Microorganisms, Год журнала: 2024, Номер 12(10), С. 2106 - 2106
Опубликована: Окт. 21, 2024
Toxoplasmosis is a disease caused by the intracellular protozoan
Язык: Английский
Parasite Immunology, Год журнала: 2024, Номер 46(7)
Опубликована: Июль 1, 2024
ABSTRACT Toxoplasmosis as a zoonotic disease has worldwide distribution and can infect wide range of animal hosts, well at least one third the world's human population. The is usually mild or asymptomatic in immunocompetent individuals, but dormant tissue cysts survive especially brain for host lifespan, known latent toxoplasmosis (LT). Recent studies suggest that LT have certain neurological, immunological psychological behavioural effects on including schizophrenia, bipolar disorder, Alzheimer's disease, depression, suicide anxiety sleeping disorders. are controversial, their exact mechanisms action not yet fully understood. This review aims to provide an overview potential effects, basic alteration neurotransmitter levels, immune activation central nervous system induction oxidative stress. Additionally, beneficial LT, explanation within framework manipulation hypothesis, finally, challenges limitations current research discussed.
Язык: Английский
Процитировано
2
Research Square (Research Square), Год журнала: 2024, Номер unknown
Опубликована: Март 6, 2024
Abstract Background Toxoplasmosis is a chronic protozoan parasitic infection that affects nearly one-third of the global population. During COVID-19 pandemic, cases were observed in patients with and toxoplasmosis. Therefore, this systematic review meta-analysis aimed to determine frequency Toxoplasma gondii exposure COVID-19. Methods A literature search was conducted six databases (PubMed, Scopus, Embase, Web Science, ScienceDirect, Google Scholar) until March 3, 2024. Study selection, quality assessment, data extraction performed independently by three investigators. Statistical analysis using R version 4.3, applying random-effects model. The included observational studies assessed "JBI-MAStARI". Results total 5,936 retrieved, 13 which final meta-analysis. sample 2,947 from four countries, whom approximately 43.26% men 49.41% women. Among patients, 1,323 showed evidence T. through IgG detection, while 1,302 specifically examined for presence IgM 36 positive identified. , determined COVID-19, reached 49% (95% CI: 34-63%; participants; studies; I 2 = 98%, p < 0.01). In addition, evaluated 2% 0-6%; 6 94%, Conclusion It shown almost half had previous IgG, small percentage, 2%, active detection.
Язык: Английский
Процитировано
0
BMC Public Health, Год журнала: 2024, Номер 24(1)
Опубликована: Окт. 19, 2024
Toxoplasmosis is a chronic protozoan parasitic infection that affects nearly one-third of the global population. During COVID-19 pandemic, cases were observed in patients with and toxoplasmosis. Therefore, this systematic review meta-analysis aimed to determine frequency Toxoplasma gondii exposure COVID-19. A literature search was conducted six databases or tools (PubMed, Scopus, Embase, Web Science, ScienceDirect, Google Scholar) until March 3, 2024. Study selection, quality assessment, data extraction performed independently by three investigators. Statistical analysis using R version 4.3, applying random-effects model. The included observational studies assessed "JBI-MAStARI". total 5,936 retrieved, 13 which final meta-analysis. sample 2,947 from four countries, whom approximately 43.3% men 49.4% women. Among patients, 1,323 showed evidence T. through IgG detection, while 1,302 explicitly examined for IgM 36 positive identified. gondii, determined presence COVID-19, reached 49% (95% CI: 34–63%; participants; studies; I2 = 98%, p < 0.01). In addition, evaluated 2% 0–6%; 6 94%, It shown almost half had previous IgG, small percentage, 2%, active detection. Although results indicate possible correlation between it essential note study based on research, precludes establishing causal relationship. Consequently, further research required deepen understanding interaction two conditions. Joanna Briggs Institute Meta-Analysis Statistics Assessment Review Instrument (JBI-MAStARI), Prospective International Registry Systematic Reviews (PROSPERO), Preferred Reporting Items Meta-Analyses (PRISMA).
Язык: Английский
Процитировано
0
Microorganisms, Год журнала: 2024, Номер 12(10), С. 2106 - 2106
Опубликована: Окт. 21, 2024
Toxoplasmosis is a disease caused by the intracellular protozoan
Язык: Английский
Процитировано
0