TPMS_Scaffold_Generator: A Scaffold-Structure Generator Based on Triply Periodic Minimal Surfaces DOI Creative Commons

Lin Di,

Cong Zhang, Xiyong Chen

и другие.

Deleted Journal, Год журнала: 2024, Номер 3(2), С. 200123 - 200123

Опубликована: Март 22, 2024

With the rapid development of additive manufacturing (AM), scaffold architectures based on triply periodic minimal surfaces (TPMS) have attracted increasing interest in various engineering fields. Nevertheless, they are limited because complexity design process when adopted different research and In this work, we present a free easy-to-use software package called TPMS_Scaffold_Generator, which is coded using MATLAB (Mathworks, Inc., USA). It offers three function tabs homogeneous tab, heterogeneous tab multisymmetrical respectively. Variables include including volume fraction, topology type, unit cell size, length architecture X, Y, Z direction, accuracy, style gradient so forth. TPMS_Scaffold_Generator can generate TPMS scaffolds, especially ultralight scaffolds. The latest version freely available at: https://github.com/LeveeLin/TPMS_Scaffold_Generator.git.

Язык: Английский

Development of lattice structure with selective laser melting process: A state of the art on properties, future trends and challenges DOI
Mehmet Erdi Korkmaz, Munish Kumar Gupta, Grzegorz Robak

и другие.

Journal of Manufacturing Processes, Год журнала: 2022, Номер 81, С. 1040 - 1063

Опубликована: Авг. 2, 2022

Язык: Английский

Процитировано

120
Gaussian curvature–driven direction of cell fate toward osteogenesis with triply periodic minimal surface scaffolds DOI Creative Commons
Yuhe Yang, Tianpeng Xu,

Ho‐Pan Bei

и другие.

Proceedings of the National Academy of Sciences, Год журнала: 2022, Номер 119(41)

Опубликована: Окт. 3, 2022

Leaf photosynthesis, coral mineralization, and trabecular bone growth depend on triply periodic minimal surfaces (TPMSs) with hyperboloidal structure every surface point varying Gaussian curvatures. However, translation of this into tissue-engineered grafts is challenging. This article reports the design fabrication high-resolution three-dimensional TPMS scaffolds embodying biomimicking topography different curvatures, composed body inherent β-tricalcium phosphate, by stereolithography-based printing sintering. The show high porosity interconnectivity. Notably, compared conventional scaffolds, they can reduce stress concentration, leading to increased mechanical strength. They are also found support attachment, proliferation, osteogenic differentiation, angiogenic paracrine function human mesenchymal stem cells (hMSCs). Through transcriptomic analysis, we theorize that hyperboloid induces cytoskeleton reorganization hMSCs, expressing elongated morphology convex direction strengthening cytoskeletal contraction. clinical therapeutic efficacy assessed rabbit femur defect mouse subcutaneous implantation models demonstrate augment new formation neovascularization. In comparison our successfully guide cell fate toward osteogenesis through cell-level directional curvatures drastic yet quantifiable improvements in regeneration.

Язык: Английский

Процитировано

91
Biomimetic scaffolds using triply periodic minimal surface-based porous structures for biomedical applications DOI Creative Commons
Raffaele Pugliese, Serena Graziosi

SLAS TECHNOLOGY, Год журнала: 2023, Номер 28(3), С. 165 - 182

Опубликована: Апрель 29, 2023

The design of biomimetic porous scaffolds has been gaining attention in the biomedical sector lately. Shells, marine sponges, shark teeth, cancellous bone, sea urchin spine, and armadillo armor structure are examples biological systems that have already studied to drive innovative, porous, multifunctional structures. Among these, triply periodic minimal surfaces (TPMSs) attracted scientists for fabrication scaffolds. interest stems from their outstanding properties, which include mathematical controllable geometry features, highly interconnected architectures, high surface area volume ratio, less stress concentration, tunable mechanical increased permeability. All these distinguishing features enable better cell adhesion, optimal integration surrounding tissue avoiding shieldings, a good permeability fluid media oxygen, possibility vascularization. However, sophisticated TPMS-based structures proven challenging fabricate by conventional methods. emergence additive manufacturing (AM) enhanced freedoms flexibility it guarantees could solve some bottlenecks, thus leading surge designing fabricating such this field. Also, feasibility using AM technologies allows obtaining size programmable TPMS printable various materials, polymers metal alloys. Here, comprehensive overview 3D-printed is provided (DfAM) application perspective. First, strategies, algorithms, related topological optimization introduced according diverse requirements. Based on that, performance control pros cons different processes summarized. Lastly, practical applications field presented clarify advantages potential

Язык: Английский

Процитировано

78
3D printed TPMS structural PLA/GO scaffold: Process parameter optimization, porous structure, mechanical and biological properties DOI
Wang Guo,

Yanjuan Yang,

Chao Liu

и другие.

Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials, Год журнала: 2023, Номер 142, С. 105848 - 105848

Опубликована: Апрель 18, 2023

Язык: Английский

Процитировано

65
Impact behavior of periodic, stochastic, and anisotropic minimal surface-lattice sandwich structures DOI Creative Commons
Chukwugozie Jekwu Ejeh, Imad Barsoum, Rashid K. Abu Al‐Rub

и другие.

International Journal of Mechanical Sciences, Год журнала: 2024, Номер 276, С. 109359 - 109359

Опубликована: Май 4, 2024

Recent advancements in 3D printing technologies have made it possible to fabricate intricate lattice architectures with high precision. These lattices can now be utilized design lightweight sandwich structures that serve multiple functions. To enhance the impact loading performance of these structures, is crucial understand how lattice's topological properties, particularly those minimal surface attributes like periodic or stochastic Primitive and Gyroid triply surfaces (TPMS) spinodal-like cellular materials, associate mechanical properties while keeping skin thickness fixed. Thus, this paper explores low-velocity behavior various sheet/shell-based surface-latticed cores woven composite skins. The elasto-plastic-damage numerical simulations consider core periodicity, randomness, anisotropy relative density constant. Core randomness are designed using Gaussian Random Field (GRF) method for spinodal-based materials TPMS. simulation results showed Primitive-lattice exhibits out-of-plane shearing strength, enabling structure demonstrate highest perforation limit. GRF achieved peak load due its anisotropic properties. However, post-yielding bending sheet limited ability resist perforation, absorb dissipated energy. Interestingly, TPMS topology, inherent densely-distributed microstructure, sensitivity rate, resulting enhanced energy absorption dissipation structure. findings offer valuable insights optimizing multifunctional superior their additive manufacturing.

Язык: Английский

Процитировано

20
Heat transfer enhancement of water-cooled triply periodic minimal surface heat exchangers DOI Creative Commons

Wenguang Li,

Weihong Li, Zhibin Yu

и другие.

Applied Thermal Engineering, Год журнала: 2022, Номер 217, С. 119198 - 119198

Опубликована: Авг. 28, 2022

Whether triply periodic minimal surface (TPMS) heat exchangers are applicable to cooling or cold storage systems as a cooler for supercritical carbon dioxide (SCO2) is undocumented. Here the conjugated transfer of SCO2 in TPMS Schoen-G exchanger and printed circuit (PCHE) was predicted based on three-dimensional steady turbulent Reynolds-averaged Navier-Stokes equations, energy equation shear stress transport model using computational fluid dynamics software ANSYS CFX when inlet temperature pressure vary 65–30 ℃ (8–9)MPa. two cooled under counter-flow conditions by stream water with given mass flow rate. It shown that mean coefficient larger than PCHE. As rises, friction factor increases Nusselt number decreases due decreased Reynolds Prandtl number, respectively. The ratio, ratio performance evaluation criterion range 0.38–0.50, 1.07–1.49, 1.45–2.04 PCHE serves reference exchanger. streamlines quite smooth even though areas higher velocity appear. exhibit spiral pattern result extra hydraulic loss. enhancement much better Schwarz-D at 16,000. attributed area more topological tortuosity without separation

Язык: Английский

Процитировано

69
Architected Materials for Additive Manufacturing: A Comprehensive Review DOI Open Access
Nikolaos Kladovasilakis, Konstantinos Tsongas, D. Karalekas

и другие.

Materials, Год журнала: 2022, Номер 15(17), С. 5919 - 5919

Опубликована: Авг. 26, 2022

One of the main advantages Additive Manufacturing (AM) is ability to produce topologically optimized parts with high geometric complexity. In this context, a plethora architected materials was investigated and utilized in order optimize 3D design existing parts, reducing their mass, topology-controlling mechanical response, adding remarkable physical properties, such as porosity surface area volume ratio. Thus, current re-view has been focused on providing definition explaining properties. Furthermore, an up-to-date classification cellular presented containing all types lattice structures. addition, research summarized developed methods that enhance performance materials. Then, effective behavior compared through literature. Moreover, commercial applications potential uses are various industries, aeronautical, automotive, biomechanical, etc. The objectives comprehensive review provide detailed map behavior, explore innovative techniques for improving them highlight topology optimization industrial utilizing additive manufacturing novel

Язык: Английский

Процитировано

64
3D printing of piezoelectric and bioactive barium titanate-bioactive glass scaffolds for bone tissue engineering DOI Creative Commons
Christian Polley, Thomas Distler,

Caroline Scheufler

и другие.

Materials Today Bio, Год журнала: 2023, Номер 21, С. 100719 - 100719

Опубликована: Июль 6, 2023

Bone healing is a complex process orchestrated by various factors, such as mechanical, chemical and electrical cues. Creating synthetic biomaterials that combine several of these factors leading to tailored controlled tissue regeneration, the goal scientists worldwide. Among those piezoelectricity which creates physiological microenvironment plays an important role in stimulating bone cells fostering regeneration. However, only limited number studies have addressed potential combining piezoelectric with state-of-the-art fabrication methods fabricate scaffolds for engineering. Here, we present approach takes advantage modern additive manufacturing techniques create macroporous biomaterial based on bioactive ceramic-crystallised glass composite. Using binder jetting, made barium titanate 45S5 are fabricated extensively characterised respect their physical functional properties. The 3D-printed composite show both suitable mechanical strength behaviour, represented accumulation bone-like calcium phosphate surface. Piezoelectric mimic or even surpass constants ranging from 1 21 pC/N achieved, depending composition MC3T3-E1 osteoblast precursor cells, high cytocompatibility coupled cell attachment proliferation, rendering titanate/45S5 composites promising candidates

Язык: Английский

Процитировано

36
Recent Advancements in Design Optimization of Lattice‐Structured Materials DOI Creative Commons
Abdulla Almesmari, Ali N. Alagha, Mohammed M. Naji

и другие.

Advanced Engineering Materials, Год журнала: 2023, Номер 25(17)

Опубликована: Июнь 16, 2023

Metamaterials, also known as lattice‐structured materials, imitate the multifunctionality of natural architects tailoring their physical properties is associated with manipulating microstructure. As recent evolution additive manufacturing enables creation intricate geometries minimal material wastage, improving design to cycle lattice structured materials has become one trending research areas. Triply periodic surface (TPMS) and plate are renowned for exceptional mechanical behavior in lightweight applications. Apparently, several types optimization strategies explored maximize performance better biocompatibility loading resistance. Some these include functional gradation multimorphology hybridization that comprehensively described this review. Their benefits drawbacks highlighted a focus on TPMS materials. The review anticipates utilization automated exploration methods (i.e., topology data‐driven methods) further enhance procedure

Язык: Английский

Процитировано

33
Triply Periodic Minimal Surface-Based Scaffolds for Bone Tissue Engineering: A Mechanical, In Vitro and In Vivo Study DOI Creative Commons
Ekaterina Maevskaia, Julien Guerrero, Chafik Ghayor

и другие.

Tissue Engineering Part A, Год журнала: 2023, Номер 29(19-20), С. 507 - 517

Опубликована: Май 22, 2023

Triply periodic minimal surfaces (TPMSs) are found to be promising microarchitectures for bone substitutes owing their low weight and superior mechanical characteristics. However, existing studies on application incomplete because they focus solely biomechanical or in vitro aspects. Hardly any vivo where different TPMS compared have been reported. Therefore, we produced hydroxyapatite-based scaffolds with three types of microarchitectures, namely Diamond, Gyroid, Primitive, them an established Lattice microarchitecture by testing, 3D-cell culture, implantation. Common all four was the constriction a sphere 0.8 mm diameter, which earlier microarchitectures. Scanning μCT revealed precision reproducibility our printing method. The analysis showed significantly higher compression strength Gyroid Diamond samples Primitive Lattice. After culture human marrow stromal cells control osteogenic medium, no differences between these were observed. from Diamond- Gyroid-based highest ingrowth bone-to-implant contact vivo. designs appear most TPMS-type tissue engineering regenerative medicine. Extensive defects require grafts. To match requirements, based triply surface (TPMS)–based could used as substitutes. This work is dedicated investigation osteoconductive properties TPMS-based determine influencing factors behavior choose design engineering.

Язык: Английский

Процитировано

27