One-pot multicomponent reaction: Synthesis, characterization and antibacterial evaluation of novel tri and tetra-substituted imidazoles DOI
Bahgat R. M. Hussein,

Hayam H. Mohammed,

Eman A. Ahmed

и другие.

Synthetic Communications, Год журнала: 2024, Номер unknown, С. 1 - 11

Опубликована: Дек. 30, 2024

Using one-pot multicomponent reactions, two new series of imidazoles (4a–o and 6a–d), were synthesized due to their great biological activity. The first was accomplished by the reaction O-alkyl vanillins 1a–c, ammonium acetate 2, benzil derivatives 3a–e in ethanol, while second obtained reacting 1a, 3a, amino compounds (aniline 5a or acids 5b–d) acetic acid. vitro antibacterial activity novel synthetic assessed against strains gram positive bacteria, such as Bacillus cereus Staphylococcus aureus, negative Pseudomonas aeruginosa Escherichia coli. findings indicated that some evaluated items have promising agents, especially 4d 4e for (+G) bacteria 4c 4f (−G) bacteria.

Язык: Английский

In situ growth of layered double hydroxides on zirconium phosphate for reinforcing anti-corrosion and wear resistance of waterborne epoxy coatings DOI

Ruiqin Guo,

Caiyou Ding,

Yuan Liu

и другие.

Polymer, Год журнала: 2025, Номер unknown, С. 128048 - 128048

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

7

Development of a Multifunctional Antimicrobial Peptide for Marine Antifouling by Theoretical Calculations and Experimental Approaches DOI
Tong Lou,

Xueqiang Zhuang,

Jiangfan Chang

и другие.

ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown

Опубликована: Фев. 15, 2025

Marine biofouling poses significant challenges to the economy, safety, and reliability of marine infrastructure. While antimicrobial peptides (AMPs) have emerged as green efficient antifouling agents, their single functionality complexity preparing surfaces remain key challenges. This study introduces a multifunctional AMP with combined adhesion properties, derived from 3,4-dihydroxy-l-phenylalanine (DOPA) IP12 (sequence IRLRWRWKWPWP). The directional recombination was guided by theoretical calculations. Density functional theory (DFT) simulations identify that hydroxyl groups DOPA were main activating react aluminum alloy. Coarse-grained molecular dynamics (CG MD) all-atom (AA revealed amino acid residues near N-terminal could induce cell membrane bending rupture. fabricated validate accurate calibration performance AMP. Atomic force microscopy, Fourier transform infrared, X-ray photoelectron spectroscopy results confirm successful construction through function. Antifouling evaluations demonstrated properties against Escherichia coli (Gram-negative) Bacillus sp. (Gram-positive), achieving rates 85.8 82.4%, respectively. provides valuable insights into design AMPs.

Язык: Английский

Процитировано

1

Robust Fe3O4@attapulgite-intercalated carboxylated graphene oxide composite membrane for efficient and stable oil-in-water emulsion separation DOI
Pingping Zhang,

Hengyang Mao,

Shouyong Zhou

и другие.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Год журнала: 2025, Номер unknown, С. 136605 - 136605

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Heat Sterilizable Coatings Based on Nafion and Graphene Quantum Dots With Advanced Antibacterial Performance DOI Creative Commons

Mohammed Suleman Beg,

Ella N. Gibbons,

James Duncalf

и другие.

Nano Select, Год журнала: 2025, Номер unknown

Опубликована: Март 31, 2025

ABSTRACT The study focuses on the preparation of electrostatically assembled layer‐by‐layer waterborne nanocoatings comprising negatively charged Nafion and positively imidazole modified‐graphene quantum dots (GQD‐Ims). We demonstrate here that Nafion/GQD‐Im can combat growth representative Gram‐positive Gram‐negative bacteria, their excellent antibacterial performance is preserved after prolonged thermal treatment, indicating coatings withstand dry heat sterilization without any decline in properties. At same time, show remarkable chemical structural stability, while offering protection against UV‐radiation as manifested by dye decomposition experiments. This novel type demonstrates a unique combination highly desirable characteristics, making them ideal candidates for applications related to active packaging cosmetics drugs, food processing, disinfection medical devices.

Язык: Английский

Процитировано

0

Preparation and Properties of Environmentally Friendly Carboxyl Graphene Oxide/Silicone Coatings DOI Open Access
Zhenhua Chu, Jiahao Lu,

Wan Tang

и другие.

Materials, Год журнала: 2025, Номер 18(9), С. 2122 - 2122

Опубликована: Май 5, 2025

To address the protective demands of marine engineering equipment in complex corrosive environments, this study proposes an environmentally friendly composite coating based on carboxylated graphene oxide (CGO)-modified water-based epoxy organosilicon resin. By incorporating varying mass fractions (0.05–0.25%) CGO into resin matrix via mechanical blending, microstructure, corrosion resistance, and long-term kinetics coatings were systematically investigated. The results demonstrate that with 0.15 wt.% (designated as KCG15) exhibited optimal comprehensive performance: its current density (Icorr = 4.37 × 10−8 A/cm2) was two orders magnitude lower than pure coating, while low-frequency impedance modulus (∣Z∣0.1Hz 4.99 106 Ω⋅cm2) is significantly enhanced, accompanied by improved surface compactness. achieved a 97% inhibition rate against sulfate-reducing bacteria (SRB) through synergistic physical disruption electrostatic repulsion mechanisms. Long-term analysis 60-day seawater immersion identified three degradation phases—permeation (0–1 day), blockage (1–4 days), failure (7–60 days)—with structural evolution from microcrack networks to foam-like blistering ultimately reducing 97.8%. Furthermore, 180-day atmospheric exposure test confirms superior weatherability adhesion KCG15 only minor discoloration observed due hydrophobic surface. This work provides theoretical technical foundations for developing anti-corrosion synergize environmental sustainability performance.

Язык: Английский

Процитировано

0

Shape Memory Effects in Polyurethane Nanocomposites—A Holistic Panorama on Features and Technicalities DOI
Ayesha Kausar

Polymer-Plastics Technology and Materials, Год журнала: 2024, Номер unknown, С. 1 - 30

Опубликована: Сен. 16, 2024

Язык: Английский

Процитировано

0

One-pot multicomponent reaction: Synthesis, characterization and antibacterial evaluation of novel tri and tetra-substituted imidazoles DOI
Bahgat R. M. Hussein,

Hayam H. Mohammed,

Eman A. Ahmed

и другие.

Synthetic Communications, Год журнала: 2024, Номер unknown, С. 1 - 11

Опубликована: Дек. 30, 2024

Using one-pot multicomponent reactions, two new series of imidazoles (4a–o and 6a–d), were synthesized due to their great biological activity. The first was accomplished by the reaction O-alkyl vanillins 1a–c, ammonium acetate 2, benzil derivatives 3a–e in ethanol, while second obtained reacting 1a, 3a, amino compounds (aniline 5a or acids 5b–d) acetic acid. vitro antibacterial activity novel synthetic assessed against strains gram positive bacteria, such as Bacillus cereus Staphylococcus aureus, negative Pseudomonas aeruginosa Escherichia coli. findings indicated that some evaluated items have promising agents, especially 4d 4e for (+G) bacteria 4c 4f (−G) bacteria.

Язык: Английский

Процитировано

0