Biomedical Materials,
Год журнала:
2024,
Номер
19(5), С. 052007 - 052007
Опубликована: Авг. 21, 2024
Melanoma
is
a
common
malignant
tumor,
with
five-year
mortality
rate
as
high
62%
in
cases
of
metastatic
melanoma
according
to
cancer
statistics
(2024).
In
recent
years,
the
focus
research
has
predominantly
centered
on
immunotherapy
and
targeted
therapy,
grappling
challenges
such
resistance
immunogenicity.
The
discovery
nanoparticles
(NPs)
brought
nano-delivery
systems
forefront
diagnosis
treatment.
Although
certain
NPs,
like
liposomes,
have
gained
clinical
approval,
utilizing
most
for
treatment
remains
largely
exploratory.
inherent
limitations
NPs
present
major
obstacle
their
translation.
By
selecting
suitable
nanocarriers
functionalizing
optimize
systems,
combining
these
other
therapies,
it
possible
reduce
systemic
toxicity
associated
conventional
therapies
themselves.
This
optimization
could
significantly
improve
effectiveness
early
detection
timely
melanoma.
However,
there
been
few
reviews
combined
application
diagnostic
past
three
years.
review
summarizes
latest
applications
over
including
innovations
achievements
both
preclinical
studies,
offering
new
perspectives
potential
future
prospects.
It
integrates
data
patent
information,
highlights
trends
system
development,
offers
insights
into
Additionally,
discusses
opportunities
treatment,
providing
foundation
advancing
diagnosis,
Pharmaceutics,
Год журнала:
2024,
Номер
16(9), С. 1162 - 1162
Опубликована: Сен. 3, 2024
Despite
various
methods
currently
used
in
cancer
therapy,
breast
remains
the
leading
cause
of
morbidity
and
mortality
worldwide.
Current
therapeutics
face
limitations
such
as
multidrug
resistance,
drug
toxicity
off-target
effects,
poor
bioavailability
biocompatibility,
inefficient
delivery.
Nanotechnology
has
emerged
a
promising
approach
to
diagnosis,
imaging,
therapy.
Several
preclinical
studies
have
demonstrated
that
compounds
nanoparticles
formulated
from
platinum
group
metals
(PGMs)
effectively
treat
cancer.
PGMs
are
chemically
stable,
easy
functionalise,
versatile,
tunable.
They
can
target
hypoxic
microenvironments,
catalyse
production
reactive
oxygen
species,
offer
potential
for
combination
PGM
be
incorporated
with
anticancer
drugs
improve
efficacy
attached
targeting
moieties
enhance
tumour-targeting
efficiency.
This
review
focuses
on
therapeutic
outcomes
metal
(PGMNs)
against
cells
briefly
discusses
clinical
trials
these
treatment.
It
further
illustrates
applications
PGMNs
presents
opportunities
future
PGM-based
nanomaterial
combatting
Gels,
Год журнала:
2025,
Номер
11(4), С. 267 - 267
Опубликована: Апрель 4, 2025
The
growing
field
of
nanotechnology
has
recently
given
much
attention
to
nanogels,
which
are
versatile
formulas
and
have
promising
biomedical
applications.
Nanogels
or
nanohydrogels
undergone
significant
development
in
various
fields
industrial
research
meet
increasing
demands,
such
as
pharmaceuticals,
cosmetics,
food,
genetic
engineering.
that
contain
flavonoids,
secondary
metabolites
found
plants,
starting
become
distinctive
reveal
their
unique
characteristics.
objective
the
article
is
provide
a
comprehensive
overview
recent
articles
on
flavonoid-based
emphasizing
general
aspects
regarding
nanogel
formulation
structural
characterization,
well
advancements
made
field.
In
conclusion,
this
outlines
up-to-date
developments
synthesis,
formulation,
therapeutic
applications
important
role
nanotechnology.
Biomolecules,
Год журнала:
2025,
Номер
15(6), С. 802 - 802
Опубликована: Май 31, 2025
Cancer
is
a
highly
detrimental
and
fatal
illness
that
poses
significant
threat
to
human
well-being.
The
pattern
of
cancer
treatment
continuously
being
optimized
by
the
advancement
old
approaches
invention
novel
modes.
Nanotechnology-based
are
emerging
as
powerful
candidates
in
development
these
advanced
methods
for
treating
tumors.
This
article
provides
concise
overview
nanotechnology
or
nanomedicine
its
applications.
In
light
prevalent
issues,
such
inadequate
precision
targeting
initial
chemotherapy
drugs,
susceptibility
nucleic
acid
drugs
degradation,
gene
delivery,
occurrence
common
immune-related
adverse
events
during
immunotherapy,
we
explore
potential
integration
with
illustrative
examples
highlight
benefits
arise
from
utilization
nanomedicine.
