Molecules,
Год журнала:
2023,
Номер
29(1), С. 77 - 77
Опубликована: Дек. 22, 2023
Bell
peppers
(Capsicum
annuum
L.)
in
various
stages
of
maturity
are
widely
used
the
diets
individuals
and
food
industry;
they
consumed
both
fresh
after
thermal
processing.
However,
every
type
processing
impacts
overall
textural
bioactive
characteristics
this
plant-based
food.
In
order
to
quantify
changes
substances
color-structural
that
occur
during
selected
heat
treatments
(contact
grilling,
roasting,
roasting
combined
with
microwaving,
steam
cooking)
bell
at
three
(green,
yellow,
red),
analyses
antioxidant
activity,
reducing
sugar
content,
polyphenolic
compound
properties,
color
coordinates
L*a*b*
system
were
carried
out.
Some
processes
used,
such
as
contact
grilling
(15.43
mg
GAE/g
d.b.)
microwaving
(15.24
d.b.),
proved
be
beneficial
total
polyphenol
content
green
(2.75
increased.
The
(3.49
TE/g
steaming
(6.45
methods
decreased
activity
yellow
(14.29
d.b.).
Meanwhile,
(0.88
Glc/g
contact-grilling
(2.19
simultaneous
(0.66
(1.30
significantly
reduced
sugars
red
(4.41
studies
preserve
properties
peppers,
it
is
necessary
consider
use
appropriately
treatments,
depending
on
different
maturity.
proper
selection
adequate
treatment
can
not
only
increase
digestibility,
but
also
improve
bioavailability
from
raw
material.
Food Frontiers,
Год журнала:
2024,
Номер
5(3), С. 1126 - 1144
Опубликована: Фев. 8, 2024
Abstract
Ferulic
acid
(FA)
is
a
hydroxycinnamic
known
for
its
strong
antioxidant
activity
and
potential
benefits
intestinal
health.
However,
poor
water
solubility
instability
limit
effectiveness.
To
address
these
issues,
different
ways
have
been
explored
to
protect
FA
against
degradation
further
exert
benefits.
This
review
discusses
the
absorption
metabolism
of
in
gut,
as
well
impact
on
It
also
compares
delivery
systems,
such
nanoparticles,
electrospun
nanofibers,
microcapsules,
cross‐linked
polymer
gels,
Pickering
emulsions,
which
can
improve
solubility,
stability,
bioavailability
gastrointestinal
tract.
comprehensive
provides
valuable
insights
using
food,
pharmaceutical,
nutraceuticals
products.
Pharmaceuticals,
Год журнала:
2024,
Номер
17(6), С. 670 - 670
Опубликована: Май 22, 2024
Given
the
ongoing
rise
in
occurrence
of
allergic
disorders,
alterations
dietary
patterns
have
been
proposed
as
a
possible
factor
contributing
to
emergence
and
progression
these
conditions.
Currently,
there
is
significant
focus
on
development
therapies
that
utilize
natural
compounds
possessing
anti-allergy
properties.
Dietary
polyphenols
plant
metabolites
intensively
researched
due
their
well-documented
anti-inflammatory,
antioxidant,
immunomodulatory
characteristics,
making
them
one
most
prominent
bioactive
chemicals.
This
study
seeks
discuss
in-depth
mechanisms
by
which
molecules
may
exert
anti-allergic
effects,
namely
through
capacity
diminish
allergenicity
proteins,
modulate
immune
responses,
modify
composition
gut
microbiota.
However,
further
investigation
required
fully
understand
effects.
paper
examines
existing
evidence
from
experimental
clinical
studies
supports
idea
different
polyphenols,
such
catechins,
resveratrol,
curcumin,
quercetin,
others,
can
reduce
inflammation,
relieve
symptoms
food
allergy,
asthma,
atopic
dermatitis,
rhinitis,
prevent
response.
In
summary,
possess
properties
be
utilized
for
developing
both
preventative
therapeutic
strategies
targeting
The
also
discusses
constraints
investigating
broad
usage
well
potential
avenues
future
research.
Antioxidants and Redox Signaling,
Год журнала:
2024,
Номер
40(7-9), С. 564 - 593
Опубликована: Янв. 22, 2024
Significance:
Currently,
a
large
amount
of
evidence
beneficial
effects
diets
enriched
with
polyphenols
on
various
aspects
health
has
been
accumulated.
These
phytochemicals
have
geroprotective
potential
slowing
down
the
pathological
processes
associated
aging
and
ensuring
longevity.
In
this
study,
comprehensive
analysis
was
conducted
to
determine
adherence
individual
geroprotector
criteria.
Data
from
experimental
models,
clinical
trials,
epidemiological
studies
were
analyzed.
Recent
Advances:
Sixty-two
described
increase
life
span
improve
biomarkers
in
animal
models.
They
act
via
evolutionarily
conserved
molecular
mechanisms,
including
hormesis
maintenance
redox
homeostasis,
epigenetic
regulation,
response
cellular
damage,
metabolic
control,
anti-inflammatory
senolytic
activity.
Epidemiological
suggest
that
certain
for
prevention
treatment
diseases,
cancer,
disorders,
cardiovascular
conditions
humans.
Critical
Issues:
Among
reviewed
phytochemicals,
chlorogenic
acid,
quercetin,
epicatechin,
genistein,
resveratrol,
curcumin
identified
as
compounds
highest
potential.
However,
there
is
lack
unambiguous
information
effectiveness
safety
increasing
span,
preventing
treating
aging-associated
diseases
Future
Directions:
Further
research
needed
fully
understand
considering
their
long-term
consumption,
modification
bioavailability,
complex
interactions
between
different
groups
other
well
individuals
status.
Antioxid.
Redox
Signal.
40,
564–593.
Color
images
are
available
online.
Nutrients,
Год журнала:
2024,
Номер
16(13), С. 2041 - 2041
Опубликована: Июнь 27, 2024
With
the
recognition
of
importance
gut-brain
axis
in
Parkinson's
disease
(PD)
etiology,
there
is
increased
interest
developing
therapeutic
strategies
that
target
α-synuclein,
hallmark
abhorrent
protein
PD
pathogenesis,
which
may
originate
gut.
Research
has
demonstrated
inhibiting
aggregation,
oligomerization,
and
fibrillation
α-synuclein
are
key
for
modification.
Polyphenols,
rich
fruits
vegetables,
drawing
attention
their
potential
role
this
context.
In
paper,
we
reviewed
how
polyphenols
influence
composition
functional
capabilities
gut
microbiota
resulting
microbial
metabolites
potentially
enhance
modulation
aggregation.
Understanding
interaction
between
identifying
specific
microbes
efficacy
crucial
precision
nutrition
based
on
microbiome.
Nutrients,
Год журнала:
2024,
Номер
16(7), С. 1047 - 1047
Опубликована: Апрель 3, 2024
Inflammation
is
an
important
biological
response
to
any
tissue
injury.
The
immune
system
responds
stimulus,
such
as
irritation,
damage,
or
infection,
by
releasing
pro-inflammatory
cytokines.
overproduction
of
cytokines
can
lead
several
diseases,
e.g.,
cardiovascular
joint
disorders,
cancer,
and
allergies.
Emerging
science
suggests
that
whole
grains
may
lower
the
markers
inflammation.
Whole
are
a
significant
source
dietary
fiber
phenolic
acids,
which
have
inverse
association
with
risk
Both
cereals
pseudo-cereals
rich
in
fiber,
arabinoxylan
β-glucan,
hydroxycinnamic
acids
hydroxybenzoic
predominantly
present
bran
layer.
However,
mechanisms
underlying
widely
reported
between
grain
consumption
disease
not
fully
understood.
modulatory
effects
on
inflammation
likely
be
influenced
including
effect
acids.
While
some
these
direct,
others
involve
gut
microbiota,
transforms
bioactive
substances
into
more
beneficial
metabolites
modulate
inflammatory
signaling
pathways.
Therefore,
purpose
this
review
twofold:
first,
it
discusses
highlights
their
potential;
second,
examines
health
benefits
components
impacts
subclinical
markers,
role
microbiota.
Overall,
while
there
promising
evidence
for
anti-inflammatory
properties
grains,
further
research
needed
understand
fully.
Pharmacological Research,
Год журнала:
2024,
Номер
207, С. 107324 - 107324
Опубликована: Июль 24, 2024
This
review
rigorously
assesses
the
burgeoning
research
into
role
of
polyphenols
in
modulating
mitophagy,
an
essential
cellular
mechanism
for
targeted
removal
impaired
mitochondria.
These
natural
compounds,
known
their
low
toxicity,
are
underscored
potential
therapeutic
strategies
against
a
diverse
array
diseases,
such
as
neurodegenerative,
cardiovascular,
and
musculoskeletal
disorders.
The
analysis
penetrates
deeply
molecular
mechanisms
whereby
promote
particularly
by
influencing
crucial
signaling
pathways
transcriptional
regulators,
including
phosphatase
tensin
homolog
(PTEN)
induced
putative
kinase
1
(PINK1)/parkin
forkhead
box
O3
(FOXO3a)
pathways.
Noteworthy
discoveries
include
neuroprotective
properties
resveratrol
curcumin,
which
affect
both
autophagic
mitochondrial
dynamics,
pioneering
integration
with
other
substances
to
amplify
effectiveness.
Furthermore,
confronts
issue
polyphenol
bioavailability
emphasizes
imperative
clinical
trials
corroborate
viability.
By
delivering
exhaustive
synthesis
contemporary
insights
recent
advancements
mitophagy
research,
this
endeavors
catalyze
additional
foster
creation
innovative
modalities
that
exploit
distinctive
attributes
manage
prevent
disease.
