Effects of long-term continuous cultivation on the structure and function of soil bacterial and fungal communities of Fritillaria Cirrhosa on the Qinghai-Tibetan Plateau DOI Creative Commons

Dan Gao,

Xusheng Gao,

Ye Wang

и другие.

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Сен. 12, 2024

Язык: Английский

Study on Quality Germplasm Screening and Drought Resistance of <i>Trollius chinensis</i> Bunge in Hulunbuir DOI

慧 智

Botanical Research, Год журнала: 2025, Номер 14(01), С. 58 - 67

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Integrating metabolomics, network pharmacology and pharmacological verification analysis provides new insights into the anti-inflammatory and anti-tussive properties of Fritillaria cirrhosa bulbs DOI Creative Commons

Can Zhao,

Jianyun Zhang,

Zhihuang Zhao

и другие.

Journal of Ethnopharmacology, Год журнала: 2025, Номер unknown, С. 119460 - 119460

Опубликована: Фев. 1, 2025

Fritillaria cirrhosa bulbs, referred to as Chuanbeimu in traditional Chinese medicine (TCM), are extensively used for recognized anti-inflammatory and anti-tussive effects. Both Songbei (SB) Qingbei (QB), which from this plant, have been separately medicine. However, the differences similarities their bioactive components effects remain unclear. We aimed analyse metabolic profiles of F. bulbs across different growth years explore properties two distinct medicinal materials. With nontargeted technology, main were detected. Principal component analysis (PCA) pathway enrichment carried out determine differentially expressed metabolites between years. Network pharmacology was subsequently relationships among components, diseases, key targets, pathways by constructing a network model. The drug-containing serum on cellular inflammatory factors analysed through vitro assays. A total 1349 compounds identified bulb samples. PCA revealed SB (1- 2-year-old) QB (3-, 4-, 5-year-old). Notably, 4-methoxycinnamaldehyde, tenuifoliside A, LysoPC 20:4, morpholine-4-carboximidamide hydrobromide potential distinguishing QB. more common targets related (PPARG, PPARA, PTGS1, XDH) OPRM1, DRD2, SLC6A4, HTR2A) than KEGG that inflammation cough, including tryptophan metabolism arachidonic acid metabolism, enriched group. Cellular assays effects, with having greater IL-6 TNF-α IL-1β overall By integrating metabolomic analyses, classification into based characteristics observed justified certain extent. This study provides new insights, guiding clinical use these treatments cough.

Язык: Английский

Процитировано

0
Manipulation of artificial light environment improves tropane alkaloids content in Atropa belladonna L. DOI

Xupeng Gu,

Linlin Yang, Di Zhang

и другие.

Plant Physiology and Biochemistry, Год журнала: 2025, Номер unknown, С. 109828 - 109828

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Light quality modulates yields and secondary metabolite accumulation in Fritillaria cirrhosa: Insights from rhizosphere metabolomics and microbiomics DOI Creative Commons
Yi Lu, Dan Gao,

Xusheng Gao

и другие.

Industrial Crops and Products, Год журнала: 2025, Номер 229, С. 120967 - 120967

Опубликована: Апрель 10, 2025

Язык: Английский

Процитировано

0
Effects of long-term continuous cultivation on the structure and function of soil bacterial and fungal communities of Fritillaria Cirrhosa on the Qinghai-Tibetan Plateau DOI Creative Commons

Dan Gao,

Xusheng Gao,

Ye Wang

и другие.

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Сен. 12, 2024

Язык: Английский

Процитировано

3