COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis

JMIR Public Health and Surveillance, Journal Year: 2024, Volume and Issue: 10, P. e54769 - e54769

Published: April 30, 2024

The unprecedented emergence of the COVID-19 pandemic necessitated development and global distribution vaccines, making understanding vaccine acceptance hesitancy crucial to overcoming barriers vaccination achieving widespread immunization.

Language: Английский

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COVID-19 Vaccination Acceptance Among the Diabetic Population in the Northwestern Region of Romania: Insights From an Autofill Survey

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: March 30, 2025

Language: Английский

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COVID-19 Vaccine Effectiveness and Risk Factors of Booster Failure in 480,000 Patients with Diabetes Mellitus: A Population-Based Cohort Study

Microorganisms, Journal Year: 2025, Volume and Issue: 13(5), P. 979 - 979

Published: April 24, 2025

To investigate the real-world effectiveness of COVID-19 vaccines in a large cohort patients with diabetes mellitus (DM), we analyzed all >18-year-old registered Brazilian nationwide surveillance database between February 2020 and 2023. The primary outcome interest was vaccine against death, evaluated using multivariate logistic regression models. Among 2,131,089 SIVEP-Gripe, 482,677 (22.6%) had DM. After adjusting for covariates, DM higher risk death than those without comorbidities (adjusted odds ratio [aOR] = 1.43, 95% CI, 1.39–1.47). For (72.7%, 70.5–74.7) (73.4%, 68.2–76.7), similar after booster dose. However, it reduced associated other (60.5%; 57.5–63.2). strongest factor failure omicron variant (aOR 27.8, 19.9–40.1). Our study revealed that provided robust protection individuals our findings underscore need to update develop tailored strategies diabetes, especially additional underlying conditions.

Language: Английский

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Anti-SARS-CoV-2 antibody levels predict outcome in COVID-19 patients with type 2 diabetes: a prospective cohort study

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: Oct. 26, 2023

Patients with type 2 diabetes (T2D) constitute one of the most vulnerable subgroups in COVID-19. Despite high vaccination rates, a correlate protection to advise strategies for novel SARS-CoV-2 variants concern and lower mortality this high-risk group is still missing. It further unclear what antibody levels provide whether pre-existing organ damage affects threshold. To address these gaps, we conducted prospective multicenter cohort study on 1152 patients COVID-19 from five hospitals. were classified by status. Anti-SARS-CoV-2-spike-antibodies, creatinine NTproBNP measured hospital admission. Pre-specified endpoints all-cause in-hospital-mortality, ICU admission, endotracheal intubation, oxygen administration. Propensity score matching was applied increase comparability. We observed significantly anti-SARS-CoV-2-spike-antibodies diabetic non-survivors compared survivors (mean, 95% CI 351BAU/ml, 106-595 vs. 1123, 968-1279, p < 0.001). Mortality risk increased two-fold each standard deviation-decrease (aHR 1.988, 1.229-3.215, = 0.005). T2D requiring administration, intubation admission had than those who did not (p 0.001, 0.046, 0.011). While worse outcomes non-diabetic patients, differences less pronounced propensity-score-matched patients. Anti-SARS-CoV-2 spike antibodies are inversely associated intensive care in-hospital Pre-existing comorbidities may have greater impact outcome status alone.

Language: Английский

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A Critical Review on the Long-term COVID-19 Impacts on Patients with Diabetes

The American Journal of Medicine, Journal Year: 2024, Volume and Issue: unknown

Published: March 1, 2024

Language: Английский

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Covid-19 vaccine hesitancy and its predictors among diabetic patients on follow-up at public hospitals in Nekemte Town, Western Ethiopia

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(7), P. e0305200 - e0305200

Published: July 8, 2024

Background Understanding and addressing the concerns of vaccine-hesitant individuals, including those with chronic diseases, is key to increasing vaccine acceptance uptake. However, in Ethiopia, there limited evidence on COVID-19 hesitancy predictor variables among diabetic patients. Hence, study aimed assess Covid-19 Vaccine Hesitancy Predictor Diabetic Patients Follow-Up at Public Hospitals Nekemte Town, Western Ethiopia. Method Facility based cross sectional was conducted 422 patients attending public hospitals Ethiopia between January, February, 2023. Study participants were recruited by systematic random sampling. The data collected interviewee administered pre-tested structured survey questioner. entered cleaned using Epi-Data software 4.6 version. analyzed SPSS. 25.0 Statical software. Descriptive statistics like frequency, mean percentage, binary logistic regression applied identify independent predictors association declared p-value 0.05. Result overall magnitude 15.2% (95% CI: 11.6–18.7). top three listed reasons for were: negative information about (32.90%), lack enough (21.80%), safety concern (19.40%). vaccination uptake diabetes independently influenced age 40–49 (Adjusted Odd Ratio [AOR] = 4.52(1.04–19.66)), having awareness (AOR 0.029(0.001–0.86)), a great deal trust development 0.028(0.002–0.52)), fear amount 0.05(0.003–0.79)) preparation, vaccinated 0.13(0.04–0.51)), perceived exposure infection after as strongly agree/agree 0.03(0.01–0.17))and neither agree nor disagree 0.07(0.02–0.30)). Conclusion relatively low. identified age, awareness, history, preparation status infection. relevant agency should focus efforts translating these high levels into actual uptake, through targeting identifying availability high-risk patient.

Language: Английский

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Examining the longitudinal effect of depressive symptoms on physical activity in persons with type 2 diabetes during the COVID-19 pandemic.

Mental health and physical activity, Journal Year: 2024, Volume and Issue: 27, P. 100647 - 100647

Published: Oct. 1, 2024

Language: Английский

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What factors affect acceptance attitudes towards vaccination amidst a major public health crisis? A national cross-sectional study

BMJ Open, Journal Year: 2024, Volume and Issue: 14(12), P. e088245 - e088245

Published: Dec. 1, 2024

Vaccine hesitancy persists as a significant global health concern, especially during public crises. This study aimed to explore factors influencing vaccination acceptance major crisis and establish model of factors.

Language: Английский

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Stress and quality of life among susceptible Thai people during COVID-19 pandemic

International Journal of Public Health Science (IJPHS), Journal Year: 2023, Volume and Issue: 12(4), P. 1687 - 1687

Published: Oct. 4, 2023

People with underlying disease (diabetes mellitus, and hypertension) could be stressed during COVID-19 pandemic. This study was investigated stress levels quality of life among diabetes mellitus and/or hypertension patients, factors related to in Khon Kaen cross-sectional analytical conducted 270 samples. Multilevel logistic regression performed identify the influence level (QoL). The results showed that most samples had a moderate (78.5%), high (3.3%). For overall QoL, it found them (77.8%), poor (7.8%). likelihood QOL 5.5 times (adj. OR=5.5; 95% CI: 1.6 18.1) income decreasing due economic downturn, no impact not immunized 3.4 OR=3.4; CI:1.2 9.2) statistical significance at 0.05 level. It concluded nearly 2.5–3 times, life, issues affected people's

Language: Английский

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COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis (Preprint)

Published: Nov. 21, 2023

The unprecedented emergence of the COVID-19 pandemic necessitated development and global distribution vaccines, making understanding vaccine acceptance hesitancy crucial to overcoming barriers vaccination achieving widespread immunization. This umbrella review synthesizes findings from systematic reviews meta-analyses provide insights into perceptions on across diverse populations regions. We conducted a literature search major databases identify meta-analysis that reported hesitancy. AMSTAR-2 (A Measurement Tool Assess Systematic Reviews) criteria were used assess methodological quality included reviews. Meta-analysis was performed using STATA 17 with random effect model. data synthesis is presented in table format via narrative. Our inclusion met by 78 published between 2021 2023. analysis revealed moderate rate 63% (95% CI 0.60%-0.67%) general population, significant heterogeneity (<i>I</i>² = 97.59%). Higher rates observed among health care workers individuals chronic diseases, at 64% 0.57%-0.71%) 69% 0.61%-0.76%), respectively. However, lower noted pregnant women, 48% 0.42%-0.53%), parents consenting for their children, 61.29% 0.56%-0.67%). pooled 32% 0.25%-0.39%) population. assessment 19 high-quality, 38 moderate-quality, 15 low-quality, 6 critically low-quality meta-analyses. presence globally, emphasizing necessity population-specific, culturally sensitive interventions clear, credible information dissemination foster acceptance. disparities accentuate need continuous research understand evolving address unique concerns needs populations, thereby aiding formulation effective inclusive strategies. PROSPERO CRD42023468363; https://tinyurl.com/2p9kv9cr

Language: Английский

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