CL)
wear.
This
review
explores
the
epidemiology
infectious
keratitis,
specifically
differences
in
disease
incidence
risk
factors,
causative
organism
profile
virulence
characteristics
host
microbiome,
genetics,
gene
expression,
proteomics,
metabolomic
CL-related
non-CL-related
diseases.
Differences
exist
epidemiology,
demographics,
organisms,
their
diseases,
there
less
evidence
to
support
between
these
groups
individuals
pathways
disease.
Genetic
variations,
however,
immune
are
implicated
both
onset
severity
CL
non-CL
wearers.
As
technologies
metabolomics,
genomics
improved
be
better
able
process
small-volume
samples
from
surface,
will
understanding
interplay
CL,
profile,
microbial
environment.
may
result
more
personalized
approach
management
reduce
severity.
Discomfort
is
one
of
the
leading
causes
associated
with
contact
lens
dropout.
This
study
investigated
changes
in
tear
film
parameters
induced
by
wear
and
their
relationship
ocular
symptomology.
Thirty-four
wearers
(32.9
±
9.1
years,
7
men)
thirty-three
non-lens
(29.4
6.8
12
participated
this
clinical
setting.
Subjects
were
categorised
into
asymptomatic
(n
=
11),
moderate
15),
or
severe
symptomatic
8).
Clinical
evaluations
performed
morning,
including
blink
frequency
completeness,
pre-corneal
(NIBUT)
pre-lens
non-invasive
break-up
(PL-NIBUT),
lipid
interference
patterns,
meniscus
height.
Contact
had
a
higher
percentage
incomplete
blinks
(37%
vs.
19%,
p
<
0.001)
reduced
height
compared
to
controls
(0.24
0.08
0.28
0.10
mm,
0.014).
PL-NIBUT
was
shorter
than
NIBUT
(7.6
6.2
10.7
9.3
s.
0.002).
Significant
statistical
differences
between
groups
found
(p
0.01)
0.05),
recording
times
symptomatic.
Long-term
use
silicone–hydrogel
lenses
can
affect
stability,
production,
adequate
distribution
through
blinking.
Ocular
symptomology
correlates
stability
both
non-wearers.
