Toward Spatial Glycomics and Glycoproteomics: Innovations and Applications

BBA Advances, Journal Year: 2025, Volume and Issue: 7, P. 100146 - 100146

Published: Jan. 1, 2025

Language: Английский

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Next-Generation Optical Biosensors: Cutting-Edge Advances in Optical Detection Methods

Plasmonics, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

Language: Английский

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Advancements in Electrochemical Biosensors for Comprehensive Glycosylation Assessment of Biotherapeutics

Sensors, Journal Year: 2025, Volume and Issue: 25(7), P. 2064 - 2064

Published: March 26, 2025

Proteins represent a significant portion of the global therapeutics market, surpassing hundreds billions dollars annually. Among various post-translational modifications, glycosylation plays crucial role in influencing protein structure, stability, and function. This modification is especially important biotherapeutics, where precise characterization glycans vital for ensuring product efficacy safety. Although mass spectrometry-based techniques have become essential tools glycomic analysis due to their high sensitivity resolution, complexity lengthy processing times limit practical application. In contrast, electrochemical methods provide rapid, cost-effective, sensitive alternative assessment, enabling real-time glycan structures on biotherapeutic proteins. These techniques, often used conjunction with complementary methods, offer valuable insights into profiles both isolated glycoproteins intact cells. review examines latest advancements biosensors analysis, highlighting potential enhancing biotherapeutics advancing field precision medicine.

Language: Английский

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Recent Advances in Bioreceptor-based Sensing for Extracellular Vesicle Analysis

Biosensors and Bioelectronics, Journal Year: 2025, Volume and Issue: unknown, P. 117432 - 117432

Published: April 1, 2025

Language: Английский

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