ACS Applied Polymer Materials,
Год журнала:
2024,
Номер
6(16), С. 9545 - 9558
Опубликована: Авг. 14, 2024
In
the
preservation
of
water-rich
foods,
especially
meat,
spoilage
can
occur
due
to
bacterial
contamination
and
oxidative
degradation.
This
study
aimed
determine
structural
characteristics
synthesis
chitosan-graft-pomegranate
extract
(CS-g-POM)
hydrogel
using
a
cost-effective
biobased
method
develop
antibacterial
antioxidant
pads.
Pomegranate
is
used
fabricate
covalently
noncovalently
interconnected
chitosan
networks.
Several
characterization
methods,
such
as
Fourier
transform
infrared
spectroscopy,
thermogravimetric
analysis,
field
emission
scanning
electron
microscopy,
atomic
force
rheological
confirmed
successful
design
produced
hydrogel.
The
freeze-dried
CS-g-POM
had
swelling
ratio
373%,
614%,
508.5%
at
pH
5,
7.4,
10,
respectively.
FE-SEM
images
showed
porous
hydrogel,
which
cross-linking
process.
addition
pomegranate
increased
phenolic
content,
resulting
in
DPPH
radical
scavenging
activity
50.20%.
also
good
properties,
with
inhibition
zones
against
Escherichia
coli
Staphylococcus
aureus
measuring
18
±
1
mm
12
mm.
plays
crucial
role
moisture
absorption
foods
meat
its
high
degree
could
be
an
pad.
Translational Oncology,
Год журнала:
2024,
Номер
45, С. 101975 - 101975
Опубликована: Апрель 30, 2024
Hepatocellular
carcinoma
(HCC)
is
the
most
prevalent
type
of
liver
cancer,
mainly
occurring
in
Asian
countries
with
an
increased
incidence
rate
globally.
Currently,
several
kinds
therapies
have
been
deployed
for
HCC
therapy
including
surgical
resection,
chemotherapy,
radiotherapy
and
immunotherapy.
However,
this
tumor
still
incurable,
requiring
novel
strategies
its
treatment.
The
nanomedicine
has
provided
new
insights
regarding
treatment
cancer
that
liposomes
as
lipid-based
nanoparticles,
widely
applied
due
to
their
biocompaitiblity,
high
drug
loading
ease
synthesis
modification.
current
review
evaluates
application
therapy.
drugs
genes
lack
targeting
ability
into
tissues
cells.
Therefore,
or
on
can
increase
accumulation
site
suppression.
Moreover,
stimuli-responsive
pH-,
redox-
light-sensitive
are
able
deliver
microenvironment
improve
therapeutic
index.
Since
a
number
receptors
upregulate
cells,
functionalization
lactoferrin
peptides
promote
towards
phototherapy
be
induced
by
through
phtoosensitizers
stimulate
photothermal-
photodynamic-driven
ablation
Overall,
findings
line
fact
promising
nanocarriers
HCC.
Abstract
Nonviral
vectors,
such
as
liposomes,
offer
potential
for
targeted
gene
delivery
in
cancer
therapy.
Liposomes,
composed
of
phospholipid
vesicles,
have
demonstrated
efficacy
nanocarriers
genetic
tools,
addressing
the
limitations
off‐targeting
and
degradation
commonly
associated
with
traditional
therapy
approaches.
Due
to
their
biocompatibility,
stability,
tunable
physicochemical
properties,
they
overcoming
challenges
therapy,
low
transfection
efficiency
poor
stability
biological
fluids.
Despite
these
advancements,
there
remains
a
gap
understanding
optimal
utilization
nanoliposomes
enhanced
treatment.
This
review
delves
into
present
state
carriers
tools
sheds
light
on
safeguard
payloads
facilitate
cell
internalization
alongside
evolution
smart
delivery.
The
linked
biocompatibility
factors
that
restrict
effectiveness
are
also
discussed
along
exploring
strategies
by
analyzing
recent
advancements
offering
future
directions.
Journal of Nanobiotechnology,
Год журнала:
2024,
Номер
22(1)
Опубликована: Сен. 18, 2024
Breast
cancer
(BC)
is
a
significant
health
challenge,
ranking
as
the
second
leading
cause
of
cancer-related
death
and
primary
mortality
among
women
aged
45
to
55.
Early
detection
crucial
for
optimal
prognosis.
Among
various
treatment
options
available
cancer,
chemotherapy
remains
predominant
approach.
However,
its
patient-friendliness
hindered
by
cytotoxicity,
adverse
effects,
multi-drug
resistance,
potential
recurrence,
high
costs.
This
review
explores
extensively
studied
phytomolecules,
elucidating
their
molecular
mechanisms.
It
also
emphasizes
importance
combination
therapy,
highlighting
recent
advancements
in
exploration
diverse
drug
delivery
systems
novel
routes
administration.
The
regulatory
considerations
are
translating
these
approaches
into
clinical
practices.
Polymers from Renewable Resources,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 8, 2025
The
use
of
conductive
hydrogels
in
flexible
electronics
has
gained
significant
attention
recent
years.
However,
the
performance
traditional
is
often
hindered
by
dehydration
at
elevated
temperatures
and
structural
rigidity
when
frozen
low
temperatures.
In
this
study,
we
developed
a
double-network
hydrogel
consisting
ionically
crosslinked
pectin
covalently
polyacrylamide
(PAAm)
networks.
Scanning
Electron
Microscopy
(SEM)
analysis
revealed
highly
interconnected
porous
microstructure,
which
contributes
to
enhanced
mechanical
strength
flexibility
hydrogel.
Through
solvent
exchange
process,
PAAm-pectin
was
transformed
into
an
organo-gel
immersing
it
binary
system
ethylene
glycol
water.
incorporation
significantly
improved
hydrogel’s
temperature
tolerance,
imparting
superior
anti-freezing
anti-drying
properties.
resulting
organogel
exhibited
remarkable
transparency,
excellent
flexibility,
sustained
ionic
conductivity
even
as
−40°C.
These
attributes
highlight
promising
candidate
for
next-generation
electronic
devices,
where
stability
under
extreme
conditions
essential.
Advanced Materials Interfaces,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 5, 2025
Abstract
A
remarkable
one‐third
of
global
food
production
is
wasted,
resulting
in
significant
economic
damage
and
escalating
insecurity.
To
address
this
sustainability
challenge,
freshness
identification
packaging
using
intelligent
materials
has
gained
traction.
This
work
introduces
a
chitosan‐
graft
‐gelatin
(CS‐g‐GEL)
hydrogel,
incorporating
pH‐responsive
dye,
bromothymol
blue
(BTB),
as
colorimetric
indicator
to
monitor
the
spoilage
chicken
breasts.
The
successful
formulation
hydrogels
verified
FTIR,
AFM,
SEM,
TGA,
1
HNMR
characterization
techniques.
At
pH
5
7.4,
swelling
capacity
hydrogel
790%
470%,
respectively.
rise
colony‐forming
units
(CFU)
from
5.5
on
day
1–7.4
log
CFU
g
−1
7
indicate
microbial
activity,
carbon
dioxide
due
deteriorating
decreases
package.
Additionally,
CO
2
concentrations
3.2
1–22.1
(%
v/v)
7,
while
O
levels
23.8
near
0.5
same
period.
developed
demonstrated
serve
smart
visual
offers
new
dimension
use
toward
challenge.
