European Journal of Medicinal Chemistry Reports,
Год журнала:
2024,
Номер
12, С. 100199 - 100199
Опубликована: Авг. 10, 2024
Calendula,
commonly
known
as
marigold,
is
a
plant
of
the
Asteraceae
family
with
rich
history
medicinal
use.
This
possesses
variety
bioactive
compounds,
including
steroids,
terpenoids,
triterpenoids,
phenolic
acids,
flavonoids,
carotenoids,
and
essential
oils.
These
compounds
confer
significant
anti-inflammatory,
antioxidant,
antimicrobial,
anticancer
properties
to
making
it
promising
candidate
for
treating
various
skin
conditions,
particularly
wounds.
Calendula
extracts
hold
potential
applications
in
pharmaceutical,
food,
cosmetic
industries.
Notably,
these
can
be
utilized
drug
delivery
systems
natural
biomaterials,
offering
benefits
health
conditions.
review
aims
provide
an
updated
synthesis
medical
pharmacological
uses
focus
on
its
role
wound
healing
systems.
It
addresses
limitations
using
Calendula's
active
insights
future
research
application.
Foods,
Год журнала:
2024,
Номер
13(23), С. 3882 - 3882
Опубликована: Ноя. 30, 2024
Natural
plant
polysaccharides
are
renowned
for
their
broad
spectrum
of
biological
activities,
making
them
invaluable
in
both
the
pharmaceutical
and
food
industries.
Their
safety,
characterized
by
low
toxicity
minimal
side
effects,
coupled
with
potential
therapeutic
properties,
positions
as
crucial
elements
health-related
applications.
The
functional
effectiveness
these
is
deeply
connected
to
structural
attributes,
including
molecular
weight,
monosaccharide
components,
types
glycosidic
bonds.
These
influence
how
interact
gut
microbiota,
potentially
alleviating
various
metabolic
inflammatory
disorders
such
bowel
disease,
diabetes,
liver-associated
pathologies,
obesity,
kidney
diseases.
operate
through
a
range
mechanisms.
They
enhance
formation
short-chain
fatty
acids,
which
pivotal
keeping
intestinal
health
balance.
Additionally,
they
strengthen
mucosal
barrier,
deterring
ingress
pathogens
toxins
into
host
system.
By
modulating
immune
responses
within
gut,
help
managing
immune-mediated
disorders,
role
activating
specific
cellular
signaling
pathways
further
underscores
potential.
review
delves
intricate
structure-activity
relationships
natural
interactions
flora.
understanding
relationships,
scientific
community
can
develop
targeted
strategies
use
therapeutics,
leading
innovative
treatments
Furthermore,
insights
gained
drive
advancement
research
polysaccharide
applications,
providing
direction
novel
dietary
supplements
foods
designed
support
overall
well-being.
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Янв. 28, 2025
Polysaccharides
are
recognized
for
their
extensive
biological
functions,
holding
significant
promise
applications
in
both
medicine
and
food
industries.
However,
utilization
is
frequently
constrained
by
challenges
such
as
high
molecular
weights
indistinct
sugar
chain
structures.
Recently,
two
novel
bacterial
strains,
N6T
J3T,
were
isolated
from
the
Nakdong
River
Korea.
These
which
belong
to
phylum
Bacteroidota,
Gram-stain-negative,
non-motile,
aerobic,
rod-shaped
bacteria
have
shown
polysaccharide-degrading
capabilities.
Through
comprehensive
analyses,
including
16S
rRNA
gene
sequencing,
whole-genome
detailed
morphological,
physiological,
chemotaxonomic
characterizations,
these
strains
been
identified
new
species
within
genus
Flavobacterium.
KEGG
pathway
analysis
further
confirmed
robust
capabilities
carbohydrate
utilization.
Additional
investigations
using
dbCAN
dbCAN-PUL
databases
presence
of
carbohydrate-hydrolyzing
enzymes
(CAZymes)
polysaccharide
loci
(PULs)
suggesting
potential
degrade
various
polysaccharides.
Subsequent
vitro
growth
experiments
demonstrated
that
J3T
can
chitin,
β-glucan,
κ-carrageenan,
cellulose.
Given
diverse
degradation
abilities,
formally
proposed
be
named
Flavobacterium
polysaccharolyticum
sp.
nov.
aureirubrum
The
type
designated
(=
KCTC
102173T
=
GDMCC
1.4609T)
102172T
1.4608T),
respectively.
Polymers,
Год журнала:
2025,
Номер
17(3), С. 425 - 425
Опубликована: Фев. 6, 2025
Silk
fibroin
(SF)-based
hydrogels
were
prepared
by
the
simple
evaporation
method.
The
outcomes
of
SF-based
assessed
for
consideration
in
terms
practical
and
convenient
use.
Guar
gum
(GG)
sodium
benzoate
(SB)
are
blending
reagents
to
SF
solution
poured
into
petri
dish
make
hydrogels.
After
leaving
mixture
three
days
solidify,
all
peeled
off
characterized.
SF-blend
guar
(SF-GG)
SF-GG-blend
(SF-GG-SB)
could
be
constructed,
but
different
textures
levels
transparency.
SB
affected
solid
texture
resulted
a
higher
water
contact
angle
(WCA)
value
hydrogel
than
SF-GG.
results
from
Fourier
transform
infrared
spectroscopy
(FTIR)
indicated
main
functional
groups
substances
that
contained
Moreover,
some
interactions
between
also
detected.
A
thermogravimetric
analyzer
(TGA)
was
used
determine
decomposition
as
function
temperature.
DTG
thermograms,
which
exhibit
maximum
temperature,
revealed
interaction
forces
SF,
well
their
structure,
reason
thermal
stability
SF-GG-SB
have
tensile
strength
SF-GG
In
conclusion,
appearance,
texture,
hydrophilicity,
stability,
types
concentrations
substances.
This
suggests
properties
designed
adjusted
attain
desirable
fitting
target
applications.
