Gut microbiota participates and remodels host metabolism: From treating patients to treating their gut flora

World Journal of Gastroenterology, Год журнала: 2024, Номер 30(45), С. 4839 - 4843

Опубликована: Ноя. 13, 2024

In this editorial, we comment on Liu et al’ s article published in the recent issue of World Journal Gastroenterology . Biochemically and pathologically, al proved that urate-lowering activity leech total protein (LTP) was mainly attributed to rectification gut microbiota. Specifically, noticed change Bacteroides Akkermansia after LTP administration. Both bacteria have been reported alleviate metabolic dysfunction-associated steatohepatitis other chronic diseases. administrated through intragastric manners. Most possibly, would be digested by microbiota further. The anti-hyperuricemia effects should, most possible extent, exerted peptides or their secondary products. Human communicates with organs metabolites generated microbes co-metabolized host. Whether effect could partially ascribed also deserves discussed. Although metabolomics analysis performed for serum samples, fecal highly advocated which facilitate exact mechanism explanation. This study implied contains many unexplored targets different therapeutic potentials. It is foreseeable utilizing these can avoid impairment side directly using human some extent.

Язык: Английский

---

Probiotics and bioactive ingredients from fermented foods for the effective prevention and regulation of hyperuricemia

Current Opinion in Food Science, Год журнала: 2024, Номер 62, С. 101262 - 101262

Опубликована: Дек. 11, 2024

Язык: Английский

---

Ensemble learning based on bi-directional gated recurrent unit and convolutional neural network with word embedding module for bioactive peptide prediction

Food Chemistry, Год журнала: 2024, Номер 468, С. 142464 - 142464

Опубликована: Дек. 12, 2024

Язык: Английский

---

Anti-hyperuricemia effects of a polysaccharide-protein complex from Lentinula edodes mediated by gut-kidney axis

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 293, С. 139370 - 139370

Опубликована: Дек. 30, 2024

Язык: Английский

---