Unveiling the Therapeutic Potential of Soft Plasma Jet and Nitric-Oxide Enriched Plasma-Activated Water (NO-PAW) on Oral Cancer YD-10B Cells: A Comprehensive Investigation of Direct and Indirect Treatments
Plasma Chemistry and Plasma Processing,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 19, 2025
Язык: Английский
Prunin: An Emerging Anticancer Flavonoid
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(6), С. 2678 - 2678
Опубликована: Март 16, 2025
Despite
the
substantial
advances
in
cancer
therapies,
developing
safe
and
effective
treatment
methodologies
is
critical.
Natural
(plant-derived
compounds),
such
as
flavonoids,
might
be
crucial
a
methodology
without
toxicity
toward
healthy
tissues.
Prunin
flavonoid
with
potential
to
used
biomedical
applications.
has
yet
undergo
thorough
scientific
research,
its
precise
molecular
mechanisms
of
action
remain
largely
unexplored.
This
review
summarizes
therapeutic
prunin
for
first
time,
focusing
on
underlying
an
anticancer
compound.
gained
significant
attention
due
antioxidant,
anti-inflammatory,
effects.
aims
unlock
how
functions
at
level
exert
effects,
primarily
modulating
key
cellular
pathways.
Furthermore,
we
have
discussed
prunin’s
adjunctive
therapy
conventional
treatments,
highlighting
ability
strengthen
responses
while
decreasing
drug
resistance.
Moreover,
discussion
probes
into
innovative
delivery
methods,
particularly
nanoformulations,
that
address
bioavailability,
solubility,
stability
limitations
optimize
application.
By
providing
comprehensive
analysis
properties,
this
stimulate
further
exploration
using
agent,
thereby
progressing
development
targeted,
selective,
safe,
methods.
Язык: Английский
Helium and argon cold plasma effects on the 4T1 cancer cells and a triple negative mouse model of breast cancer
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Март 27, 2025
Nowadays,
cold
atmospheric
plasma
(CAP)
technology
has
developed
as
an
innovative
tool
for
cancer
therapy.
Although
many
studies
have
reported
the
antitumor
effects
of
in
vivo
and
vitro,
there
are
challenges,
including
standardization
devices
treatment
time
different
tumors.
For
first
time,
we
aimed
to
evaluate
compare
optimal
exposure
direction-dependent
cellular
helium
argon
on
4T1
cells
a
triple-negative
mouse
model
breast
cancer.
This
study
used
two
types
jet
with
input
parameters.
In
vitro
evaluations
cell
line
using
MTT
assays
flow
cytometry
analysis
demonstrate
CAP-induced
apoptosis
all
treated
groups,
especially
direct
approach.
These
changes
were
concurrent
increased
intracellular
reactive
oxygen
species
levels
decreased
total
antioxidant
capacity
these
cells.
results
revealed
that
CAP
therapy
reduces
tumor
size,
decreases
Nottingham
histological
score,
prevents
weight
loss,
increases
survival
rate
groups.
suggest
may
overcome
adverse
approved
therapeutic
strategies
seems
be
significant
issue
patients
clinical
stage,
alone
or
combination
current
programs.
Язык: Английский
Study of Sustainability and Health‐Related Living Environment Factors Under the Background of Rural Revitalization in the Towns of Guzhen County
Scientifica,
Год журнала:
2024,
Номер
2024(1)
Опубликована: Янв. 1, 2024
It
is
crucial
to
prioritize
research
and
development
as
part
of
rural
revitalization
efforts
promote
balanced
economic
growth,
preserve
cultural
heritage,
reduce
urban
migration.
This
ensures
sustainability
encourages
equal
access
opportunities,
resources,
a
healthy
environment
for
people
in
both
areas.
For
the
first
time,
this
study
explores
interplay
between
(Factor
A)
health-related
B)
under
background
eight
towns
(Chengguan,
Haocheng,
Liacheng,
Renqiao,
Hugou,
Xinmaqiao,
Liuji,
Wangzhuang)
located
Guzhen
County,
Bengbu
City,
China.
The
County
were
not
studied
these
two
factors
before.
evaluates
environmental
needs
by
gathering
data
from
100
residents
towns,
totaling
800
targeted
area.
Sustainability
highlights
town-specific
priorities;
however,
emphasize
mutual
all
residents.
Similar
results
different
highlight
critical
significance
environment.
Statistical
analysis
reveals
significant
correlation
factors.
stimulates
further
exploration
nuanced
dynamics
revitalization.
A
higher
agreement
percentage
(80%-100%)
on
aspects
underscores
importance
prioritizing
policies
overcome
issues
Язык: Английский