Zinc‐Catalysed [3+2] Cycloaddition of Enaminone with Tosylhydrazide to Synthesise 1H‐pyrazole via C–N and S–N Bond Cleavage DOI
Sanjukta Roy, Rana Chatterjee, Rambabu Dandela

и другие.

Asian Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 14, 2024

Abstract A novel and practical zinc‐catalysed synthesis of 1 H ‐pyrazole has been developed. The one‐pot protocol enables the cycloaddition enaminone tosylhydrazide via C−N S−N bond breaking process, leading to diverse mono‐substituted pyrazole derivatives in high yields. Moreover, easily accessible materials, broad substrate scope with excellent functional group tolerance, ease isolation open‐air conditions are key features present method.

Язык: Английский

Photoelectrochemical upcycling of PVC plastic waste for the synthesis of chlorinated quinolinone derivatives DOI
Kai Zheng, Jingwen He, Zhang Li-xi

и другие.

Organic Chemistry Frontiers, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Herein, an environmentally friendly methodology has been established for the photoelectrochemical chlorination of C(sp 2 )–H bonds in quinolinone derivatives using PVC plastic waste as chlorine source.

Язык: Английский

Процитировано

2

Transition-Metal-Free C–H Trifluoromethylthiolation of N,N-Disubstituted Enaminones To Access CF3S-Functionalized Enaminones and Their Application in the Synthesis of CF3S-Heteroaryls DOI

Jinbiao Ying,

Tao Zhou, Yunyun Liu

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(12), С. 9078 - 9085

Опубликована: Июнь 3, 2024

The α-C–H trifluoromethylthiolation of N,N-disubstituted enaminones has been achieved with simple and cheap CF3SO2Na as the CF3S source. reactions were run at mild temperature (0 °C to rt) using POCl3 only reducing reagent. work represents first example on synthesis α-trifluoromethylthio via direct C–H functionalization. In addition, resulting CF3S-functionalized have proven useful building blocks in various heteroaromatic compounds by annulation reactions.

Язык: Английский

Процитировано

6

Recent advances in multicomponent synthesis of pyrazoles DOI
Jing Zhou,

Quan‐Quan Zhou,

Jie‐Ping Wan

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Pyrazole moiety is considered as an important N-heterocycle in pharmaceuticals and many other functional molecules. The utilization of multicomponent reaction a major tool the current approaches pyrazole synthesis. Considering power significance synthesis, we review herein latest developments this field. According to typical features, contents are divided into reactions with different NN fragment sources, such hydrazine, hydrazone, amidine, nitrile, diazo compounds, ring construction, covering works published since 2019 date.

Язык: Английский

Процитировано

6

Photocatalytic Annulation of Enaminones with Thioureas for the Synthesis of 2-Aminothiazoles via Tandem C–S and C–N Bond Formation DOI
Changfeng Wan, Jie‐Ping Wan,

Qihui Huang

и другие.

Synthesis, Год журнала: 2024, Номер 56(16), С. 2565 - 2571

Опубликована: Апрель 26, 2024

Abstract Visible-light photocatalytic reactions between enaminones and thioureas leading to thiazole products have been achieved. The annulation process consists of tandem C–S C–N bond formation by running under air atmosphere at ambient temperature. Broad substrate tolerance the sustainable protocol has verified practical synthesis divergent thiazoles with both monocyclic fused cyclic structures.

Язык: Английский

Процитировано

5

Electrochemically Enabled Synthesis of Multi-substituted Pyrazoles via a Radical Cyclization Cascade DOI

Wan‐Jie Wei,

Y. M. Zeng,

Xianfeng Liang

и другие.

Green Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

We have developed a mild and efficient electrochemical reduction approach employing aryl diazonium salts as dual synthons to synthesize valuable multi-substituted pyrazoles for the first time.

Язык: Английский

Процитировано

0

Sustainable Synthesis of Pyrazole Derivatives Utilizing Recyclable SnO–CeO2 Nanocomposite as Heterogeneous Catalyst DOI
Amol H. Kategaonkar,

Avinash Aher,

Dnyaneshwar Ghodechor

и другие.

Topics in Catalysis, Год журнала: 2025, Номер unknown

Опубликована: Май 2, 2025

Язык: Английский

Процитировано

0

Electrocatalytic Cleavage of C–C Bonds in Lignin Models Using Nonmetallic Catalysts at Ambient Conditions DOI Creative Commons

Guangyong Liu,

Ziqi Zhai,

Yumiao Lu

и другие.

Chem & Bio Engineering, Год журнала: 2024, Номер 1(4), С. 357 - 365

Опубликована: Фев. 26, 2024

Lignin, characterized by its amorphous, heavily polymerized structure, is a primary natural source of aromatic compounds, yet complex constitution poses considerable challenges in transformation and utilization. Therefore, the selective cleavage C-C bonds represents critical challenging step lignin degradation, essential for production high-value compounds. In this study, we report simple electrocatalytic approach valorization via bond developing nonmetallic electrocatalyst carbon-based materials. It found that hydrophilicity hydrophobicity have significant effect on degradation process. Under mild conditions, hydrophilic carbon paper exhibits 100% substrate conversion, yielding 97% benzaldehyde 96% quinone with ionic liquid electrolytes. The mechanism study shows catalyst higher surface defects favors electron transfer oxidative process bonds. These results signify substantial advancement offering an environmentally friendly, metal-free electrochemical route.

Язык: Английский

Процитировано

2

Electrochemical oxidative selective halogenation of pyrazolones for the synthesis of 4-halopyrazolones DOI

Minghan Li,

Shilin Yang, Jingyi Zhang

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер 22(30), С. 6080 - 6084

Опубликована: Янв. 1, 2024

An efficient and environmentally friendly electrochemical oxidative selective halogenation of pyrazolones has been developed under conditions free metals, external oxidants, supporting electrolytes. The reaction demonstrates good functional group tolerance maintains high efficiency in large-scale synthesis, yielding moderate to excellent yields the desired 4-halopyrazolones. This method provides a green convenient route for direct installation halogen moiety into bioactive pyrazolone derivatives, which can be utilized myriad applications.

Язык: Английский

Процитировано

0

Electrochemical Heterocyclic Ring-Formation Reactions by Making C–N and N–N Bonds DOI
Alexander Sandvoß, J. Winter, Tobias Prenzel

и другие.

Topics in heterocyclic chemistry, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

0

Zinc‐Catalysed [3+2] Cycloaddition of Enaminone with Tosylhydrazide to Synthesise 1H‐pyrazole via C–N and S–N Bond Cleavage DOI
Sanjukta Roy, Rana Chatterjee, Rambabu Dandela

и другие.

Asian Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 14, 2024

Abstract A novel and practical zinc‐catalysed synthesis of 1 H ‐pyrazole has been developed. The one‐pot protocol enables the cycloaddition enaminone tosylhydrazide via C−N S−N bond breaking process, leading to diverse mono‐substituted pyrazole derivatives in high yields. Moreover, easily accessible materials, broad substrate scope with excellent functional group tolerance, ease isolation open‐air conditions are key features present method.

Язык: Английский

Процитировано

0