Toward Spatial Glycomics and Glycoproteomics: Innovations and Applications

BBA Advances, Год журнала: 2025, Номер 7, С. 100146 - 100146

Опубликована: Янв. 1, 2025

Язык: Английский

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Next-Generation Optical Biosensors: Cutting-Edge Advances in Optical Detection Methods

Plasmonics, Год журнала: 2025, Номер unknown

Опубликована: Март 12, 2025

Язык: Английский

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Advancements in Electrochemical Biosensors for Comprehensive Glycosylation Assessment of Biotherapeutics

Sensors, Год журнала: 2025, Номер 25(7), С. 2064 - 2064

Опубликована: Март 26, 2025

Proteins represent a significant portion of the global therapeutics market, surpassing hundreds billions dollars annually. Among various post-translational modifications, glycosylation plays crucial role in influencing protein structure, stability, and function. This modification is especially important biotherapeutics, where precise characterization glycans vital for ensuring product efficacy safety. Although mass spectrometry-based techniques have become essential tools glycomic analysis due to their high sensitivity resolution, complexity lengthy processing times limit practical application. In contrast, electrochemical methods provide rapid, cost-effective, sensitive alternative assessment, enabling real-time glycan structures on biotherapeutic proteins. These techniques, often used conjunction with complementary methods, offer valuable insights into profiles both isolated glycoproteins intact cells. review examines latest advancements biosensors analysis, highlighting potential enhancing biotherapeutics advancing field precision medicine.

Язык: Английский

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Recent Advances in Bioreceptor-based Sensing for Extracellular Vesicle Analysis

Biosensors and Bioelectronics, Год журнала: 2025, Номер unknown, С. 117432 - 117432

Опубликована: Апрель 1, 2025

Язык: Английский

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