Antibiotics in the environment: causes and consequences

Medicine and Pharmacy Reports, Год журнала: 2020, Номер unknown

Опубликована: Июль 29, 2020

Antibiotics represent one of the main discoveries last century that changed treatment a large array infections in significant way. However, increased consumption has led to an exposure bacterial communities and ecosystems amount antibiotic residues. This paper aims provide brief overview primary drivers associated with occurrence environment. Furthermore, we attempted summarize behavior residues environment necessity their detection quantification. Also, updated scientific regulatory facts about environmental discharge human antibiotics risk assessment. We propose contamination should be diminished beginning from regulating causes (such as consumption) ending assessment. Some important intermediate steps are represented by quantification characterization environment, which could come support future decisions.

Язык: Английский

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Antibiotics in surface water of East and Southeast Asian countries: A focused review on contamination status, pollution sources, potential risks, and future perspectives

The Science of The Total Environment, Год журнала: 2020, Номер 764, С. 142865 - 142865

Опубликована: Окт. 9, 2020

Язык: Английский

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Origin of Antibiotics and Antibiotic Resistance, and Their Impacts on Drug Development: A Narrative Review

Pharmaceuticals, Год журнала: 2023, Номер 16(11), С. 1615 - 1615

Опубликована: Ноя. 15, 2023

Antibiotics have revolutionized medicine, saving countless lives since their discovery in the early 20th century. However, origin of antibiotics is now overshadowed by alarming rise antibiotic resistance. This global crisis stems from relentless adaptability microorganisms, driven misuse and overuse antibiotics. article explores subsequent emergence It delves into mechanisms employed bacteria to develop resistance, highlighting dire consequences drug including compromised patient care, increased mortality rates, escalating healthcare costs. The elucidates latest strategies against drug-resistant encompassing innovative approaches such as phage therapy, CRISPR-Cas9 technology, exploration natural compounds. Moreover, it examines profound impact resistance on development, rendering pursuit new economically challenging. limitations challenges developing novel are discussed, along with hurdles regulatory process that hinder progress this critical field. Proposals for modifying facilitate development presented. withdrawal major pharmaceutical firms research examined, potential re-engage interest. also outlines initiatives overcome economic incentivize emphasizing international collaborations partnerships. Finally, sheds light government-led a specific focus Middle East. discusses proactive measures taken governments region, Saudi Arabia United Arab Emirates, combat threat. In face multifaceted approach imperative. provides valuable insights complex landscape challenges, collaborative efforts required ensure future where remain effective tools safeguarding public health.

Язык: Английский

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Application of advanced oxidation processes followed by different treatment technologies for hospital wastewater treatment

Journal of Cleaner Production, Год журнала: 2020, Номер 269, С. 122411 - 122411

Опубликована: Май 31, 2020

Язык: Английский

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Emerging contaminants as global environmental hazards. A bibliometric analysis

Emerging contaminants, Год журнала: 2020, Номер 6, С. 179 - 193

Опубликована: Янв. 1, 2020

This paper presents a bibliometric analysis of peer-reviewed scientific literature on emerging contaminants published from 2000 through 2019. A total 4968 documents (among research articles and review papers) collected Scopus database were analyzed using the VOSviewer 1.6.11 software. According to our results, this topic has been capturing researchers' attention over years latter five timespan corresponds period highest productivity subject, when 70.4% all published. United States, China, Spain, Italy Canada top–5 most productive countries in terms number works, while Science Total Environment, Chemosphere, Environmental Pollution Research, Water Research stood out as journals with publications, gathering 31% papers 34% citations. frequency author keywords, main specific assessed by researchers are occurrence pharmaceuticals personal care products wastewater removal such pollutants application adsorption advanced oxidation processes.

Язык: Английский

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Occurrence of antibiotics and bacterial resistance genes in wastewater: resistance mechanisms and antimicrobial resistance control approaches

World Journal of Microbiology and Biotechnology, Год журнала: 2022, Номер 38(9)

Опубликована: Июль 4, 2022

Abstract Antimicrobial pharmaceuticals are classified as emergent micropollutants of concern, implying that even at low concentrations, long-term exposure to the environment can have significant eco-toxicological effects. There is a lack standardized regulatory framework governing permissible antibiotic content for monitoring environmental water quality standards. Therefore, indiscriminate discharge antimicrobials potentially active concentrations into urban wastewater treatment facilities rampant. Antimicrobials may exert selective pressure on bacteria, leading resistance development and eventual health consequences. The emergence clinically important multiple antibiotic-resistant bacteria in untreated hospital effluents plants (WWTPs) has been linked continuous antimicrobials. levels antibiotics their correlation evolution spread resistant need be elucidated help formulation mitigation measures. This review explores frequently detected gives comprehensive coverage bacterial mechanisms different classes through expression wide variety genes either inherent and/or exchanged among or acquired from reservoir (ARGs) systems. To complement removal ARGs WWTPs, upscaling implementation prospective interventions such vaccines, phage therapy, natural compounds alternatives widespread use provides multifaceted approach minimize antimicrobial resistance.

Язык: Английский

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A stick-like intelligent multicolor nano-sensor for the detection of tetracycline: The integration of nano-clay and carbon dots

Journal of Hazardous Materials, Год журнала: 2021, Номер 413, С. 125296 - 125296

Опубликована: Фев. 5, 2021

Язык: Английский

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Antibiotic resistance in aquaculture and aquatic organisms: a review of current nanotechnology applications for sustainable management

Environmental Science and Pollution Research, Год журнала: 2022, Номер 29(46), С. 69241 - 69274

Опубликована: Авг. 15, 2022

Язык: Английский

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Chemical Fate and Partitioning Behavior of Antibiotics in the Aquatic Environment—A Review

Environmental Toxicology and Chemistry, Год журнала: 2021, Номер 40(12), С. 3275 - 3298

Опубликована: Авг. 11, 2021

Abstract Antibiotics in the aquatic environment is a major problem because of emergence antibiotic resistance. The long‐term ecological impact on unknown. Many sources allow entry antibiotics into environment, including wastewater‐treatment plants (WWTPs), agricultural runoff, hospital effluent, and landfill leachate. Concentrations vary significantly; studies have shown fluoroquinolones, tetracycline, macrolides, sulfonamides, penicillins to reach 2900, 1500, 9700, 21 400, 1600 ng L –1 wastewater effluent samples, respectively. However, concentrations are highly variable between different countries depend several factors seasonal variation, prescription, WWTP operating procedures. Likewise, reported that cause environmental effects greatly antibiotics, even within same class; however, this predicted concentration for considered was frequently <1000 ngL , indicating when discharged along with treated these potentially detrimental effect environment. generally quite hydrophilic nature; they can ionize form charged structures, such as cations, zwitterions, anions. Certain classes, particularly fluoroquinolones tetracyclines, adsorb onto solid matrices, soils, sediment, sludge, making it difficult fully understand their chemical fate adsorption coefficient ( K d ) varies classes tetracyclines showing highest values. values sulfonamides been 54 600, 7600, 130, 1.37 kg Factors pH matrix (sediment/soil sludge), ionic strength influence ; therefore, exist literature compound. Environ Toxicol Chem 2021;40:3275–3298. © 2021 SETAC

Язык: Английский

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Application of TiO2-Based Photocatalysts to Antibiotics Degradation: Cases of Sulfamethoxazole, Trimethoprim and Ciprofloxacin

Catalysts, Год журнала: 2021, Номер 11(6), С. 728 - 728

Опубликована: Июнь 12, 2021

The extensive application of antibiotics in human and veterinary medicine has led to their widespread occurrence a natural aquatic environment. Global health crisis is associated with the fast development antimicrobial resistance, as more infectious diseases cannot be treated than once. Sulfamethoxazole, trimethoprim ciprofloxacin are most commonly detected water systems worldwide. persistent toxic nature these makes elimination by conventional treatment methods at wastewater plants almost impossible. advanced oxidation processes heterogeneous photocatalysis over TiO2-based materials promising solution. This highly efficient technology potential sustainable, cost-efficient energy-efficient. A comprehensive review on various photocatalysts for degradation sulfamethoxazole, focused highlighting photocatalytic performance under reaction conditions (different amounts pollutant photocatalyst, pH, light source, media, presence inorganic ions, organic matter, oxidants). Mineralization efficiency ecotoxicity final products have been also considered. Further research needs presented based literature findings. Among them, design sunlight, stable, recyclable cost-effective materials; usage real wastewaters tests; compulsory assessment important tasks order meet requirements industrial application.

Язык: Английский

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