Colloids and Surfaces B Biointerfaces, Год журнала: 2024, Номер 241, С. 114020 - 114020
Опубликована: Июнь 12, 2024
Язык: Английский
Chemical Society Reviews, Год журнала: 2024, Номер 53(12), С. 6399 - 6444
Опубликована: Янв. 1, 2024
This review highlights recent advances in immunological nanomaterials against metastasis and summarizes various nanomaterial-mediated immunotherapy strategies.
Язык: Английский
Процитировано
21
Pharmaceutics, Год журнала: 2024, Номер 16(5), С. 674 - 674
Опубликована: Май 16, 2024
The escalating demand for enhanced therapeutic efficacy and reduced adverse effects in the pharmaceutical domain has catalyzed a new frontier of innovation research field pharmacy: novel drug delivery systems. These systems are designed to address limitations conventional administration, such as abbreviated half-life, inadequate targeting, low solubility, bioavailability. As disciplines pharmacy, materials science, biomedicine continue advance converge, development efficient safe systems, including biopharmaceutical formulations, garnered significant attention both domestically internationally. This article presents an overview latest advancements categorized into four primary areas: carrier-based coupling-based targeted intelligent devices, based on their main objectives methodologies. Additionally, it critically analyzes technological bottlenecks, current challenges, future trends application
Язык: Английский
Процитировано
16
Biotechnology Advances, Год журнала: 2025, Номер 81, С. 108546 - 108546
Опубликована: Фев. 26, 2025
Язык: Английский
Процитировано
2
Coordination Chemistry Reviews, Год журнала: 2024, Номер 506, С. 215712 - 215712
Опубликована: Фев. 15, 2024
Язык: Английский
Процитировано
14
Ageing Research Reviews, Год журнала: 2024, Номер 95, С. 102241 - 102241
Опубликована: Фев. 21, 2024
Arthritis has become the most common joint disease globally. Current attention shifted towards preventing and exploring pharmaceutical surgical treatments for early-stage arthritis. M2 macrophages are known their anti-inflammatory properties ability to support cartilage repair, offering relief from Whereas, it remains a great challenge promote beneficial secretion of prevent progression Therefore, is warranted investigate new strategies that could use functions enhance its therapeutic effects. This review aims explore macrophage cell membrane-coated biomimetic nanovesicles targeted treatment arthritis such as osteoarthritis (OA), rheumatoid (RA), gouty (GA). Cell membrane-camouflaged nanovesicle attracted increasing attention, which successfully combine advantages both membrane delivered drug. We discuss roles in pathophysiology targets Then, preparation concluded. Moreover, we applications arthritis, OA, RA, GA. Taken together, hold tremendous prospect biomedical
Язык: Английский
Процитировано
9
Advanced Drug Delivery Reviews, Год журнала: 2024, Номер 207, С. 115194 - 115194
Опубликована: Фев. 10, 2024
Язык: Английский
Процитировано
9
Drug Discovery Today, Год журнала: 2024, Номер 29(6), С. 103991 - 103991
Опубликована: Апрель 23, 2024
The development of vaccines has had a crucial role in preventing and controlling infectious diseases on global scale. Innovative formulations biomimetic inspired by natural defense mechanisms combine long-term antigen stability, immunogenicity, targeted delivery with sustained release. Types nanoparticle (NP) include bacterial outer membrane vesicles (OMVs), cell membrane-decorated NPs, liposomes, exosomes. These approaches have shown potential for cancer immunotherapy, antibacterial antiviral applications. Despite current challenges, nanovaccines immense to transform disease prevention treatment, promising therapeutic the future. In this review, we highlight recent advances vaccine design, action, clinical applications, emphasizing their personalized medicine, drug delivery, immunomodulation.
Язык: Английский
Процитировано
9
Journal of Medicinal Chemistry, Год журнала: 2025, Номер unknown
Опубликована: Янв. 8, 2025
Oligonucleotides have emerged as a formidable new class of nucleic acid therapeutics. Fully modified oligonucleotides exhibit enhanced metabolic stability and display successful clinical applicability for targets formerly considered "undruggable". Accumulating studies show that conjugation to targeting modalities stabilized oligonucleotides, especially small interfering RNAs (siRNAs), has enabled robust delivery intended cells/tissues. However, the major challenge in field been targeted (siRNAs antisense (ASOs)) extrahepatic tissues. In this Perspective, we review chemistry innovations emerging approaches revolutionized oligonucleotide drug discovery development. We explore findings from both academia industry highlight potential indications involving different organs─including skeletal muscles, brain, lungs, skin, heart, adipose tissue, eyes. all, continued advances coupled with conjugation-based or novel administration routes will further advance
Язык: Английский
Процитировано
1
Journal of Materials Chemistry B, Год журнала: 2024, Номер 12(17), С. 4080 - 4096
Опубликована: Янв. 1, 2024
An illustrative depiction highlighting the targeted drug delivery mechanism by bio-functionalized camouflaged MOF nanocarriers that enhances precision targeting diseased cells and minimizing side effects.
Язык: Английский
Процитировано
7
Journal of Colloid and Interface Science, Год журнала: 2023, Номер 652, С. 770 - 779
Опубликована: Авг. 18, 2023
Язык: Английский
Процитировано
14