Advanced strategies in 3D bioprinting for vascular tissue engineering and disease modelling using smart bioinks
Joeng Ju Kim,
Dong‐Woo Cho
Virtual and Physical Prototyping,
Год журнала:
2024,
Номер
19(1)
Опубликована: Авг. 30, 2024
Advanced
three-dimensional
(3D)
bioprinting
technology
enables
the
precise
production
of
complex
vascular
structures
and
biomimetic
models,
driving
advancements
in
tissue
engineering
disease
mechanism
research.
At
core
this
is
smart
bioink,
which
suitable
for
fabricating
models
that
can
be
vascularised
to
meet
property
requirements
various
tissues.
Examples
bioinks
include
decellularized
extracellular
matrix
(dECM),
photocrosslinkable,
reversible,
microgel-based
biphasic
(MB)
bioinks,
whose
mechanical
properties
tuned
through
external
stimuli.
This
tuning
helps
generate
high-resolution
complex-shaped
networks
essential
cell
survival
functional
maturation.
review
explores
advanced
3D
strategies
using
spatially
controlled
perfusable
vitro
emphasising
reconstruction
within
bioprinted
models.
It
also
discusses
challenges
future
prospects,
suggesting
could
serve
as
alternatives
traditional
animal
modelling
drug
screening.
Язык: Английский
The cutting‐edge progress in bioprinting for biomedicine: principles, applications, and future perspectives
MedComm,
Год журнала:
2024,
Номер
5(10)
Опубликована: Сен. 23, 2024
Bioprinting
is
a
highly
promising
application
area
of
additive
manufacturing
technology
that
has
been
widely
used
in
various
fields,
including
tissue
engineering,
drug
screening,
organ
regeneration,
and
biosensing.
Its
primary
goal
to
produce
biomedical
products
such
as
artificial
implant
scaffolds,
tissues
organs,
medical
assistive
devices
through
software-layered
discrete
numerical
control
molding.
Despite
its
immense
potential,
bioprinting
still
faces
several
challenges.
It
requires
concerted
efforts
from
researchers,
engineers,
regulatory
bodies,
industry
stakeholders
are
principal
overcome
these
challenges
unlock
the
full
potential
bioprinting.
This
review
systematically
discusses
principles,
applications,
future
perspectives
while
also
providing
topical
overview
research
progress
over
past
two
decades.
The
most
recent
advancements
comprehensively
reviewed
here.
First,
printing
techniques
methods
summarized
along
with
related
bioinks
supporting
structures.
Second,
interesting
representative
cases
regarding
applications
biosensing
introduced
detail.
Finally,
remaining
suggestions
for
directions
proposed
discussed.
one
areas
fields.
aims
devices.
perspectives,
which
provides
description
Язык: Английский
Biofabricated tissue model for determining biocompatibility of metallic coatings
Biomaterials Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
A
biofabricated
3D
in
vitro
model
merges
MEW
scaffolds
with
the
GelMa
hydrogel
to
assess
biocompatibility
and
antibacterial
effects
of
metallic
coatings.
Nb,
Ta,
Ti,
Zr
enhance
cellular
activity.
Ag
W
show
strong
properties.
Язык: Английский
The rise of 3D bioprinting: from organs to personalized medicine
Patient-Oriented Medicine and Pharmacy,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 7, 2025
Bioprinting
has
emerged
as
a
groundbreaking
technology
in
the
realms
of
organ
transplantation
and
regenerative
medicine,
addressing
critical
challenges
such
shortages
tissue
repair.
This
review
explores
technological
advancements
innovations
bioprinting,
highlighting
state-of-the-art
techniques,
bioinks,
applications
engineering.
Key
milestones
printing
functional
tissues,
including
vascularized
transplantable
prototypes,
are
discussed
alongside
role
bioprinting
personalized
where
patient-oriented
models
revolutionizing
drug
testing
therapeutic
strategies.
Furthermore,
this
article
examines
ethical
considerations
associated
with
offering
insights
into
its
future
potential
to
transform
global
healthcare.
Язык: Английский
Natural macromolecule-based bioinks for 3D bioprinting: A systematic review of composition, physicochemical characterization, and biomedical applications
Tatiana Muñoz-Castiblanco,
Juan P. Moreno-Marín,
Marlon Osorio
и другие.
Bioprinting,
Год журнала:
2025,
Номер
unknown, С. e00407 - e00407
Опубликована: Март 1, 2025
Язык: Английский
Improving tumor microenvironment assessment in chip systems through next-generation technology integration
Frontiers in Bioengineering and Biotechnology,
Год журнала:
2024,
Номер
12
Опубликована: Сен. 25, 2024
The
tumor
microenvironment
(TME)
comprises
a
diverse
array
of
cells,
both
cancerous
and
non-cancerous,
including
stromal
cells
immune
cells.
Complex
interactions
among
these
play
central
role
in
driving
cancer
progression,
impacting
critical
aspects
such
as
initiation,
growth,
invasion,
response
to
therapy,
the
development
drug
resistance.
While
targeting
TME
has
emerged
promising
therapeutic
strategy,
there
is
need
for
innovative
approaches
that
accurately
replicate
its
complex
cellular
non-cellular
interactions;
goal
being
develop
targeted,
personalized
therapies
can
effectively
elicit
anti-cancer
responses
patients.
Microfluidic
systems
present
notable
advantages
over
conventional
Язык: Английский
Ophthalmologic Implications of Connective Tissue Diseases: A Comprehensive Review of Current Knowledge and Innovations
Cureus,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 17, 2024
Connective
tissue
diseases
(CTDs),
including
rheumatoid
arthritis
(RA),
systemic
lupus
erythematosus
(SLE),
Sjögren's
syndrome,
and
sclerosis
(SSc),
represent
a
diverse
group
of
disorders
characterized
by
abnormalities
in
the
proteins
that
support
tissues
organs.
These
can
affect
multiple
organ
systems
are
often
associated
with
significant
morbidity
mortality.
The
eyes
frequently
affected
among
various
involved,
ocular
manifestations
ranging
from
benign
conditions
such
as
dry
eye
syndrome
to
severe,
sight-threatening
complications
like
scleritis,
retinal
vasculitis,
optic
neuritis.
Recognizing
managing
these
ophthalmologic
implications
is
crucial
for
preventing
severe
complications,
providing
diagnostic
clues,
improving
patients'
quality
life.
This
comprehensive
review
aims
elucidate
current
knowledge
innovations
related
CTDs.
It
details
major
CTDs,
explores
approaches
identifying
differentiating
conditions,
discusses
management
strategies,
pharmacological
surgical
interventions.
Additionally,
highlights
recent
advancements
emerging
therapies
diagnosing
treating
CTD-related
conditions.
also
addresses
this
field's
challenges
future
directions,
emphasizing
importance
interdisciplinary
collaboration
continuous
research.
By
synthesizing
latest
research
clinical
insights,
seeks
enhance
understanding
healthcare
professionals
regarding
interplay
between
CTDs
health,
ultimately
contributing
improved
patient
care
outcomes.
Язык: Английский
A Review of Bioink Development for 3D Bioprinting: Application in Corneal Tissue Regeneration
Deleted Journal,
Год журнала:
2024,
Номер
3(2), С. 113 - 119
Опубликована: Дек. 30, 2024
This
review
was
to
describe
the
state
and
progress
regarding
methods
for
3D
bioprinting
applicable
corneal
regeneration;
these
are
identified
with
developments
related
bioink
technologies.
article
has
pointed
out
in
detail
mechanism
of
printing
process;
it
maintains
that
ideally
consists
biomaterial
components
deriving
both
from
natural
synthetic
ones,
cells,
biochemical
factors,
such
ways
which
could
imitate
properties
a
native
cornea
several
respects,
its
mechanic,
structural,
ultrastructural
features.
Biocompatibility,
transparency,
strength
tension,
corresponding
rheology
were
emphasized
as
relevant.
discusses
recent
modalities
bioprinting,
including
inkjet,
extrusion-based,
laser-assisted
stereolithography,
their
adequacy
tissue
engineering.
The
integrated
use
advanced
techniques
combined
optimized
bioinks
is
highly
promising
approach
fabrication
functional
tissues
restored
vision
treatment
ocular
disorders.
Язык: Английский