Biomaterials and Encapsulation Techniques for Probiotics: Current Status and Future Prospects in Biomedical Applications

Nanomaterials, Год журнала: 2023, Номер 13(15), С. 2185 - 2185

Опубликована: Июль 27, 2023

Probiotics have garnered significant attention in recent years due to their potential advantages diverse biomedical applications, such as acting antimicrobial agents, aiding tissue repair, and treating diseases. These live bacteria must exist appropriate quantities precise locations exert beneficial effects. However, viability activity can be significantly impacted by the surrounding tissue, posing a challenge maintain stability target location for an extended duration. To counter this, researchers formulated various strategies that enhance of probiotics encapsulating them within biomaterials. This approach enables site-specific release, overcoming technical impediments encountered during processing application probiotics. A range materials utilized probiotics, several methods employed this encapsulation process. article reviews advancements encapsulated biomaterials, examining materials, methods, effects encapsulation. It also provides overview hurdles faced currently available biomaterial-based probiotic capsules suggests future research directions field. Despite progress achieved date, numerous challenges persist, necessity developing efficient, reproducible Furthermore, there is need design more robust targeted delivery vehicles.

Язык: Английский

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Development of Gut Microbiota in the First 1000 Days after Birth and Potential Interventions

Nutrients, Год журнала: 2023, Номер 15(16), С. 3647 - 3647

Опубликована: Авг. 20, 2023

The first 1000 days after birth represent a critical window for gut microbiome development, which is essential immune system maturation and overall health. undergoes major changes during this period due to shifts in diet environment. Disruptions the microbiota early life can have lasting health effects, including increased risks of inflammatory disorders, autoimmune diseases, neurological obesity. Maternal environmental factors pregnancy infancy shape infant microbiota. In article, we will review how maintaining healthy important long-term Furthermore, briefly include fungal colonization its effects on host function, are discussed as part ecosystem. Additionally, describe potential approaches such hydrogels enriched with prebiotics probiotics, transplantation (GMT) pregnancy, age-specific microbial ecosystem therapeutics, CRISPR therapies targeting hold advancing research development. Nevertheless, thorough evaluation their safety, effectiveness, impacts crucial prior application clinical approach. article emphasizes need continued optimize development through targeted early-life interventions.

Язык: Английский

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Modification on sodium alginate for food preservation: A review

Trends in Food Science & Technology, Год журнала: 2023, Номер 143, С. 104217 - 104217

Опубликована: Ноя. 5, 2023

Язык: Английский

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Next-Generation Probiotics as Novel Therapeutics for Improving Human Health: Current Trends and Future Perspectives

Microorganisms, Год журнала: 2024, Номер 12(3), С. 430 - 430

Опубликована: Фев. 20, 2024

Next-generation probiotics (NGPs) represent an innovative group of beneficial bacteria that are currently undergoing research and development. NGPs designed not only for conventional use as foods or dietary supplements but also tailored pharmaceutical applications. Research indicates show therapeutic promise in addressing various chronic ailments. Offering multiple advantages over probiotics, present opportunities personalized probiotic therapies, involvement synthetic biology gene editing, participation combination targeted delivery methods, application settings. Our review discusses the potential effect NGPs, covering diverse trajectories including their identification, characterization, delivery. Furthermore, this elucidates influence on critical aspects human health, specifically, gut immune function, broader health outcomes. Mechanistic insights encompass production bioactive compounds, competitive interactions with pathogenic bacteria, modulation cell activity, reinforcement barrier. What is noteworthy current points out prevalent NGP strains sources, providing a highlight comprehensive framework understanding applications future benefits domain advanced therapeutics.

Язык: Английский

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Probiotics in Wound Healing

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(11), С. 5723 - 5723

Опубликована: Май 24, 2024

Wound infections caused by opportunistic bacteria promote persistent infection and represent the main cause of delayed healing. Probiotics are acknowledged for their beneficial effects on human body could be utilized in management various diseases. They also possess capacity to accelerate wound healing, due remarkable anti-pathogenic, antibiofilm, immunomodulatory effects. Oral topical probiotic formulations have shown promising openings field dermatology, there vitro vivo models focusing healing mechanisms. dressings embedded with prebiotics probiotics now prime candidates designing therapeutic approaches combat process. The aim this review is conduct an extensive scientific literature regarding efficacy oral management, as well potential dressing embedding pre- stimulating

Язык: Английский

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Food packaging films from natural polysaccharides and protein hydrogels: A comprehensive review

Food Chemistry X, Год журнала: 2025, Номер 25, С. 102174 - 102174

Опубликована: Янв. 1, 2025

The development of innovative, biodegradable food packaging materials to combat plastic pollution has garnered significant attention from scholars and government agencies worldwide. Natural polysaccharides proteins exhibit excellent modifiability, biodegradability, high ductility, compatibility with products, making them ideal candidates for constructing hydrogels. Hydrogel films based on these biopolymers have opened new research horizons in applications. This review examines natural commonly used hydrogel film preparation explores strategies improve their performance, including the use binary mixtures exogenous additives. To optimize functionality, cross-linking mechanisms between film-forming methods are summarized. Additionally, recent applications discussed, showcasing ability extend or monitor freshness. Despite existing challenges, current advancements present a promising sustainable alternative conventional paving way innovative solutions.

Язык: Английский

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A comprehensive review on the utilization of biopolymer hydrogels to encapsulate and protect probiotics in foods

International Journal of Biological Macromolecules, Год журнала: 2023, Номер 254, С. 127907 - 127907

Опубликована: Ноя. 5, 2023

Язык: Английский

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Probiotic-loaded calcium alginate/fucoidan hydrogels for promoting oral ulcer healing

International Journal of Biological Macromolecules, Год журнала: 2023, Номер 244, С. 125273 - 125273

Опубликована: Июнь 9, 2023

Язык: Английский

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Preparation and synbiotic interaction mechanism of microcapsules of Bifidobacterium animalis F1–7 and human milk oligosaccharides (HMO)

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 259, С. 129152 - 129152

Опубликована: Янв. 2, 2024

Язык: Английский

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Recent developments in encapsulation techniques for innovative and high-quality dairy products: Demands and challenges

Bioactive Carbohydrates and Dietary Fibre, Год журнала: 2024, Номер 31, С. 100406 - 100406

Опубликована: Фев. 14, 2024

Язык: Английский

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