Frontiers in Pharmacology,
Год журнала:
2024,
Номер
15
Опубликована: Июнь 24, 2024
Infections
caused
by
multidrug-resistant
(MDR)
bacteria
have
become
a
major
challenge
for
global
healthcare
systems.
The
search
antibacterial
compounds
from
plants
has
received
increasing
attention
in
the
fight
against
MDR
bacteria.
As
medicinal
and
edible
plant,
Lophatherum
gracile
Brongn.
(
L.
)
favorable
effect.
However,
main
active
compound
its
antimicrobial
mechanism
are
not
clear.
Here,
our
study
first
identified
key
as
luteolin.
Meanwhile,
effect
of
luteolin
was
detected
using
broth
microdilution
method
time-kill
curve
analysis.
Luteolin
can
also
cause
morphological
structure
degeneration
content
leakage,
cell
wall/membrane
damage,
ATP
synthesis
reduction,
downregulation
mRNA
expression
levels
sulfonamide
quinolones
resistance
genes
Escherichia
coli
(MDR
E.
).
Furthermore,
untargeted
UPLC/Q-TOF-MS-based
metabolomics
analysis
bacterial
metabolites
revealed
that
significantly
changed
riboflavin
energy
metabolism,
chemotaxis
process
glycerophospholipid
metabolism
.
This
suggests
could
be
potential
new
food
additive
or
preservative
controlling
infection
spread.
Critical Reviews in Food Science and Nutrition,
Год журнала:
2023,
Номер
64(29), С. 10730 - 10748
Опубликована: Июль 5, 2023
With
the
growing
demand
for
functional
foods
having
better
nutraceutical
properties,
lactic
acid
bacteria
(LAB)
has
become
an
important
industrial
microorganism.
LAB
play
a
significant
role
in
food
industry
by
exhibiting
probiotic
properties
and
ability
to
produce
various
biologically
active
metabolites
such
as
γ-aminobutyric
(GABA),
exopolysaccharides
(EPSs),
conjugated
linoleic
(CLA),
bacteriocins,
reuterin
reutericyclin,
which
provides
enhanced
final
products.
are
also
known
several
specific
enzymes
essential
producing
substrate-derived
bioactive
compounds,
polyphenols,
peptides,
inulin-type
fructans
β-glucans,
fatty
acids,
polyols.
These
compounds
exhibit
many
health
benefits,
including
mineral
absorption,
oxidative
stress
protection,
blood
glucose
cholesterol-lowering
prevention
of
gastrointestinal
tract
infections
improved
cardiovascular
function.
Further,
metabolically
engineered
have
been
widely
used
nutritive
enhancement
different
products
application
CRISPR–Cas9
holds
tremendous
potential
engineering
cultures.
This
review
overview
use
probiotics,
its
fermented
products,
benefits
on
host.
Annual Review of Food Science and Technology,
Год журнала:
2023,
Номер
15(1), С. 211 - 239
Опубликована: Дек. 6, 2023
Interest
in
fermented
foods
is
increasing
because
are
promising
solutions
for
more
secure
food
systems
with
an
increased
proportion
of
minimally
processed
plant
and
a
smaller
environmental
footprint.
These
developments
also
pertain
to
novel
which
no
traditional
template
exists,
raising
the
question
how
develop
starter
cultures
such
fermentations.
This
review
establishes
framework
that
integrates
scientific
knowledge
selection
suitable
cultures.
Safety
considerations,
use
organisms
fermentations,
link
phylogeny
metabolic
properties
provide
criteria
culture
selection.
Such
approaches
can
select
microbial
strains
have
health
benefits.
A
science-based
approach
development
substantially
advance
their
value
through
systems,
products
health-promoting
microbes,
provision
improve
human
health.
Nanomaterials,
Год журнала:
2023,
Номер
13(15), С. 2152 - 2152
Опубликована: Июль 25, 2023
Addressing
the
critical
issue
of
water
pollution,
this
review
article
emphasizes
need
to
remove
hazardous
dyes
and
phenolic
compounds
from
wastewater.
These
pollutants
pose
severe
risks
due
their
toxic,
mutagenic,
carcinogenic
properties.
The
study
explores
various
techniques
for
remediation
organic
contaminants
wastewater,
including
an
enzymatic
approach.
A
significant
challenge
in
wastewater
treatment
is
loss
enzyme
activity
difficulty
recovery
post-treatment.
To
mitigate
these
issues,
examines
strategy
immobilizing
enzymes
on
newly
developed
nanostructured
materials
like
graphene,
carbon
nanotubes
(CNTs),
metal–organic
frameworks
(MOFs).
offer
high
surface
areas,
excellent
porosity,
ample
anchoring
sites
effective
immobilization.
evaluates
recent
research
immobilization
supports
applications
biocatalytic
nanoparticles.
It
also
analyzes
impact
operational
factors
(e.g.,
time,
pH,
temperature)
dye
compound
removal
using
enzymes.
Despite
promising
outcomes,
acknowledges
challenges
large-scale
implementation
offers
recommendations
future
tackle
obstacles.
This
concludes
by
suggesting
that
emerging
could
present
a
sustainable,
environmentally
friendly
solution
escalating
pollution
crisis.
Food Chemistry X,
Год журнала:
2024,
Номер
23, С. 101776 - 101776
Опубликована: Авг. 27, 2024
Fruits
contain
numerous
polyphenols
in
the
form
of
conjugates,
which
exhibit
low
antioxidant
activity.
Probiotic
fermentation
is
a
strategy
to
improve
activity
these
conjugated
by
modifying
their
structure.
However,
mechanisms
underlying
effects
functional
groups
and
derivatizations
on
antioxidative
activities
antioxidation
enhancement
probiotic
biotransformation
haven't
been
comprehensively
explored.
This
review
aimed
explore
structure-antioxidant
relationships
four
three
flavonoids
phenolic
acids.
Further,
elucidated
acids
as
glycoside,
methylated,
ester
conjugates
biotransformation.
Deglycosylation,
demethylation,
hydrolysis
catalyzed
enzymes
produced
