COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis

JMIR Public Health and Surveillance, Год журнала: 2024, Номер 10, С. e54769 - e54769

Опубликована: Апрель 30, 2024

The unprecedented emergence of the COVID-19 pandemic necessitated development and global distribution vaccines, making understanding vaccine acceptance hesitancy crucial to overcoming barriers vaccination achieving widespread immunization.

Язык: Английский

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COVID-19 Vaccination Acceptance Among the Diabetic Population in the Northwestern Region of Romania: Insights From an Autofill Survey

Cureus, Год журнала: 2025, Номер unknown

Опубликована: Март 30, 2025

Introduction The global experience of COVID-19 has highlighted the underestimated importance vaccination as a preventive measure. Vaccine acceptance can be influenced by multiple factors, which significantly reduced through improved promotion strategies. This study aims to identify these factors and explore potential strategies enhance vaccine uptake among diabetic population. Materials methods A cross-sectional was conducted on 189 patients diagnosed with type 1 or 2 diabetes. selected were from northwestern region Romania, largest most significant area for diabetes treatment. We used an adapted, pretested, self-administered questionnaire developed authors in collaboration other medical professionals. Participants completed 27-item survey covering personal sociodemographics, history related diabetes, comorbidities COVID-19, level education, religion, ethnicity, administered, attitude toward vaccination, including hesitancy. Descriptive inferential statistics performed, results presented percentages associations. difference between groups that accepted refused examined using Chi-square test, p-value < 0.05 considered statistically significant. If significant, odds ratio (OR) calculated 95% confidence interval. Results participants 96 (50.8%) females 93 (49.2%) males. Most patients, 116 (61.4%), 51 70 years old. Moreover, 56 (29.6%) had only high school terms education level. From history, 186 (98.4%) 162 (85.7%) taking oral antidiabetics, 94 (49.7%) cardiovascular diseases, 161 (85.2%) at least one infection. One hundred seventy-three vaccinated against COVID-19. common vaccine, 143 (82.7%), Pfizer. principal determinant acceptance, identified 109 (63%) participants, individual health well-being others. For those who did not choose get vaccinated, fear side effects (7; 43.8%) main reason. Regarding administration third dose, reason hesitancy is overcome perception (22; 20.6%), while remains same, i.e., others (56; 84.8%). relationship variables like marital status, age, orthodox occupation, education. Conclusions Variables such age positively influence uptake. Comprehensive medicine, starting early integrated within healthcare system, essential fostering understanding vaccination.

Язык: Английский

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COVID-19 Vaccine Effectiveness and Risk Factors of Booster Failure in 480,000 Patients with Diabetes Mellitus: A Population-Based Cohort Study

Microorganisms, Год журнала: 2025, Номер 13(5), С. 979 - 979

Опубликована: Апрель 24, 2025

To investigate the real-world effectiveness of COVID-19 vaccines in a large cohort patients with diabetes mellitus (DM), we analyzed all >18-year-old registered Brazilian nationwide surveillance database between February 2020 and 2023. The primary outcome interest was vaccine against death, evaluated using multivariate logistic regression models. Among 2,131,089 SIVEP-Gripe, 482,677 (22.6%) had DM. After adjusting for covariates, DM higher risk death than those without comorbidities (adjusted odds ratio [aOR] = 1.43, 95% CI, 1.39-1.47). For (72.7%, 70.5-74.7) (73.4%, 68.2-76.7), similar after booster dose. However, it reduced associated other (60.5%; 57.5-63.2). strongest factor failure omicron variant (aOR 27.8, 19.9-40.1). Our study revealed that provided robust protection individuals our findings underscore need to update develop tailored strategies diabetes, especially additional underlying conditions.

Язык: Английский

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Anti-SARS-CoV-2 antibody levels predict outcome in COVID-19 patients with type 2 diabetes: a prospective cohort study

Scientific Reports, Год журнала: 2023, Номер 13(1)

Опубликована: Окт. 26, 2023

Patients with type 2 diabetes (T2D) constitute one of the most vulnerable subgroups in COVID-19. Despite high vaccination rates, a correlate protection to advise strategies for novel SARS-CoV-2 variants concern and lower mortality this high-risk group is still missing. It further unclear what antibody levels provide whether pre-existing organ damage affects threshold. To address these gaps, we conducted prospective multicenter cohort study on 1152 patients COVID-19 from five hospitals. were classified by status. Anti-SARS-CoV-2-spike-antibodies, creatinine NTproBNP measured hospital admission. Pre-specified endpoints all-cause in-hospital-mortality, ICU admission, endotracheal intubation, oxygen administration. Propensity score matching was applied increase comparability. We observed significantly anti-SARS-CoV-2-spike-antibodies diabetic non-survivors compared survivors (mean, 95% CI 351BAU/ml, 106-595 vs. 1123, 968-1279, p < 0.001). Mortality risk increased two-fold each standard deviation-decrease (aHR 1.988, 1.229-3.215, = 0.005). T2D requiring administration, intubation admission had than those who did not (p 0.001, 0.046, 0.011). While worse outcomes non-diabetic patients, differences less pronounced propensity-score-matched patients. Anti-SARS-CoV-2 spike antibodies are inversely associated intensive care in-hospital Pre-existing comorbidities may have greater impact outcome status alone.

Язык: Английский

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A Critical Review on the Long-term COVID-19 Impacts on Patients with Diabetes

The American Journal of Medicine, Год журнала: 2024, Номер unknown

Опубликована: Март 1, 2024

Язык: Английский

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Covid-19 vaccine hesitancy and its predictors among diabetic patients on follow-up at public hospitals in Nekemte Town, Western Ethiopia

PLoS ONE, Год журнала: 2024, Номер 19(7), С. e0305200 - e0305200

Опубликована: Июль 8, 2024

Background Understanding and addressing the concerns of vaccine-hesitant individuals, including those with chronic diseases, is key to increasing vaccine acceptance uptake. However, in Ethiopia, there limited evidence on COVID-19 hesitancy predictor variables among diabetic patients. Hence, study aimed assess Covid-19 Vaccine Hesitancy Predictor Diabetic Patients Follow-Up at Public Hospitals Nekemte Town, Western Ethiopia. Method Facility based cross sectional was conducted 422 patients attending public hospitals Ethiopia between January, February, 2023. Study participants were recruited by systematic random sampling. The data collected interviewee administered pre-tested structured survey questioner. entered cleaned using Epi-Data software 4.6 version. analyzed SPSS. 25.0 Statical software. Descriptive statistics like frequency, mean percentage, binary logistic regression applied identify independent predictors association declared p-value 0.05. Result overall magnitude 15.2% (95% CI: 11.6–18.7). top three listed reasons for were: negative information about (32.90%), lack enough (21.80%), safety concern (19.40%). vaccination uptake diabetes independently influenced age 40–49 (Adjusted Odd Ratio [AOR] = 4.52(1.04–19.66)), having awareness (AOR 0.029(0.001–0.86)), a great deal trust development 0.028(0.002–0.52)), fear amount 0.05(0.003–0.79)) preparation, vaccinated 0.13(0.04–0.51)), perceived exposure infection after as strongly agree/agree 0.03(0.01–0.17))and neither agree nor disagree 0.07(0.02–0.30)). Conclusion relatively low. identified age, awareness, history, preparation status infection. relevant agency should focus efforts translating these high levels into actual uptake, through targeting identifying availability high-risk patient.

Язык: Английский

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Examining the longitudinal effect of depressive symptoms on physical activity in persons with type 2 diabetes during the COVID-19 pandemic.

Mental health and physical activity, Год журнала: 2024, Номер 27, С. 100647 - 100647

Опубликована: Окт. 1, 2024

Язык: Английский

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What factors affect acceptance attitudes towards vaccination amidst a major public health crisis? A national cross-sectional study

BMJ Open, Год журнала: 2024, Номер 14(12), С. e088245 - e088245

Опубликована: Дек. 1, 2024

Vaccine hesitancy persists as a significant global health concern, especially during public crises. This study aimed to explore factors influencing vaccination acceptance major crisis and establish model of factors.

Язык: Английский

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Stress and quality of life among susceptible Thai people during COVID-19 pandemic

International Journal of Public Health Science (IJPHS), Год журнала: 2023, Номер 12(4), С. 1687 - 1687

Опубликована: Окт. 4, 2023

People with underlying disease (diabetes mellitus, and hypertension) could be stressed during COVID-19 pandemic. This study was investigated stress levels quality of life among diabetes mellitus and/or hypertension patients, factors related to in Khon Kaen cross-sectional analytical conducted 270 samples. Multilevel logistic regression performed identify the influence level (QoL). The results showed that most samples had a moderate (78.5%), high (3.3%). For overall QoL, it found them (77.8%), poor (7.8%). likelihood QOL 5.5 times (adj. OR=5.5; 95% CI: 1.6 18.1) income decreasing due economic downturn, no impact not immunized 3.4 OR=3.4; CI:1.2 9.2) statistical significance at 0.05 level. It concluded nearly 2.5–3 times, life, issues affected people's

Язык: Английский

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COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis (Preprint)

Опубликована: Ноя. 21, 2023

The unprecedented emergence of the COVID-19 pandemic necessitated development and global distribution vaccines, making understanding vaccine acceptance hesitancy crucial to overcoming barriers vaccination achieving widespread immunization. This umbrella review synthesizes findings from systematic reviews meta-analyses provide insights into perceptions on across diverse populations regions. We conducted a literature search major databases identify meta-analysis that reported hesitancy. AMSTAR-2 (A Measurement Tool Assess Systematic Reviews) criteria were used assess methodological quality included reviews. Meta-analysis was performed using STATA 17 with random effect model. data synthesis is presented in table format via narrative. Our inclusion met by 78 published between 2021 2023. analysis revealed moderate rate 63% (95% CI 0.60%-0.67%) general population, significant heterogeneity (<i>I</i>² = 97.59%). Higher rates observed among health care workers individuals chronic diseases, at 64% 0.57%-0.71%) 69% 0.61%-0.76%), respectively. However, lower noted pregnant women, 48% 0.42%-0.53%), parents consenting for their children, 61.29% 0.56%-0.67%). pooled 32% 0.25%-0.39%) population. assessment 19 high-quality, 38 moderate-quality, 15 low-quality, 6 critically low-quality meta-analyses. presence globally, emphasizing necessity population-specific, culturally sensitive interventions clear, credible information dissemination foster acceptance. disparities accentuate need continuous research understand evolving address unique concerns needs populations, thereby aiding formulation effective inclusive strategies. PROSPERO CRD42023468363; https://tinyurl.com/2p9kv9cr

Язык: Английский

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