Journal of Nanobiotechnology,
Год журнала:
2025,
Номер
23(1)
Опубликована: Март 5, 2025
Photoacoustic
brain
imaging
(PABI)
has
emerged
as
a
promising
biomedical
modality,
combining
high
contrast
of
optical
with
deep
tissue
penetration
ultrasound
imaging.
This
review
explores
the
application
photoacoustic
in
tumor
imaging,
highlighting
synergy
between
nanomaterials
and
state
art
techniques
to
achieve
high-resolution
deeper
tissues.
PABI
leverages
effect,
where
absorbed
light
energy
causes
thermoelastic
expansion,
generating
waves
that
are
detected
converted
into
images.
technique
enables
precise
diagnosis,
therapy
monitoring,
enhanced
clinical
screening,
specifically
management
complex
diseases
such
breast
cancer,
lymphatic
disorder,
neurological
conditions.
Despite
integration
agents
radiation,
providing
comprehensive
overview
current
methodologies,
major
obstacles
treatment,
future
directions
for
improving
diagnostic
therapeutic
outcomes.
The
underscores
significance
robust
research
tool
medical
method,
potential
revolutionize
disease
diagnosis
treatment.
Abstract
Skin
cancer
is
a
global
threat
to
the
healthcare
system
and
estimated
incline
tremendously
in
next
20
years,
if
not
diagnosed
at
an
early
stage.
Even
though
it
curable
stage,
novel
drug
identification,
clinical
success,
resistance
another
major
challenge.
To
bridge
gap
bring
effective
treatment,
important
understand
etiology
of
skin
carcinoma,
mechanism
cell
proliferation,
factors
affecting
growth,
resistance.
The
current
article
focusses
on
understanding
structural
diversity
cancers,
treatments
available
till
date
including
phytocompounds,
chemotherapy,
radiotherapy,
photothermal
therapy,
surgery,
combination
molecular
targets
associated
with
growth
metastasis,
special
emphasis
nanotechnology-based
approaches
for
downregulating
deleterious
disease.
A
detailed
analysis
respect
types
nanoparticles
their
scope
overcoming
multidrug
as
well
trials
has
been
discussed.
Graphical
Photodiagnosis and Photodynamic Therapy,
Год журнала:
2024,
Номер
45, С. 103959 - 103959
Опубликована: Янв. 21, 2024
Breast
cancer
(BC)
remains
an
enigmatic
fatal
modality
ubiquitously
prevalent
in
different
parts
of
the
world.
Contemporary
medicines
face
severe
challenges
remediating
and
healing
breast
cancer.
Due
to
its
spatial
specificity
nominal
invasive
therapeutic
regime,
photothermal
therapy
(PTT)
has
attracted
much
scientific
attention
down
lane.
PTT
utilizes
a
near-infrared
(NIR)
light
source
irradiate
tumor
target
intravenously
or
non-invasively,
which
is
converted
into
heat
energy
over
optical
fibre.
Dynamic
progress
nanomaterial
synthesis
was
achieved
with
specialized
visual,
physicochemical,
biological,
pharmacological
features
make
up
for
inadequacies
expand
horizon
PTT.
Numerous
nanomaterials
have
substantial
NIR
absorption
can
function
as
efficient
transducers.
It
achievable
limit
wavelength
range
absorbance
peak
specific
by
manipulating
their
synthesis,
enhancing
precision
quality
Along
same
lines,
various
are
conjugated
wide
surface-modifying
chemicals,
including
polymers
antibodies,
may
modify
persistence
diminish
toxicity
concerns.
In
this
article,
we
tend
put
forth
insights
fundamental
conceptualizations
on
pre-existing
advances
upon
conjugation
biocompatible
working
synergy
combat
cancer,
encompassing
several
strategies
like
immunotherapy,
chemotherapy,
photodynamic
therapy,
radiotherapy
coupled
Additionally,
role
mechanisms
nanoparticles,
well
possible
alternatives
PTT,
summarized
distinctive
integral
aspect
article.
Journal of Nanobiotechnology,
Год журнала:
2024,
Номер
22(1)
Опубликована: Июль 19, 2024
Abstract
Colorectal
cancer,
the
third
most
prevalent
cancer
globally,
contributes
significantly
to
mortality
rates,
with
over
1.9
million
reported
cases
and
nearly
935,000
fatalities
annually.
Surgical
resection
is
a
primary
approach
for
localized
colorectal
tumors,
adjunct
therapies
like
chemotherapy,
radiotherapy,
targeted/immunotherapy
considered
depending
on
tumor
stage.
However,
despite
preferences
targeted
immunotherapy
post-surgery,
chemotherapy
remains
commonly
chosen
due
its
lower
cost
high
cancer-killing
efficiency.
Yet,
faces
issues
such
as
resistance
severe
side
effects.
Nanotechnology
has
emerged
in
therapy
by
alleviating
drawbacks
of
current
treatment
approaches.
In
past
few
decades,
inorganic
nanoparticles
have
shown
promise
combating
offering
advantages
conventional
chemotherapy.
Compared
organic
nanoparticles,
exhibit
properties
photosensitivity,
conductivity,
magnetic
allure,
thermal
proficiency,
allowing
them
function
both
drug
carriers
therapeutic
agents.
Derived
primarily
from
carbon,
silica,
metals,
metal
oxides,
they
offer
superior
drug-loading
capacity,
heightened
quantum
yield,
participation
advanced
photothermal
photodynamic
therapies.
This
review
provides
brief
overview
pathophysiology
pivotal
role
therapy,
delivery.
Additionally,
it
discusses
numerous
based
recent
literature.
Graphical
abstract
Pharmaceutics,
Год журнала:
2023,
Номер
15(9), С. 2361 - 2361
Опубликована: Сен. 21, 2023
Nanoformulations
have
become
increasingly
useful
as
drug
delivery
technologies
in
recent
decades.
As
therapeutics,
oral
administration
is
the
most
common
method,
although
it
not
always
effective
route
because
of
challenges
with
swallowing,
gastrointestinal
discomfort,
low
solubility,
and
poor
absorption.
One
significant
barriers
that
medications
must
overcome
to
exert
a
therapeutic
effect
impact
first
hepatic
transit.
Studies
shown
controlled-release
systems
using
nanoparticles
composed
biodegradable
natural
polymers
significantly
improve
administration,
which
why
these
materials
attracted
attention.
Chitosan
possesses
wide
variety
properties
functions
pharmaceutical
well
healthcare
industries.
Drug
encapsulation
transport
within
body
are
two
its
important
features.
Moreover,
chitosan
can
enhance
efficacy
by
facilitating
interaction
target
cells.
Based
on
physicochemical
properties,
potentially
be
synthesized
into
nanoparticles,
this
review
summarizes
advances
applications
orally
delivered
nanoparticle
interventions.
