Journal of Hazardous Materials, Год журнала: 2024, Номер 485, С. 136960 - 136960
Опубликована: Дек. 20, 2024
Язык: Английский
Annals of Global Health, Год журнала: 2024, Номер 90(1)
Опубликована: Янв. 1, 2024
The United Nations has declared that humans have a right to clean air. Despite this, many deaths and disability-adjusted life years are attributed air pollution exposure each year. We face both challenges quality opportunities improve, but several areas need be addressed with urgency.
Язык: Английский
Процитировано
24
Water Research, Год журнала: 2023, Номер 247, С. 120784 - 120784
Опубликована: Окт. 26, 2023
Язык: Английский
Процитировано
21
Environmental Chemistry and Ecotoxicology, Год журнала: 2024, Номер 6, С. 51 - 64
Опубликована: Янв. 1, 2024
Liquid crystal monomers (LCMs) are synthetic organic chemicals widely used in the manufacture of liquid displays (LCDs) digital electronic devices. As human interactions with electronics like computers and cell phones intensify, exposure to LCMs is concern. Nevertheless, there limited research on occurrence biological non-biological matrices. We developed a method determine 60 electronic-waste panels, indoor dust, feces, urine using gas chromatography–mass spectrometry (GC–MS). Solid matrices (i.e., dust feces) were extracted solid-liquid extraction (SLE) whereas urine) solid phase (SPE). Indoor feces extracts purified by passage through silica gel packed gravity columns. The instrument limits detection (LODs) quantification (LOQs) ranges 0.05–13.0 0.18–39.1 ng/mL, respectively. Recoveries all target analytes fortified at concentrations 10 100 ng/mL LCD range 71.1–130%, standard deviations 0.01–33%. Repeated analyses similarly samples yielded intra-day inter-day variations (CV) 0.32–12.6% 0.76–14.3%, Matrix effects, calculated from matrices, ranged −28.5% 28.5%. was applied analysis dog urine, which found contain 22, 42, 46, 18 targeted LCMs, panels (∑LCM = 1780 ± 165 ng/cm2 for desktop computer monitors; 166,900 80,100 smartphone screens), 2030 1260 ng/g), 1990 2000 ng/g dw), 24.0 14.6 ng/mL). can be wide environmental samples.
Язык: Английский
Процитировано
6
Journal of Allergy and Clinical Immunology, Год журнала: 2024, Номер 154(4), С. 835 - 846
Опубликована: Авг. 24, 2024
Because of the disproportionate amount time that people spend indoors and complexities air pollutant exposures found there, indoor pollution is a growing concern for airway health. Both infiltration outdoor into space sources (such as smoke from tobacco products, cooking or heating practices combustion associated fuels, household materials) contribute to unique exposure mixtures. Although there substantial literature on chemistry pollution, research focused health effects only beginning emerge remains an important area need protect public We provide review emerging spanning past 3 years relating health, with specific focus impact either individual common lower airways. Factors defining susceptibility and/or vulnerability are reviewed consideration priority populations modifiable risk factors may be targeted advance equity.
Язык: Английский
Процитировано
6
Journal of Hazardous Materials, Год журнала: 2024, Номер 468, С. 133848 - 133848
Опубликована: Фев. 22, 2024
Язык: Английский
Процитировано
5
The Science of The Total Environment, Год журнала: 2024, Номер 947, С. 174443 - 174443
Опубликована: Июль 2, 2024
Liquid crystal monomers (LCMs) are a class of emerging contaminants concern predicted to be persistent, bioaccumulative and toxic (PBT). Being one the key components in liquid displays (LCDs), disposal LCD containing devices is closely related emission LCMs into environment. have been detected wide range environmental matrices including dust, sediment, soil, sewage leachate, air, with concentration ranges between 17 2121 ng/g found indoor residential dust. Furthermore, they on human skin at concentrations up 2,071,000 ng/m
Язык: Английский
Процитировано
5
The Science of The Total Environment, Год журнала: 2023, Номер 908, С. 168328 - 168328
Опубликована: Ноя. 4, 2023
Язык: Английский
Процитировано
11
Environmental Science & Technology, Год журнала: 2025, Номер unknown
Опубликована: Апрель 6, 2025
Liquid crystal monomers (LCMs) have emerged as a new class of contaminants, yet their health risks remain unclear due to limited toxicity data. This study assessed 46 structurally diverse LCMs using primary mouse hepatocytes, revealing significant cytotoxicity in 22 compounds, particularly 3OCB, tFMeO-3cHtFT, 2OdF3B, 2O2cHdFB, and 2CB. To predict across thousands reported LCMs, classification models quantitative structure-activity relationship (QSAR) were developed. For five optimal models, sensitivity, specificity, prediction accuracy for the respective training validation sets >0.900. In terms prediction, we established k-nearest neighbor-based QSAR model, its coefficient determination (R2), leave-one-out cross-validation Q2 (Q2LOO), externally explained variance (Q2EXT), concordance correlation (CCC) all greater than 0.850. These integrated into CytoToxLCM software, enabling high-throughput screening 1127 LCMs. The results virtual showed that over 40% predicted be cytotoxic, with fluorinated ranking most toxic. this are reliable predicting or untested aiding better understanding potential hepatotoxic effects contributing design safer industrial application alternatives.
Язык: Английский
Процитировано
0
Life Sciences, Год журнала: 2025, Номер 372, С. 123632 - 123632
Опубликована: Апрель 10, 2025
Язык: Английский
Процитировано
0
Critical Reviews in Environmental Science and Technology, Год журнала: 2024, Номер 54(24), С. 1902 - 1919
Опубликована: Июль 11, 2024
Язык: Английский
Процитировано
2