Oceans,
Год журнала:
2024,
Номер
5(2), С. 181 - 195
Опубликована: Апрель 3, 2024
Tetrabromobisphenol
A
(TBBPA)
is
a
fire-retardant
containing
bromine,
produced
in
large
quantities
worldwide
and
extensively
used
several
industrial
products.
This
compound
was
identified
as
potential
contaminant
of
the
environment,
causing
toxicity
to
organisms.
However,
its
remains
poorly
understood
marine
bivalves.
The
first
objective
this
work
evaluate
impact
TBBPA
on
mussels
(Mytilus
galloprovincialis)
exposed
for
28
days
various
concentrations
(0,
1,
10,
100
µg·L−1),
by
assessing
stress
biomarkers’
responses
(Glutathione
S-transferase,
superoxide
dismutase,
catalase,
lipid
peroxidation,
total
antioxidant
capacity,
ubiquitin,
caspase-3
acetylcholinesterase).
results
showed
that
lower
(1
10
µg·L−1)
were
efficiently
detoxified,
suggested
GST
activities,
which
supported
other
biomarkers.
most
pronounced
effects
observed
animals
highest
concentration
(100
suggesting
oxidative
stress.
Additionally,
significant
strong
correlations
found
between
capacity
some
biomarkers
(superoxide
dismutase
peroxidation),
showing
processes
involved
fighting
are
working
avoid
cell
injury.
In
brief,
mussels’
defense
mechanisms
capable
dealing
with
exposure
tested.
Despite
this,
risk
consuming
shellfish
or
fishery
products
contaminated
should
be
cause
concern.
The Science of The Total Environment,
Год журнала:
2023,
Номер
872, С. 162108 - 162108
Опубликована: Фев. 10, 2023
Marine
organisms
are
constantly
exposed
to
multiple
stressors
including
pollutants
released
into
the
environment,
such
as
personal
care
products
(PCPs),
and
climate
change-derived
factors,
namely
warming,
which
aggravated
by
anthropogenic
drivers
pose
increasing
pressure
on
coastal
ecosystems.
Avobenzone
(AVO)
is
one
of
most
used
ultraviolet
(UV)
filters
in
PCPs
have
been
increasingly
and,
thereby,
identified
aquatic
environments.
However,
data
regarding
influence
warming
impacts
caused
AVO
bivalves
lacking.
Mussels
considered
good
bioindicators
thus
being
often
employed
ecotoxicology
studies.
Hence,
present
study
aimed
evaluate
toxic
effects
an
environmentally
relevant
concentration
(0.5
μg/L)
(21
°C),
acting
alone
or
combination,
sperm
adults
Mediterranean
mussel
species
Mytilus
galloprovincialis,
through
vitro
vivo
tests,
respectively.
were
evaluated
assessing
oxidative
status,
viability,
genotoxicity,
motility,
kinetics
sperm,
together
with
quantification
energy
content,
metabolic
capacity,
biological
defence
mechanisms,
cellular
damage,
neurotoxicity
adults.
induced
genotoxicity
increased
respiration
rate
while
enhancing
biotransformation
enzymes'
activity
Exposure
led
increase
rate,
ROS
overproduction,
viability
decrease
whereas
capacity
combined
stress,
decreased
motility
only
antioxidant
was
enhanced
Overall,
demonstrated
that
when
combination
both
more
prominent.
Furthermore,
considering
multiple-stressor
scenario
tested,
major
occurred
male
gametes
comparison
Journal of Separation Science,
Год журнала:
2025,
Номер
48(2)
Опубликована: Фев. 1, 2025
ABSTRACT
The
rise
of
plastic
pollution
in
marine
environments
has
been
heavily
documented,
with
particular
focus
on
the
physical
impacts
plastics
can
have
biota.
But,
also
sorb
a
range
hydrophobic
chemical
pollutants,
acting
as
vectors
for
transportation
these
compounds
throughout
environments.
Therefore,
an
analytical
method
that
target
both
biota
and
matrices
will
be
key
to
advance
our
understanding
link
between
chemicals
environment,
pollution,
effects
Here,
efficient
detection
quantification
broad
suite
samples
was
developed.
Five
extraction
methods
were
trialed
analysis
21
pesticides,
PFAS,
pharmaceuticals
plastics.
This
included
three
ultrasonic
two
QuEChERS
methods.
Ultrasonic
acetonitrile
microcentrifuge
step
then
concentration
by
Bond
Elut
Carbon
SPE
resulted
best
recovery
across
most
compounds.
Of
trialed,
16
efficiently
quantified.
Method
limits
0.02
4.81
ppb
(mLODs)
0.06
14.60
(mLOQs).
is
widely
applicable
supports
routine
evaluations
environmental
safety
monitoring
protocols.
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(4), С. 1753 - 1753
Опубликована: Фев. 19, 2025
Polybrominated
biphenyls
(PBBs)
are
commonly
used
flame
retardants
that
pose
severe
risks
to
humans.
However,
there
is
a
lack
of
systematic
research
on
the
transformation
process
and
biological
toxicities
PBBs
in
environment,
which
not
conducive
prevention
control
pollution
PBBs.
Therefore,
pathways
(i.e.,
photodegradation,
microbial
degradation,
combustion
oxidation,
vivo
metabolism)
previously
designed
PBB
substitutes
were
deduced
first.
Then
potential
rodent
carcinogenicity,
toxicity,
mutagenicity,
developmental
skin
eye
irritation,
sensitization,
aquatic
toxicity
products
evaluated
using
toxicokinetics
(TOPKAT)
model.
Finally,
3D
quantitative
structure
activity
relationship
(3D-QSAR)
models
constructed
assess
human
hepatotoxicity,
epigenetic
neurotoxicity,
immunotoxicity)
PBBs,
substitutes,
their
products.
Results
showed
exhibit
high
toxicity)
organisms.
The
D3-A1
molecule
had
highest
carcinogenic
risk
probability
at
0.826.
dihydroxy
metabolite
2,2'-OH-PBB-80
PBB-80
presented
(toxicity
0.713).
dibenzofuran
(PBDF)
strongest
irritation
(probability
0.995).
oxidation
exhibited
higher
ecological
health
than
other
Among
humans,
was
theoretically
significant,
with
characterization
values
ranging
from
70.53
100.87.
This
first
study
comprehensively
evaluate
by
combining
inference
prediction
product
toxicities,
providing
theoretical
support
for
design
environmentally
friendly
future
studies.
Chemosensors,
Год журнала:
2025,
Номер
13(3), С. 88 - 88
Опубликована: Март 4, 2025
Deep
eutectic
solvents
(DESs),
a
novel
class
of
eco-friendly
solvents,
are
attracting
considerable
attention
in
extraction
techniques.
In
this
study,
hydrophobic
DES,
created
by
combining
quaternary
ammonium
salt
and
hexanoic
acid,
was
coated
onto
commercial
cellulose
membrane
for
polycyclic
musks
(cashmeran,
celestolide,
galaxolide,
tonalid)
microextraction
from
surface
waters
followed
gas-chromatography–mass
spectrometry
(GC
MS)
analysis.
A
series
DESs
were
synthesized
characterized
to
identify
suitable
candidates
use
as
coating
on
membranes.
factorial
design
approach
employed
investigate
key
factors,
including
DES
volume,
type,
dissolving
solvent
incorporation
time,
duration,
following
preliminary
selection
the
membrane,
solvent.
Under
optimized
conditions,
acetate
impregnated
with
(TBAB:C6,
1:3
molar
ratio)
used
1
h
extract
water;
then
dissolved
methanol
prior
GC-MS
The
DES-coated
demonstrated
linear
detection
range
2.5
100
μg/L,
limits
(LODs)
ranging
0.06
0.15
µg/L,
while
LOQ
values
varied
0.2
0.5
µg/L.
validated
method
successfully
applied
real
samples,
allowing
us
find
presence
galaxolide
tonalide.
The Science of The Total Environment,
Год журнала:
2023,
Номер
912, С. 168664 - 168664
Опубликована: Ноя. 21, 2023
In
this
study
we
found
that
endocrine
disrupting
chemicals
(EDCs)
were
omnipresent
in
a
tropical
seabird
community
comprising
diverse
ecological
guilds
and
distinct
foraging
trophic
preferences.
Because
EDCs
tend
to
bioaccumulate
within
the
food
web
microplastics
can
absorb
release
harmful
chemical
compounds,
our
findings
draw
attention
potential
threats
wildlife.
Thus,
goal
of
was
investigate
role
plastic
ingestion,
patterns
(δ
