Advances in computer and electrical engineering book series,
Год журнала:
2024,
Номер
unknown, С. 372 - 381
Опубликована: Март 15, 2024
This
study
presents
a
comprehensive
failure
rate
examination
for
implantable
antennas,
employing
liability
tree-based
analysis
focused
on
clamped
double
subsystem
(CDSM)
equipped
with
DC
short
voltage
protective
functionality.
The
enhanced
feature
of
the
CDSM
aims
to
improve
security
and
safety
antennas
used
in
critical
applications.
However,
this
subsystem's
design
necessitates
use
additional
IGBTs,
diodes,
capacitors
compared
standard
configurations,
consequently
increasing
complexity
potential
rate.
Given
that
demanding
converter
operation
can
escalate
rate,
conducting
precise
reliability
becomes
vital
deployment
these
devices.
A
durability
is
undertaken
address
operational
characteristics
antennas.
Fault
Tree
Analysis
(FTA)
utilized
evaluate
risk
greater
precision
than
previous
methods,
which
mainly
considered
component
types,
quantities,
network
connectivity
states.
International Journal of Nanomedicine,
Год журнала:
2023,
Номер
Volume 18, С. 3973 - 3988
Опубликована: Июль 1, 2023
Abstract:
Pancreatic
cancer
is
a
highly
malignant
and
incurable
disease,
characterized
by
its
aggressive
nature
high
fatality
rate.
The
most
common
type
pancreatic
ductal
adenocarcinoma
(PDAC),
which
has
poor
prognosis
mortality
Current
treatments
for
mainly
encompass
surgery,
chemotherapy,
radiotherapy,
targeted
therapy,
combination
regimens.
However,
despite
efforts
to
improve
prognosis,
the
5-year
survival
rate
remains
very
low.
Therefore,
it's
urgent
explore
novel
therapeutic
approaches.
With
rapid
development
of
strategies
in
recent
years,
new
ideas
have
been
provided
treating
cancer.
This
review
expositions
advancements
nano
drug
delivery
system,
molecular
drugs,
photo-thermal
treatment
combined
with
nanotechnology
It
comprehensively
analyzes
prospects
cancer,
aiming
at
deeper
understanding
existing
drugs
approaches,
promoting
attempting
enhance
effect
patients
this
disease.
Keywords:
Environmental Research,
Год журнала:
2023,
Номер
238, С. 116909 - 116909
Опубликована: Сен. 4, 2023
Xenobiotic
pollution
in
environment
is
a
potential
risk
to
marine
life,
and
human
health.
Nanobiotechnology
an
advanced
emerging
solution
for
the
removal
of
environmental
pollutants.
Adsorption-based
technologies
are
being
used
alleviate
global
prevalence
xenobiotics
like
dyes,
due
their
high
efficacy
cost
effectiveness.
Current
study
explored
nanobiochar
syntehsized
via
ultrasonication
centrifugation
from
rice
husk
dye
water.
It
involves
synthesis
biochar
Safranin,
Malachite
green,
mixture
both
aqueous
Biochar
was
synthesized
through
pyrolysis
at
600
°C
2
h.
To
convert
it
into
nanobiochar,
sonication
techniques
were
applied.
The
yield
obtained
27.5%
0.9%
nanobiochar.
Nanobiochar
analysis
Fourier-Transform
Spectrometer
(FTIR),
X-ray
Power
Diffraction
(XRD)
scanning
electron
microscopy
(SEM)
suggested
its
crystalline
nature
having
minerals
rich
silicon,
with
cracked
disintegrated
carbon
structure
temperature
processing
treatments.
Removal
dyes
by
evaluated
changing
different
physical
parameters
i.e.,
dose,
pH,
temperature.
Pseudo-first
order
model
pseudo-second
applied
studying
adsorption
kinetics
mechanism.
Kinetics
followed
suggesting
process
chemical
sorption.
High
found
higher
concentration
temperature,
neutral
pH.
Maximum
elimination
percentages
safranin,
malachite
as
91.7%,
87.5%,
85%
respectively.
We
conclude
that
could
be
media.
CNS Neuroscience & Therapeutics,
Год журнала:
2024,
Номер
30(5)
Опубликована: Май 1, 2024
Abstract
Gliomas
are
the
most
common
primary
tumors
of
central
nervous
system,
with
glioblastoma
multiforme
(GBM)
having
highest
incidence,
and
their
therapeutic
efficacy
depends
primarily
on
extent
surgical
resection
postoperative
chemotherapy.
The
role
intracranial
blood–brain
barrier
occurrence
drug‐resistant
gene
O6‐methylguanine‐DNA
methyltransferase
have
greatly
limited
chemotherapeutic
agents
in
patients
GBM
made
it
difficult
to
achieve
expected
clinical
response.
In
recent
years,
rapid
development
nanotechnology
has
brought
new
hope
for
treatment
tumors.
Nanoparticles
(NPs)
shown
great
potential
tumor
therapy
due
unique
properties
such
as
light,
heat,
electromagnetic
effects,
passive
targeting.
Furthermore,
NPs
can
effectively
load
drugs,
significantly
reduce
side
effects
improve
efficacy,
showing
chemotherapy
glioma.
this
article,
we
reviewed
mechanisms
glioma
drug
resistance,
physicochemical
NPs,
advances
resistance.
We
aimed
provide
perspectives
Heliyon,
Год журнала:
2023,
Номер
9(9), С. e19659 - e19659
Опубликована: Авг. 31, 2023
In
this
research,
zinc
oxide
(ZnO)
nanoparticles
doped
with
different
percentages
of
produced
cobalt
using
the
green
synthesis
method.
ZnO
showed
good
cellular
and
microbial
toxicity
due
to
their
high
surface-to-volume
ratio.
Adding
metal
nanostructure
can
lead
appearance
a
new
feature.
To
investigate
effect
adding
metal,
synthesized
containing
3
6%
were
plant
extract.
The
resulting
nanostructures
characterized
by
Raman
spectroscopy,
UV–Visible
spectrometer,
X-ray
diffraction,
Field
emission
scanning
electron
microscopy.
Ultimately,
samples'
cytotoxicity
antimicrobial
tests
performed.
XRD
confirmed
formation
hexagonal
wurtzite
structure.
imaging
that
doping
resulted
in
decrease
average
crystal
size.
results
doping,
particle
size
decreased
slightly.
effects
all
three
studies,
leads
an
increase
compared
non-doped
nanoparticles.
Translational Oncology,
Год журнала:
2024,
Номер
45, С. 101975 - 101975
Опубликована: Апрель 30, 2024
Hepatocellular
carcinoma
(HCC)
is
the
most
prevalent
type
of
liver
cancer,
mainly
occurring
in
Asian
countries
with
an
increased
incidence
rate
globally.
Currently,
several
kinds
therapies
have
been
deployed
for
HCC
therapy
including
surgical
resection,
chemotherapy,
radiotherapy
and
immunotherapy.
However,
this
tumor
still
incurable,
requiring
novel
strategies
its
treatment.
The
nanomedicine
has
provided
new
insights
regarding
treatment
cancer
that
liposomes
as
lipid-based
nanoparticles,
widely
applied
due
to
their
biocompaitiblity,
high
drug
loading
ease
synthesis
modification.
current
review
evaluates
application
therapy.
drugs
genes
lack
targeting
ability
into
tissues
cells.
Therefore,
or
on
can
increase
accumulation
site
suppression.
Moreover,
stimuli-responsive
pH-,
redox-
light-sensitive
are
able
deliver
microenvironment
improve
therapeutic
index.
Since
a
number
receptors
upregulate
cells,
functionalization
lactoferrin
peptides
promote
towards
phototherapy
be
induced
by
through
phtoosensitizers
stimulate
photothermal-
photodynamic-driven
ablation
Overall,
findings
line
fact
promising
nanocarriers
HCC.
Polymers for Advanced Technologies,
Год журнала:
2024,
Номер
35(12)
Опубликована: Дек. 1, 2024
ABSTRACT
This
review
aims
to
provide
a
comprehensive
analysis
of
recent
advancements
in
smart
microneedles
(MNs)
within
the
biomedical
field,
focusing
on
integration
stimuli‐responsive
polymers
for
enhanced
therapeutic
and
diagnostic
applications.
Conventional
drug
delivery
methods
are
known
face
limitations
precision,
safety,
patient
compliance,
which
can
be
addressed
by
innovative
features
MNs.
Through
use
various
polymers,
these
MNs
have
been
designed
react
environmental
or
physiological
cues,
allowing
on‐demand
release,
biomarker
sensing,
localized
interventions.
Fundamental
materials
used
fabrication
MNs,
including
metals,
composite
hydrogels,
reviewed,
different
categories
stimuli‐responsiveness,
such
as
photo,
electro,
thermal,
mechanical,
biochemical,
explored.
Application‐specific
designs
areas
delivery,
cancer
therapy,
diabetes
management,
skin
disease
treatments
also
examined.
this
discussion,
it
is
highlighted
that
poised
play
significant
role
advancing
personalized
noninvasive
medical
treatments.
