Exercise Interventions for Depression, Anxiety, and Quality of Life in Older Adults With Cancer

JAMA Network Open, Год журнала: 2025, Номер 8(2), С. e2457859 - e2457859

Опубликована: Фев. 4, 2025

Importance Cancer and its treatment negatively impact the mental health of older adults. The potential exercise interventions as a complementary to alleviate psychological impacts cancer is promising, but there are gaps in current literature. Objective To determine if associated with improvements outcomes among adults cancer. Data Sources PubMed, Embase, PsycINFO, Cochrane databases were searched from database inception November 5, 2024. Search terms used geriatrics , depression anxiety quality life . Study Selection English-language randomized clinical trials (RCTs) that analyzed association various at least 1 3 (depression, anxiety, or health-related quality-of-life [HRQOL]) included. control groups given usual care. Studies included mean age participants was than 60 years had diagnosis any regardless comorbidities. Extraction Synthesis screened, data extracted by 2 independent authors. Random-effects meta-analyses meta-regressions for analysis. Preferred Reporting Items Systematic Reviews Meta-Analyses guideline followed. Main Outcomes Measures primary depression, HRQOL. Standardized difference (SMD) quantify outcomes. Results A total 27 RCTs 1929 Meta-analyses observed an significant reduction levels (SMD = −0.53; 95% CI, −0.79 −0.28) −0.39; −0.66 −0.12) overall HRQOL 0.63; 0.10 1.17). Subgroup analyses revealed mind-body significantly improved −0.89; −1.51 −0.27) −0.77; −1.54 −0.01) compared conventional interventions. Conclusion In this systematic review meta-analysis RCTs, found be reduced These findings suggest care professionals policymakers should focus more on implementing improve vulnerable population.

Язык: Английский

---

Prevalence and incidence of suicide, suicidal ideation and self-harm in caregivers of cancer patients: A systematic review and meta-analysis

General Hospital Psychiatry, Год журнала: 2024, Номер 90, С. 35 - 43

Опубликована: Июнь 21, 2024

Язык: Английский

---

Suicide and Suicidal Ideation Among Survivors of Childhood Cancer

JAMA Network Open, Год журнала: 2025, Номер 8(2), С. e2457544 - e2457544

Опубликована: Фев. 17, 2025

Importance Reliable estimates of the prevalence and risk suicide suicidal ideation (SI) among childhood cancer survivors (CCSs) are crucial in informing efforts to address this issue. Objective To systematically evaluate SI CCSs. Data Sources A literature search was conducted PubMed, Embase, Cochrane Library, PsycINFO from January 1, 2000, November 17, 2024. Study Selection All noncontrolled controlled studies that evaluated drew comparisons between CCSs their counterparts. Studies including participants older than 25 years, no reported outcomes, case studies, reviews, review articles were excluded. Extraction Synthesis The Preferred Reporting Items for Systematic Reviews Meta-analyses reporting guideline followed with prospective PROSPERO registration. Prevalence pooled single-arm studies. Relative ratio (RR) double-arm Metaprop used meta-analyze under a generalized linear mixed model. For dichotomous meta-analyses performed compute RR psychological outcome compared controls. Main Outcomes Measures SI, controls, factors associated suicidality outcomes. Results From 531 records, 16 included. on included 148 869 20 140 participants. 0.30% (0.13%-0.69%) 9% (95% CI, 7%-11%). There significantly increased controls (RR, 1.67 [95% Cl, 1.39-2.01]), but not 1.50 0.63-3.62]). Subgroup analyses suggested is much higher during active period years after (proportion, 0.14 0.10-0.19] vs 0.08 0.06-0.09]). systematic identified preexisting mental illness, poor physical health, age, male sex, being single as Conclusions Relevance In meta-analysis CCSs, different had SI. Future needed explore outcomes guide targeted support policies.

Язык: Английский

---

Comparing loss of contractual employment pre- and post-diagnosis in patients with rare versus common cancer types: a national registry-based study

Journal of Cancer Survivorship, Год журнала: 2025, Номер unknown

Опубликована: Янв. 6, 2025

Язык: Английский

---

What do patients with a rare cancer living in rural, regional or remote areas and stakeholders want from a peer support program? A qualitative study

BMC Cancer, Год журнала: 2025, Номер 25(1)

Опубликована: Фев. 25, 2025

Abstract Background Patients with a rare cancer in rural, regional, and remote Australia experience heightened challenges their illness journey, including significant psychosocial impacts. Although peer support has shown benefits for common patients living urban areas, these programs often do not reach underserved groups instance those cancer, or regional areas. This study aimed to explore the characteristics of Methods Focus interviews were conducted 39 people 10 healthcare providers key points inclusion service diagnosed Data transcribed verbatim analysed thematically, using Nvivo. Results Participants described needs terms who, what, how, where, when. advocated flexible, multicomponent intervention that could meet varied fluctuating this group. also noted practical delivery such service, specifically, risk receiving misinformation, adverse emotional reactions, interpersonal implementation issues. Conclusions highlights role addressing unmet particularly rural emphasising importance tailored, multimodal interventions addresses diverse needs.

Язык: Английский

---

Burden of psychological symptoms and disorders among individuals with hepatitis B: a systematic review, meta-analysis and meta-regression

Frontiers in Psychiatry, Год журнала: 2025, Номер 16

Опубликована: Март 24, 2025

Introduction Hepatitis B is a highly contagious viral infection that has long been significant global health concern. Given its adverse effects on the course of disease, evaluating psychiatric outcomes important. Despite indications an increased risk psychological among those with hepatitis B, extent this association remains unclear. Methods This PRISMA-adherent systematic review (PROSPERO: CRD42024564246) searched PubMed, Embase, Cochrane, and PsycINFO for all studies prevalence anxiety depressive symptoms in individuals B. Random meta-analyses meta-regression were used primary analysis. Results A total 31 included. We identified high (Proportion=19%, 95% CI: 11-31) (Proportion=30%, 18-45) There was also significantly (RR=1.45, 1.00-2.09, P=0.049) (RR=1.40, 1.11-1.78) compared to controls. Subgroup analyses indicated older age chronic associated higher symptoms. The found being single, unemployed, having lower income, education level, comorbidities, family history mental illness factors poorer outcomes. Conclusion Our study highlights vulnerability emphasize urgent need early detection additional support at-risk group. Systematic registration https://www.crd.york.ac.uk/prospero/ , identifier CRD42024564246.

Язык: Английский

---

Analysis of anxiety and depression and influencing factors in non-Hodgkin's lymphoma of the nasal cavity and paranasal sinus

World Journal of Psychiatry, Год журнала: 2025, Номер 15(4)

Опубликована: Март 25, 2025

BACKGROUND Natural killer (NK)/T-cell non-Hodgkin's lymphoma (NHL) in the nasal cavities and paranasal sinuses accounts for approximately 10% of all lymphomas, occurrence NHL is related to Epstein-Barr virus infection. AIM To explore anxiety depression status patients with NK/T-cell analyzes relevant influencing factors. METHODS A retrospective analysis was performed, which included 30 primary treated Shaanxi Provincial People’s Hospital from January 2017 2023. An additional 50 healthy volunteers were selected as control group. Both groups assessed using self-rating scale (SAS) Self-rating (SDS). SDS SAS scores at different disease stages analyzed, they further grouped into negative emotion (NE) (n = 19) non-NE 11) based on their anxiety. Factors affecting NEs analyzed univariate multivariate logistic regression models. RESULTS Patients exhibited higher than controls. Moreover, III IV had those stage I. Among patients, there 13 (43.3%), 16 (53.3%), 10 both (33.3%). Univariate identified a proportion people NE group III-IV NHL, an educational level ≤ high school, monthly household income < 5000 yuan compared Multiple revealed that risk factor NHL. CONCLUSION The closely patient depression. staging, greater incidence

Язык: Английский

---

Optimal and minimal doses of metacognitively oriented treatments on mental health outcomes: a pioneering meta-analysis

Current Psychology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 4, 2025

Язык: Английский

---

Effectiveness of immune checkpoint inhibitors and other treatment modalities in patients with advanced mucosal melanomas: a systematic review and individual patient data meta-analysis

EClinicalMedicine, Год журнала: 2024, Номер 77, С. 102870 - 102870

Опубликована: Окт. 4, 2024

Язык: Английский

---

Vitamin, antioxidant and micronutrient supplementation and the risk of developing incident autoimmune diseases: a systematic review and meta-analysis

Frontiers in Immunology, Год журнала: 2024, Номер 15

Опубликована: Дек. 9, 2024

Autoimmune diseases pose significant health challenges worldwide and affect millions. In recent years, there has been growing interest in exploring preventive strategies through nutritional interventions using vitamins, antioxidants, micronutrients to reduce the risk of developing autoimmune diseases. However, excessive supplementation also associated with toxicity.

Язык: Английский

---