Research progress on the application of aptamer optimization technology and portable sensing devices in food safety detection DOI

Yadi Qin,

Jing Shen, Yanan Qin

et al.

Critical Reviews in Food Science and Nutrition, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 33

Published: Dec. 3, 2024

Aptamer-based biosensors with a low cost and high specificity have been widely applied in diagnostics, food safety, environmental monitoring. However, aptamer-based still suffer from insufficient or affinity owing to the inherent constraints of thermodynamic kinetic binding properties aptamers. Therefore, optimization technologies for various aptamers proposed obtain high-affinity constructing high-performance biosensors. In this review, emerging aptamer screening are summarized, followed by focus on analyzing methods optimization, including ligand truncation, mutation, splitting, elongation, chemical modification, potential mechanisms. Portable aptamer-integrated optical electrochemical devices safety point-of-care testing (POCT) platforms reviewed provide reference addressing lack convenience faced aptasensors. Finally, future challenges directions technology discussed further research development detection.

Language: Английский

Smartphones as a platform for molecular analysis: concepts, methods, devices and future potential DOI Creative Commons
D. G. Baker,

Jasmine Bernal-Escalante,

Christine Traaseth

et al.

Lab on a Chip, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Smartphones have the potential to transform chemical and biological analysis by functioning as portable, versatile, democratized platforms for molecular diagnostics. Recent advances in optical detection devices are reviewed.

Language: Английский

Citations

0
Microfluidic Paper-Based Devices for Efficient and Sensitive Pesticide Detection: A Review DOI
D. Behera, Kali Prasad Pattanaik, Prabir Kumar Kulabhusan

et al.

Journal of Food Composition and Analysis, Journal Year: 2025, Volume and Issue: unknown, P. 107498 - 107498

Published: March 1, 2025

Language: Английский

Citations

0
Nano-engineered fiber-based sensing frontiers: Revolutionizing on-site pesticide detection for global food-environment nexus challenges DOI
An Du, Hua Li,

Zizhao Guo

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 538, P. 216710 - 216710

Published: April 18, 2025

Language: Английский

Citations

0
Paper-based analytical device with instrument-free visual signal: A review DOI

Jia Xu,

S. L. Zang,

S. Han

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113741 - 113741

Published: April 1, 2025

Language: Английский

Citations

0
Research progress on the application of aptamer optimization technology and portable sensing devices in food safety detection DOI

Yadi Qin,

Jing Shen, Yanan Qin

et al.

Critical Reviews in Food Science and Nutrition, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 33

Published: Dec. 3, 2024

Aptamer-based biosensors with a low cost and high specificity have been widely applied in diagnostics, food safety, environmental monitoring. However, aptamer-based still suffer from insufficient or affinity owing to the inherent constraints of thermodynamic kinetic binding properties aptamers. Therefore, optimization technologies for various aptamers proposed obtain high-affinity constructing high-performance biosensors. In this review, emerging aptamer screening are summarized, followed by focus on analyzing methods optimization, including ligand truncation, mutation, splitting, elongation, chemical modification, potential mechanisms. Portable aptamer-integrated optical electrochemical devices safety point-of-care testing (POCT) platforms reviewed provide reference addressing lack convenience faced aptasensors. Finally, future challenges directions technology discussed further research development detection.

Language: Английский

Citations

0