Maximally efficient prediction in the early fly visual system may support evasive flight maneuvers DOI Creative Commons
Siwei Wang, Idan Segev, Alexander Borst

и другие.

PLoS Computational Biology, Год журнала: 2021, Номер 17(5), С. e1008965 - e1008965

Опубликована: Май 20, 2021

The visual system must make predictions to compensate for inherent delays in its processing. Yet little is known, mechanistically, about how prediction aids natural behaviors. Here, we show that despite a 20-30ms intrinsic processing delay, the vertical motion sensitive (VS) network of blowfly achieves maximally efficient prediction. This enables fly fine-tune complex, yet brief, evasive flight maneuvers according initial ego-rotation at time detection threat. Combining rich database behavioral recordings with detailed compartmental modeling VS network, further has axonal gap junctions are critical optimal During maneuvers, subpopulation directly innervates neck motor center can convey predictive information fly’s future ego-rotation, potentially crucial ongoing control. These results suggest novel sensory-motor pathway links sensory behavior.

Язык: Английский

A visuomotor circuit for evasive flight turns in Drosophila DOI Creative Commons
Hyosun Kim,

Hayun Park,

Joowon Lee

и другие.

Current Biology, Год журнала: 2023, Номер 33(2), С. 321 - 335.e6

Опубликована: Янв. 1, 2023

Язык: Английский

Процитировано

18
Neuromuscular basis of Drosophila larval rolling escape behavior DOI Creative Commons
Patricia C. Cooney, Yuhan Huang, Wenze Li

и другие.

Proceedings of the National Academy of Sciences, Год журнала: 2023, Номер 120(51)

Опубликована: Дек. 14, 2023

When threatened by dangerous or harmful stimuli, animals engage in diverse forms of rapid escape behaviors. In Drosophila larvae, one type response involves C-shaped bending and lateral rolling followed forward crawling. The sensory circuitry that promotes larval has been extensively characterized; however, the motor programs underlying are unknown. Here, we characterize neuromuscular basis behavior. We used high-speed, volumetric, Swept Confocally Aligned Planar Excitation (SCAPE) microscopy to image muscle activity during rolling. Unlike sequential peristaltic contractions progress from segment backward crawling, progresses circumferentially propose progression muscular contraction around larva's circumference results a transient misalignment between weight ground support forces, which generates torque induces stabilizing body rotation. Therefore, successive cycles slight reactive aligning rotation lead continuous motion. Supporting our biomechanical model, found disrupting groups undergoing circumferential leads defects. use EM connectome data identify premotor connectivity patterns could drive behavior perform neural silencing approaches demonstrate crucial role group glutamatergic neurons Our reveal body-wide putative circuit organization for execution response.

Язык: Английский

Процитировано

17
Non-canonical Receptive Field Properties and Neuromodulation of Feature-Detecting Neurons in Flies DOI Creative Commons
Carola Städele, Mehmet F. Keleş, Jean-Michel Mongeau

и другие.

Current Biology, Год журнала: 2020, Номер 30(13), С. 2508 - 2519.e6

Опубликована: Май 21, 2020

Several fundamental aspects of motion vision circuitry are prevalent across flies and mice. Both taxa segregate ON OFF signals. For any given spatial pattern, detectors in both tuned to speed, selective for one four cardinal directions, modulated by catecholamine neurotransmitters. These similarities represent conserved, canonical properties the functional circuits computational algorithms vision. Less is known about feature detectors, including how receptive field differ from pathway or whether they under neuromodulatory control impart plasticity detection salient objects a moving background. Here, we investigated 19 types putative lobula columnar (LC) neurons optic lobe fruit fly Drosophila melanogaster characterize divergent selection. We identified LC12 LC15 as detectors. encodes bars, whereas discrete objects, mostly independent size. Neither contrast polarity, direction, highlighting key differences underlying show that onset background suppresses object responses LC15. Surprisingly, application octopamine, which released during flight, reverses suppressive influence motion, rendering LCs able track superimposed against motion. Our results provide comparative framework function modulation new insights into neuronal mechanisms involved visual detection.

Язык: Английский

Процитировано

49
Object-Displacement-Sensitive Visual Neurons Drive Freezing in Drosophila DOI Creative Commons
Ryosuke Tanaka, Damon A. Clark

Current Biology, Год журнала: 2020, Номер 30(13), С. 2532 - 2550.e8

Опубликована: Май 21, 2020

Язык: Английский

Процитировано

39
Maximally efficient prediction in the early fly visual system may support evasive flight maneuvers DOI Creative Commons
Siwei Wang, Idan Segev, Alexander Borst

и другие.

PLoS Computational Biology, Год журнала: 2021, Номер 17(5), С. e1008965 - e1008965

Опубликована: Май 20, 2021

The visual system must make predictions to compensate for inherent delays in its processing. Yet little is known, mechanistically, about how prediction aids natural behaviors. Here, we show that despite a 20-30ms intrinsic processing delay, the vertical motion sensitive (VS) network of blowfly achieves maximally efficient prediction. This enables fly fine-tune complex, yet brief, evasive flight maneuvers according initial ego-rotation at time detection threat. Combining rich database behavioral recordings with detailed compartmental modeling VS network, further has axonal gap junctions are critical optimal During maneuvers, subpopulation directly innervates neck motor center can convey predictive information fly’s future ego-rotation, potentially crucial ongoing control. These results suggest novel sensory-motor pathway links sensory behavior.

Язык: Английский

Процитировано

34