Nanoformulations in Pharmaceutical and Biomedical Applications: Green Perspectives

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(11), С. 5842 - 5842

Опубликована: Май 27, 2024

This study provides a brief discussion of the major nanopharmaceuticals formulations as well impact nanotechnology on future pharmaceuticals. Effective and eco-friendly strategies biofabrication are also highlighted. Modern approaches to designing pharmaceutical nanoformulations (e.g., 3D printing, Phyto-Nanotechnology, Biomimetics/Bioinspiration, etc.) outlined. paper discusses need use natural resources for “green” design new with therapeutic efficiency. Nanopharmaceuticals research is still in its early stages, preparation nanomaterials must be carefully considered. Therefore, safety long-term effects not overlooked. The testing represents an essential point their further applications. Vegetal scaffolds obtained by decellularizing plant leaves represent valuable, bioinspired model nanopharmaceutical that avoids using animals. Nanoformulations critical various fields, especially pharmacy, medicine, agriculture, material science, due unique properties advantages over conventional allows improved solubility, bioavailability, targeted drug delivery, controlled release, reduced toxicity. have transitioned from experimental stages being vital component clinical practice, significantly improving outcomes medical fields cancer treatment, infectious diseases, neurological disorders, personalized advanced diagnostics. Here key points highlighting importance. significant challenges, opportunities, directions mentioned final section.

Язык: Английский

---

Polysaccharides and proteins-based bionanocomposites for microencapsulation of probiotics to improve stability and viability in the gastrointestinal tract: A review

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 259, С. 129287 - 129287

Опубликована: Янв. 9, 2024

Язык: Английский

---

Nano-encapsulation of probiotics: Need and critical considerations to design new non-dairy probiotic products

Journal of Functional Foods, Год журнала: 2024, Номер 116, С. 106192 - 106192

Опубликована: Май 1, 2024

People worldwide need to improve their health or intention control diseases more naturally through ingredients incorporated into foods and beverages, called functional foods. Functional include probiotic organisms bioactive compounds dairy fermentable foods, whose consumption is recommended for various vulnerable groups linked the stay healthy. The increase in production of containing live probiotics has led development new products, particularly non-dairy type, counteract disadvantages such as low digestibility, allergies, intolerance, increased cholesterol, saturated fatty acids, consumer's food preference, which impacts health. In this sense, continuous matrices application nanotechnological strategies had a significant impact on science, providing nano-encapsulation systems transport, storage, release organisms, preserving properties exert beneficial effects without affecting sensory characteristics product. This paper addresses recent advances strains, pointing out advantages limitations according matrix encapsulation techniques used. Considerations are presented design based nano-systems that allow obtaining quality products with nutritional value high bioavailability, viability, protect from factors pH temperature, stability compounds, decrease adverse interactions between components while acting controlled systems. Additionally, toxicological aspects continue toxicity testing intended be used food, even when dealing raw materials recognized non-toxic, pointed out, considering each nanosystem presents different properties. As research use progresses, it may contribute mitigating environmental damage.

Язык: Английский

---

Application of Encapsulation Strategies for Probiotics: From Individual Loading to Co-Encapsulation

Microorganisms, Год журнала: 2023, Номер 11(12), С. 2896 - 2896

Опубликована: Ноя. 30, 2023

Consumers are increasingly showing a preference for foods whose nutritional and therapeutic value has been enhanced. Probiotics live microorganisms, their existence is associated with number of positive effects in humans, as there many well-documented studies related to gut microbiota balance, the regulation immune system, maintenance intestinal mucosal barrier. Hence, probiotics widely preferred by consumers, causing an increase corresponding food sector. As consequence this preference, industries those involved production strongly interested occurrence food, they have proven beneficial on human health when exist appropriate quantities. Encapsulation technology promising technique that aims preserve integrating them other materials order ensure improve effectiveness. Encapsulated also show increased stability survival various stages processing, storage, gastrointestinal transit. This review focuses applications encapsulation sustainable production, including controlled release mechanisms techniques.

Язык: Английский

---

A review of the current state of probiotic nanoencapsulation and its future prospects in biomedical applications

Biocatalysis and Agricultural Biotechnology, Год журнала: 2024, Номер 57, С. 103101 - 103101

Опубликована: Март 14, 2024

Язык: Английский

---

Skin Deep: The Potential of Microbiome Cosmetics

The Journal of Microbiology, Год журнала: 2024, Номер 62(3), С. 181 - 199

Опубликована: Март 1, 2024

Язык: Английский

---

Chitosan and its derivatives: A novel approach to gut microbiota modulation and immune system enhancement

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 289, С. 138633 - 138633

Опубликована: Дек. 13, 2024

Язык: Английский

---

The potential of nanoencapsulated probiotics in the modulation of the gut microbiome

Nanomedicine, Год журнала: 2025, Номер unknown, С. 1 - 4

Опубликована: Янв. 13, 2025

Язык: Английский

---

Harnessing the dual nature of Bacillus (Weizmannia) coagulans for sustainable production of biomaterials and development of functional food

Microbial Biotechnology, Год журнала: 2024, Номер 17(4)

Опубликована: Апрель 1, 2024

Bacillus coagulans, recently renamed Weizmannia is a spore-forming bacterium that has garnered significant interest across various research fields, ranging from health to industrial applications. The probiotic properties of W. coagulans enhance intestinal digestion, by releasing prebiotic molecules including enzymes facilitate the breakdown not-digestible carbohydrates. Notably, some extend beyond digestive functions, serving as valuable biotechnological tools and contributing more sustainable efficient manufacturing processes. Furthermore, homofermentative thermophilic nature renders it an exceptional candidate for fermenting foods lignocellulosic residues into L-(+)-lactic acid. In this review, we provide overview dual in functional development bio-based materials.

Язык: Английский

---

Enhanced probiotic viability in innovative double-network emulsion gels: Synergistic effects of the whey protein concentrate-xanthan gum complex and κ-carrageenan

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 270, С. 131758 - 131758

Опубликована: Май 5, 2024

Язык: Английский

---