Research progress on the application of aptamer optimization technology and portable sensing devices in food safety detection DOI

Yadi Qin,

Jing Shen, Yanan Qin

и другие.

Critical Reviews in Food Science and Nutrition, Год журнала: 2024, Номер unknown, С. 1 - 33

Опубликована: Дек. 3, 2024

Aptamer-based biosensors with a low cost and high specificity have been widely applied in diagnostics, food safety, environmental monitoring. However, aptamer-based still suffer from insufficient or affinity owing to the inherent constraints of thermodynamic kinetic binding properties aptamers. Therefore, optimization technologies for various aptamers proposed obtain high-affinity constructing high-performance biosensors. In this review, emerging aptamer screening are summarized, followed by focus on analyzing methods optimization, including ligand truncation, mutation, splitting, elongation, chemical modification, potential mechanisms. Portable aptamer-integrated optical electrochemical devices safety point-of-care testing (POCT) platforms reviewed provide reference addressing lack convenience faced aptasensors. Finally, future challenges directions technology discussed further research development detection.

Язык: Английский

Smartphones as a platform for molecular analysis: concepts, methods, devices and future potential DOI Creative Commons
D. G. Baker,

Jasmine Bernal-Escalante,

Christine Traaseth

и другие.

Lab on a Chip, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Smartphones have the potential to transform chemical and biological analysis by functioning as portable, versatile, democratized platforms for molecular diagnostics. Recent advances in optical detection devices are reviewed.

Язык: Английский

Процитировано

0

Microfluidic Paper-Based Devices for Efficient and Sensitive Pesticide Detection: A Review DOI
D. Behera, Kali Prasad Pattanaik, Prabir Kumar Kulabhusan

и другие.

Journal of Food Composition and Analysis, Год журнала: 2025, Номер unknown, С. 107498 - 107498

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Nano-engineered fiber-based sensing frontiers: Revolutionizing on-site pesticide detection for global food-environment nexus challenges DOI
An Du, Hua Li,

Zizhao Guo

и другие.

Coordination Chemistry Reviews, Год журнала: 2025, Номер 538, С. 216710 - 216710

Опубликована: Апрель 18, 2025

Язык: Английский

Процитировано

0

Paper-based analytical device with instrument-free visual signal: A review DOI

Jia Xu,

S. L. Zang,

S. Han

и другие.

Microchemical Journal, Год журнала: 2025, Номер unknown, С. 113741 - 113741

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0

Research progress on the application of aptamer optimization technology and portable sensing devices in food safety detection DOI

Yadi Qin,

Jing Shen, Yanan Qin

и другие.

Critical Reviews in Food Science and Nutrition, Год журнала: 2024, Номер unknown, С. 1 - 33

Опубликована: Дек. 3, 2024

Aptamer-based biosensors with a low cost and high specificity have been widely applied in diagnostics, food safety, environmental monitoring. However, aptamer-based still suffer from insufficient or affinity owing to the inherent constraints of thermodynamic kinetic binding properties aptamers. Therefore, optimization technologies for various aptamers proposed obtain high-affinity constructing high-performance biosensors. In this review, emerging aptamer screening are summarized, followed by focus on analyzing methods optimization, including ligand truncation, mutation, splitting, elongation, chemical modification, potential mechanisms. Portable aptamer-integrated optical electrochemical devices safety point-of-care testing (POCT) platforms reviewed provide reference addressing lack convenience faced aptasensors. Finally, future challenges directions technology discussed further research development detection.

Язык: Английский

Процитировано

0