The Science of The Total Environment,
Год журнала:
2024,
Номер
946, С. 173809 - 173809
Опубликована: Июнь 5, 2024
Drugs
are
chemical
compounds
used
to
treat
and
improve
organic
dysfunctions
caused
by
diseases.
These
include
analgesics,
antibiotics,
antidepressants,
antineoplastics.
They
can
enter
aquatic
environments
through
wastewater
streams,
where
their
physico-chemical
properties
allow
metabolites
distribute
accumulate.
Current
climate
change
associated
extreme
weather
events
may
significantly
impact
these
substances'
toxicity
organisms'
sensitivity.
Among
the
chemicals
present
in
is
non-steroidal
anti-inflammatory
drug
diclofenac
(DIC),
which
EU
monitors
due
its
concentration
levels.
This
study
investigated
influence
of
temperature
(control
at
17
°C
vs.
21
°C)
on
effects
DIC
(0
μg/L
1
μg/L)
mussel
species
Mytilus
galloprovincialis.
Significant
results
were
observed
between
°C.
Organisms
exposed
higher
showed
a
decrease
several
parameters,
including
metabolic
capacity
detoxification,
particularly
with
prolonged
exposure.
However,
some
after
days,
M.
galloprovincialis
no
differences
from
control,
indicating
adaptation
stress.
The
this
confirm
that
concentrations
environment,
when
combined
increased
temperatures,
produce
oxidative
stress
adversely
affect
biochemical
physiological
performance.
also
validates
as
bioindicator
for
assessing
environmental
contamination
DIC.
Beyond
direct
organisms,
presence
pharmaceuticals
like
environment
highlights
interconnectedness
human,
animal,
ecosystem
health,
underscoring
One
Health
approach
understanding
mitigating
pollution.
Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology,
Год журнала:
2023,
Номер
270, С. 109645 - 109645
Опубликована: Май 5, 2023
Plastics,
long-chain
artificial
polymers,
are
used
worldwide
with
a
global
production
of
350
million
tonnes
per
year.
Various
degradation
processes
transform
plastics
into
smaller
fragments
divided
micro,
meso
and
macroplastics.
In
various
industries,
such
as
construction,
certain
plastic
additives
to
improve
flexibility
enhance
performance.
Plastic
include
phthalates
(PAE),
dibutyl
phthalate
(DPB)
diethyl
(DEP).
Due
the
use
additives,
these
small
different
shapes
colours
present
in
all
environmental
compartments.
For
their
characteristics,
PAEs
can
be
introduced
particularly
by
ingestion,
inhalation
dermal
absorption.
They
accumulate
human
body,
where
they
have
already
been
identified
blood,
amniotic
fluid
urine.
The
purpose
this
review
is
gather
effects
that
on
systems
body.
Being
endocrine
disruptors,
erythrocytes
how
considered
targets
for
xenobiotics
analysed.
influence
reproductive
system
was
also
examined.
Phthalates
therefore
often
overused.
properties,
reach
tissues
negative
impact
health.
aim
give
an
overview
presence
hazards.
Therefore,
should
reduced,
replaced
disposal
improved.
The Science of The Total Environment,
Год журнала:
2023,
Номер
890, С. 164075 - 164075
Опубликована: Май 23, 2023
Caffeine
(Caff)
is
one
of
the
most
widely
used
substances
in
human
diet
and
a
well-recognized
drug.
Its
input
into
surface
waters
remarkable,
but
biological
effects
on
aquatic
organisms
are
unclear,
particularly
combination
with
pollutants
suspected
modulatory
activity,
like
microplastics
(MP).
The
aim
this
study
was
to
reveal
impact
marine
mussel
Mytilus
galloprovincialis
(Lamark,
1819)
Caff
(20.0
μg
L-1)
environmentally
relevant
(Mix)
MP
1
mg
L-1
(size
35-50
μm)
after
exposure
for
14
days.
Untreated
exposed
separately
groups
were
also
examined.
Cell
viability
cell
volume
regulation
hemocytes
digestive
cells,
as
well
indexes
oxidative
stress,
glutathione
(GSH/GSSG)
metallothioneins
levels,
caspase-3
activity
gland
assessed.
Mix
reduced
Mn-superoxide
dismutase,
catalase,
S-transferase
activities
level
lipid
peroxidation,
increased
viability,
GSH/GSSG
ratio
(by
1.4-1.5-fold),
their
Zn
content,
while
did
not
affect
stress
metallothionein-related
chelation.
Protein
carbonyls
targeted
all
exposures.
distinguishing
feature
group
decline
(2-fold)
low
viability.
multi-stress
effect
shown
by
worsening
cells
confirmed
discriminant
analysis
biochemical
indexes.
special
capabilities
M.
sentinel
organism
make
it
an
excellent
bio-indicator
reflecting
sub-chronic
exposures
potentially
harmful
substances.
identification
modulation
individual
combined
increases
need
base
monitoring
programs
studies
Ecological Indicators,
Год журнала:
2023,
Номер
150, С. 110200 - 110200
Опубликована: Апрель 3, 2023
Microplastic
pollution
has
become
pervasive.
Identifying
a
bioindicator
species
to
track
the
occurrence
and
effects
of
microplastics
(MPs)
on
ecosystems
is
crucial
for
determining
their
impact
environment.
The
digestive
tract
Procambarus
clarkii
was
thought
be
interest
investigating
MPs
accumulation
in
freshwater
organisms.
Our
hypothesis
that
same
type
found
abiotic
compartments
(water
sediment)
could
P.
clarkii,
which
would
make
it
an
ideal
candidate
use
as
MP
ecosystems.
Water,
sediment,
specimens
were
collected
from
four
sites
lentic
ecosystem
(Lake
Candia;
northwestern
Italy)
two
consecutive
years
(2021–2022).
mean
abundance
1.75
±
0.95
items/m3
2021
2
0.81
2022
water
samples
6.75
1.5
items/kg
8
sediment
2022,
respectively.
In
2021,
average
0.06
0.07
items/g
males
0.05
females;
0.04
females,
fibers
fragments
(black,
white,
blue,
light
blue)
polypropylene
polyethylene
terephthalate
biotic
compartments.
generalized
linear
mixed
model
revealed
number
predicted
only
by
total
weight:
lowest
recorded
crayfish
with
highest
weight
probably
due
feeding
habits
clarkii.
findings
suggest
invasive
(smaller
individuals,
particular)
good
since
items
Further
research
needed
better
understand
behavior
dynamics
aquatic
Ecological Indicators,
Год журнала:
2023,
Номер
155, С. 111058 - 111058
Опубликована: Окт. 7, 2023
Microplastics
(MPs),
which
are
small
plastic
particles
measuring
less
than
5
mm
in
size,
have
emerged
as
a
significant
environmental
concern
marine
ecosystems
worldwide.
The
presence
of
MPs
aquatic
environments
has
increased
due
to
the
contributions
from
anthropogenic
and
terrestrial
sources,
raising
concerns
about
their
abundance
organisms.
primarily
originate
photo-degradation
larger
debris
(macroplastics),
with
release
into
environment
often
occurring
through
breakdown
additive
compounds.
ingestion
poses
eco-toxicological
risks
organisms,
causing
damage
gastrointestinal
(GI)
tracts
stomachs
affected
Approximately
80
%
can
be
classified
either
primary
such
those
generated
during
production
skincare
products,
tires,
use
carriers
for
pharmaceutical
or
secondary
sources
resulting
improper
disposal
plastics
near
coastal
areas
water
bodies.
issue
potential
effects
on
ecosystem
demands
attention.
In
conclusion,
this
review
provides
comprehensive
overview
vulnerability
microplastics
environments,
consolidating
current
understanding
distribution,
fate,
ecological
impacts.
It
emphasizes
urgent
need
ongoing
research
proactive
measures
mitigate
long-term
consequences
microplastic
pollution
essential
services
they
provide.
Chemosphere,
Год журнала:
2023,
Номер
336, С. 139273 - 139273
Опубликована: Июнь 19, 2023
Due
to
their
uncontrolled
use,
plastics
has
become
an
environmental
concern,
not
only
for
varying
dimension
but
also
the
potential
release
of
substances
such
as
phthalates
(PAEs)
and
non-phthalates
(NPPs)
into
water.
Phthalates
are
most
common
plasticizers
non-phthalate
di
(2-ethylhexyl)
terephthalate
(DEHT)
have
been
lately
found
in
marine
environment.
Mytilus
galloprovincialis
is
a
well-known
bioindicator
aquatic
environments
due
its
ability
accumulate
wide
variety
xenobiotics,
including
plasticizers.
Hence,
aim
this
study
was
evaluate
bioaccumulation
effects
NPP
DEHT
on
M.
galloprovincialis.
To
purpose,
following
exposure
at
1
mg/l
(DEHT1)
100
(DEHT100),
accumulation
tissues
total
lipids
fatty
acid
(FA)
composition,
protein
content,
cell
viability,
recover
volume
changes
biomarkers
oxidative
stress
were
assessed.
Mussels
able
bioaccumulate
tissues,
with
statistically
significant
increase
compared
control
organisms.
Differences
FA
composition
observed
after
exposure,
since
C16:0,
C18:0,
C20:5ω-3
C22:6ω-3
significantly
decreased
from
exposed
groups.
As
result,
SFA,
MUFA
PUFA
affected
DEHT-exposed
Also,
varied
DEHT100-group.
Considering
physiological
responses,
both
groups
lost
return
original
digestive
gland
(DG)
cells.
On
other
hand,
gills
DG
by
exposure.
Overall,
showed
first
time
that
differentially
affect
mussels,
lipid
metabolism,
well
cellular
parameters.
