Preparation and Efficacy Evaluation of Antihyperuricemic Peptides from Marine Sources DOI Open Access
Kun Qiao, Qianhui Huang,

Tongtong Sun

и другие.

Nutrients, Год журнала: 2024, Номер 16(24), С. 4301 - 4301

Опубликована: Дек. 12, 2024

Marine-derived foods, often called blue are promising sustainable alternatives to conventional food sources owing their abundant amino acids and high protein content. Current treatments for hyperuricemia, a chronic condition attributed purine metabolism disorders, associated with various side effects. Novel peptide xanthine oxidase inhibitors have been discovered in the hydrolyzed products of marine fish invertebrate proteins, which demonstrated therapeutic potential by reducing uric acid levels vitro vivo. This review explores effects derived from invertebrates, summarizes methods extracting bioactive peptides organisms, emphasizes impact different proteases on structure–activity relationship peptides. The hypouricemic these warrant further verification. There is consensus chemical used verify inhibitory Considering several cell animal model development strategies, this highly recognized modeling methods, proposes strategies improve bioavailability peptides, advocates diversified evaluation system. Although screening antihyperuricemic shown be feasible across numerous studies, they not optimal. examines deficiencies bioavailability, synthesis efficiency, mechanisms terms future solutions address issues. provides novel perspective exploration application marine-derived

Язык: Английский

Gut microbiota as a new target for hyperuricemia: A perspective from natural plant products DOI

Ling Dong,

Fengying Dong,

Pingping Guo

и другие.

Phytomedicine, Год журнала: 2025, Номер 138, С. 156402 - 156402

Опубликована: Янв. 18, 2025

Язык: Английский

Процитировано

11

Advancing Pickling Techniques to Enhance Bioactive Compounds and Probiotic Content in Pickled Vegetables DOI
Ahmada Ahmada Kh, Abdullah Abdulaziz Abbod Abdo, Sohail Khan

и другие.

Food Reviews International, Год журнала: 2025, Номер unknown, С. 1 - 27

Опубликована: Март 12, 2025

Язык: Английский

Процитировано

1

Probiotics and bioactive ingredients from fermented foods for the effective prevention and regulation of hyperuricemia DOI
Lei Yuan, Bingxin Zhang, Shuo Wang

и другие.

Current Opinion in Food Science, Год журнала: 2024, Номер 62, С. 101262 - 101262

Опубликована: Дек. 11, 2024

Язык: Английский

Процитировано

3

Effects of Lemongrass Essential Oil on Key Aromas of Pickled Radish During Storage Using HS–GC–IMS and in Silico Approaches DOI Creative Commons
Zelin Li, Ziqi Gao, Chao Li

и другие.

Foods, Год журнала: 2025, Номер 14(5), С. 727 - 727

Опубликована: Фев. 21, 2025

To investigate the effects of lemongrass essential oil on key volatile aroma compounds pickled radish (PR) during storage, this study used headspace–gas chromatography–ion mobility spectrometry, fingerprint analysis, multivariate statistical and molecular docking to different PR samples. The results indicated that a total 48 aromatic were identified. Fingerprint analysis revealed profiles samples at storage stages different. Using screening criteria p < 0.05 variable importance for projection > 1 in relative odor activity value 1, six potential selected. Furthermore, phenylethyl acetate, β-ocimene, 4-heptanone, limonene determined as affect profile after adding oil. Moreover, addition increased fruit sweet storage. recognition these four odors was mainly accomplished through hydrophobic interactions hydrogen bond by OR1A1 OR5M3 receptors. This can offer preliminary foundation theoretical support in-depth exploration paocai industry.

Язык: Английский

Процитировано

0

Preparation, identification and potential mechanism of novel urate-lowering active peptide from hemp protein: From animal model to computer simulation DOI
Mengqi Liu, Hongfu Zhao,

Ziying Zhao

и другие.

Food Research International, Год журнала: 2025, Номер unknown, С. 116643 - 116643

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0

Preparation and Efficacy Evaluation of Antihyperuricemic Peptides from Marine Sources DOI Open Access
Kun Qiao, Qianhui Huang,

Tongtong Sun

и другие.

Nutrients, Год журнала: 2024, Номер 16(24), С. 4301 - 4301

Опубликована: Дек. 12, 2024

Marine-derived foods, often called blue are promising sustainable alternatives to conventional food sources owing their abundant amino acids and high protein content. Current treatments for hyperuricemia, a chronic condition attributed purine metabolism disorders, associated with various side effects. Novel peptide xanthine oxidase inhibitors have been discovered in the hydrolyzed products of marine fish invertebrate proteins, which demonstrated therapeutic potential by reducing uric acid levels vitro vivo. This review explores effects derived from invertebrates, summarizes methods extracting bioactive peptides organisms, emphasizes impact different proteases on structure–activity relationship peptides. The hypouricemic these warrant further verification. There is consensus chemical used verify inhibitory Considering several cell animal model development strategies, this highly recognized modeling methods, proposes strategies improve bioavailability peptides, advocates diversified evaluation system. Although screening antihyperuricemic shown be feasible across numerous studies, they not optimal. examines deficiencies bioavailability, synthesis efficiency, mechanisms terms future solutions address issues. provides novel perspective exploration application marine-derived

Язык: Английский

Процитировано

0