One-pot multicomponent reaction: Synthesis, characterization and antibacterial evaluation of novel tri and tetra-substituted imidazoles DOI
Bahgat R. M. Hussein,

Hayam H. Mohammed,

Eman A. Ahmed

et al.

Synthetic Communications, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 11

Published: Dec. 30, 2024

Using one-pot multicomponent reactions, two new series of imidazoles (4a–o and 6a–d), were synthesized due to their great biological activity. The first was accomplished by the reaction O-alkyl vanillins 1a–c, ammonium acetate 2, benzil derivatives 3a–e in ethanol, while second obtained reacting 1a, 3a, amino compounds (aniline 5a or acids 5b–d) acetic acid. vitro antibacterial activity novel synthetic assessed against strains gram positive bacteria, such as Bacillus cereus Staphylococcus aureus, negative Pseudomonas aeruginosa Escherichia coli. findings indicated that some evaluated items have promising agents, especially 4d 4e for (+G) bacteria 4c 4f (−G) bacteria.

Language: Английский

In situ growth of layered double hydroxides on zirconium phosphate for reinforcing anti-corrosion and wear resistance of waterborne epoxy coatings DOI

Ruiqin Guo,

Caiyou Ding,

Yuan Liu

et al.

Polymer, Journal Year: 2025, Volume and Issue: unknown, P. 128048 - 128048

Published: Jan. 1, 2025

Language: Английский

Citations

6
Development of a Multifunctional Antimicrobial Peptide for Marine Antifouling by Theoretical Calculations and Experimental Approaches DOI
Tong Lou,

Xueqiang Zhuang,

Jiangfan Chang

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 15, 2025

Marine biofouling poses significant challenges to the economy, safety, and reliability of marine infrastructure. While antimicrobial peptides (AMPs) have emerged as green efficient antifouling agents, their single functionality complexity preparing surfaces remain key challenges. This study introduces a multifunctional AMP with combined adhesion properties, derived from 3,4-dihydroxy-l-phenylalanine (DOPA) IP12 (sequence IRLRWRWKWPWP). The directional recombination was guided by theoretical calculations. Density functional theory (DFT) simulations identify that hydroxyl groups DOPA were main activating react aluminum alloy. Coarse-grained molecular dynamics (CG MD) all-atom (AA revealed amino acid residues near N-terminal could induce cell membrane bending rupture. fabricated validate accurate calibration performance AMP. Atomic force microscopy, Fourier transform infrared, X-ray photoelectron spectroscopy results confirm successful construction through function. Antifouling evaluations demonstrated properties against Escherichia coli (Gram-negative) Bacillus sp. (Gram-positive), achieving rates 85.8 82.4%, respectively. provides valuable insights into design AMPs.

Language: Английский

Citations

1
Robust Fe3O4@attapulgite-intercalated carboxylated graphene oxide composite membrane for efficient and stable oil-in-water emulsion separation DOI
Pingping Zhang,

Hengyang Mao,

Shouyong Zhou

et al.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2025, Volume and Issue: unknown, P. 136605 - 136605

Published: March 1, 2025

Language: Английский

Citations

0
Heat Sterilizable Coatings Based on Nafion and Graphene Quantum Dots With Advanced Antibacterial Performance DOI Creative Commons

Mohammed Suleman Beg,

Ella N. Gibbons,

James Duncalf

et al.

Nano Select, Journal Year: 2025, Volume and Issue: unknown

Published: March 31, 2025

ABSTRACT The study focuses on the preparation of electrostatically assembled layer‐by‐layer waterborne nanocoatings comprising negatively charged Nafion and positively imidazole modified‐graphene quantum dots (GQD‐Ims). We demonstrate here that Nafion/GQD‐Im can combat growth representative Gram‐positive Gram‐negative bacteria, their excellent antibacterial performance is preserved after prolonged thermal treatment, indicating coatings withstand dry heat sterilization without any decline in properties. At same time, show remarkable chemical structural stability, while offering protection against UV‐radiation as manifested by dye decomposition experiments. This novel type demonstrates a unique combination highly desirable characteristics, making them ideal candidates for applications related to active packaging cosmetics drugs, food processing, disinfection medical devices.

Language: Английский

Citations

0
Shape Memory Effects in Polyurethane Nanocomposites—A Holistic Panorama on Features and Technicalities DOI
Ayesha Kausar

Polymer-Plastics Technology and Materials, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 30

Published: Sept. 16, 2024

Language: Английский

Citations

0
One-pot multicomponent reaction: Synthesis, characterization and antibacterial evaluation of novel tri and tetra-substituted imidazoles DOI
Bahgat R. M. Hussein,

Hayam H. Mohammed,

Eman A. Ahmed

et al.

Synthetic Communications, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 11

Published: Dec. 30, 2024

Using one-pot multicomponent reactions, two new series of imidazoles (4a–o and 6a–d), were synthesized due to their great biological activity. The first was accomplished by the reaction O-alkyl vanillins 1a–c, ammonium acetate 2, benzil derivatives 3a–e in ethanol, while second obtained reacting 1a, 3a, amino compounds (aniline 5a or acids 5b–d) acetic acid. vitro antibacterial activity novel synthetic assessed against strains gram positive bacteria, such as Bacillus cereus Staphylococcus aureus, negative Pseudomonas aeruginosa Escherichia coli. findings indicated that some evaluated items have promising agents, especially 4d 4e for (+G) bacteria 4c 4f (−G) bacteria.

Language: Английский

Citations

0