A Systematic Review of Participant Diversity in Psychedelic-Assisted Psychotherapy Trials
Psychiatry Research,
Год журнала:
2025,
Номер
345, С. 116359 - 116359
Опубликована: Янв. 11, 2025
Язык: Английский
Psychedelic-assisted therapy for treating anxiety, depression, and existential distress in people with life-threatening diseases
Cochrane library,
Год журнала:
2024,
Номер
2024(9)
Опубликована: Сен. 12, 2024
Язык: Английский
Enhanced independence: De-biasing processes in psychedelic research and beyond
Research Ethics,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 2, 2025
Randomized
controlled
trials
(RCTs)
are
considered
the
gold
standard
for
demonstrating
efficacy
of
a
treatment
or
intervention;
however,
RCT
study
design
alone
is
insufficient
to
prevent
all
forms
bias.
In
this
paper,
we
review
conflicts
interest
and
other
biases
that
pose
challenges
methodological
rigor
psychedelic
RCTs,
explore
recommended
bias
mitigation
measures.
We
focus
on
special
relevance
RCTs
methods
mitigating
believe
actionable
urgent
practices
implement
in
research:
(1)
independent
data
assessment,
(2)
multisite
trials,
(3)
quantitative
analysis,
(4)
open
science
practices.
Although
advocate
adoption
these
research,
they
not
specific.
suggest
posed
by
research
offer
an
opportunity
researchers
creatively
find
solutions
across
lifecycle
reduce
fields
clinical
research.
Язык: Английский
Acute subjective effects of psychedelics in naturalistic group settings prospectively predict longitudinal improvements in trauma symptoms, trait shame, and connectedness among adults with childhood maltreatment histories
Progress in Neuro-Psychopharmacology and Biological Psychiatry,
Год журнала:
2025,
Номер
unknown, С. 111361 - 111361
Опубликована: Апрель 1, 2025
Studies
of
psychedelic
use
in
naturalistic
and
clinical
settings
have
suggested
safety
mental
health
benefits
for
adults
with
histories
childhood
maltreatment.
Acute
psychological
mechanisms
that
predict
therapeutic
this
population,
however,
yet
to
be
determined.
Two
common
group
-
organized
ceremonies
raves
or
other
electronic
dance
music
events
might
facilitate
effects
because
the
unique
psychosocial
environments
they
comprise.
This
prospective,
longitudinal
study
sought
investigate
2
primary
questions:
first,
whether
maltreatment
planning
drugs
intent
at
would
see
enduring
after
their
experiences;
second,
subjective
dimensions
acute
experience
associated
lasting
benefits.
Eighty-five
participants
completed
self-report
measures
month
before,
within
days
after,
approximately
months
a
planned
ceremony
rave
assessing
history;
trauma
symptoms,
internalized
(trait)
shame,
connectedness
baseline
follow-up;
various
experience.
Mean
scores
posttraumatic
stress
disorder
(PTSD)
complex
PTSD
trait
social
connectedness,
general
significantly
improved
from
2-month
follow-up
(ds
=
0.73-1.12).
Longitudinal
changes
outcomes
correlated
These
findings
implications
regarding
both
potential
benefit
among
as
well
action
psychedelics.
Язык: Английский
Racial Differences in Naturalistic Psychedelic Use — Motivations for Use, Communication with Health Care Providers, and Outcomes
Journal of Psychoactive Drugs,
Год журнала:
2025,
Номер
unknown, С. 1 - 12
Опубликована: Апрель 22, 2025
People
of
Color
have
been
under-included
in
psychedelic-assisted
therapy
(PAT)
research.
Researchers
argued
that
systemic
issues
resulting
harms
to
communities
color
like
the
War
on
Drugs
and
recurrent
exposure
discrimination
healthcare
settings
may
reduce
their
willingness
engage
PAT
However,
there
are
no
empirical
data
regarding
Color's
trust
or
using
psychedelics
with
support
trained
providers.
Therefore,
we
analyzed
from
a
large-scale
survey
people
explore
interactions
between
providers
North
America.
The
sample
included
3,547
White
people,
448
Color,
377
Multiracial
people.
A
lower
proportion
consumed
provider
but
an
equal
had
disclosed
psychedelic
use
primary
care
Further,
were
equally
motivated
provider,
used
treat
similar
issues,
similarly
reported
as
effective
other
groups.
Our
findings
suggest
lack
not
fully
explain
underrepresentation
research,
future
studies
should
investigate
barriers
inclusion
Язык: Английский
Patterns of Internalizing Problems, Substance Use and Cognitive Flexibility Before and After Naturalistic Psilocybin Use: A Repeated Measures Latent Profile Analysis
International Journal of Mental Health and Addiction,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 24, 2025
Язык: Английский
Knowledge, attitudes, and concerns about psilocybin and MDMA as novel therapies among U.S. healthcare professionals
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Ноя. 14, 2024
Abstract
Psychedelic-assisted
therapy
(PAT)
with
substances
like
psilocybin
and
MDMA
has
shown
promise
for
conditions
including
depression
post-traumatic
stress
disorder.
Psilocybin
may
become
approved
medicines
in
the
coming
decade.
This
study
assessed
knowledge
attitudes
regarding
PAT
among
879
U.S.
healthcare
professionals
via
anonymous
online
survey.
Multivariable
linear
regression
was
used
to
identify
predictors
of
openness
clinical
use.
Most
participants
(71.2%)
were
female
White
(85.8%),
a
mean
(SD)
age
45.5
(12.7)
years.
Registered
nurses
(25.4%)
physicians
(17.7%)
comprised
largest
professional
groups.
Respondents
endorsed
strong
belief
therapeutic
promise,
moderate
use
support
legal
access
both
substances,
higher
overall
ratings
compared
MDMA.
Objective
items
revealed
low
uses,
risks,
pharmacology.
Primary
concerns
lack
trained
providers,
financial
cost,
potential
contraindications.
Prior
psychedelic
use,
self-rated
knowledge,
younger
age,
role
predicted
MDMA,
reporting
lower
openness.
As
psychedelics
continue
garner
popular
scientific
interest,
results
indicate
pressing
need
additional
formal
training
provide
balanced,
evidence-based
information
from
trusted
sources.
Язык: Английский
Examining differences in the effects and contexts of naturalistic psilocybin use for White participants vs. participants of Color: A longitudinal online survey study
Journal of Affective Disorders,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 1, 2024
Язык: Английский
A Systematic Review of Participant Diversity in Psychedelic-Assisted Psychotherapy Trials
Опубликована: Авг. 25, 2024
Limited
participant
diversity
in
mental
health
intervention
research
perpetuates
disparities.
This
issue
has
become
a
particularly
salient
concern
studies
of
psychedelic-assisted
psychotherapy
(PAT),
which
is
emerging
as
promising
intervention.
systematic
review
evaluates
the
reporting,
representation,
and
analysis
sociodemographic
characteristics
randomized
controlled
trials
(RCTs)
PAT.
A
total
21
RCTs
psilocybin-
3,4-methylenedioxy
methamphetamine
(MDMA)-assisted
therapies
(N
=
1034)
are
summarized.
Participants’
gender
(100%)
race
or
ethnicity
(76%)
were
frequently
reported,
with
socioeconomic
status
(SES)
sometimes
(57%)
reported
using
heterogeneous
metrics.
Sexual
orientation
(9.5%)
immigration
(4.8%)
rarely
no
identity.
Compared
to
their
representation
US
population
non-psychedelic
clinical
trials,
Black/African-American
participants
(12.2%)
Hispanic/Latino
(7.2%)
significantly
underrepresented
PAT
RCTs.
MDMA
enrolled
more
diverse
samples
than
psilocybin
trials.
Analyses
on
treatment
effects
based
variables
virtually
nonexistent.
These
findings
underscore
need
for
inclusive
recruitment
strategies,
along
rigorous
reporting
analytic
practices,
improve
generalizability
research.
Язык: Английский
Reading the crowd: attitudes toward psychedelics and psychedelic therapies among attendees at a conference
Psychedelics.,
Год журнала:
2024,
Номер
unknown, С. 1 - 7
Опубликована: Дек. 17, 2024
Social
attitudes,
policy,
and
perceptions
of
psychedelics
are
currently
undergoing
considerable
change.
Growing
public
salience
has
been
accompanied
by
the
emergence
conferences
focused
on
psychedelic
education
dialogue.
Attendees
at
such
events
compose
an
important
group
stakeholders
in
science
practice;
their
views
can
be
valuable
for
understanding
current
status
this
emerging
field.
For
study,
a
survey
was
administered
to
attendees
(
N
=
178)
academic
conference
two
topics:
spiritual
care.
The
queried
attitudes
toward
research
domains:
1)
potential
benefits
microdosing
2)
harm
with
use.
A
subset
who
were
facilitators
care
n
32)
also
asked
about
facilitation
practices
beliefs
concerning
aspects
facilitation.
Participants
generally
agreed
that
may
have
(M
3.90,
where
4
Probably,
SD
0.95)
modest
concern
(40.2%
72)
or
strongly
30.7%
55)
respondents
“not
sure”)
could
harmful
when
used
therapeutically.
Descriptive
analyses
characterized
harms
observed
during
Psychedelic
reported
they
treat
wide
range
diagnoses,
employing
diverse
psychotherapy
modalities,
endorsed
need
cultural
adaptations
among
treatments.
Язык: Английский