International Journal of Biological Macromolecules, Год журнала: 2024, Номер 282, С. 136910 - 136910
Опубликована: Окт. 30, 2024
Язык: Английский
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 282, С. 136910 - 136910
Опубликована: Окт. 30, 2024
Язык: Английский
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 259, С. 129252 - 129252
Опубликована: Янв. 8, 2024
Язык: Английский
Процитировано
25Materials & Design, Год журнала: 2024, Номер 238, С. 112655 - 112655
Опубликована: Янв. 11, 2024
With the increasing incidence of bone defects in clinical practice, demand for grafts or substitutes has become more urgent. Polydopamine (PDA)-coated tissue engineering materials offer a promising alternative such cases. PDA coating is characterized by solid formed polymerization dopamine under alkaline and oxygen-containing conditions, which can provide implants good hydrophilicity through active functional groups contained structure. More importantly, strong adhesion an anchor between implant drugs to achieve modification surface enhance regeneration. In this review, different effects derivatives their current research were summarized. The mechanisms underlying promoting regeneration have also discussed detail, providing theoretical basis application PDA. Finally, series PDA-coated promotion repair been summarized discussed. This review provides cutting-edge design ideas PDA-based biomaterials highlights treatment strategies defects.
Язык: Английский
Процитировано
20International Journal of Biological Macromolecules, Год журнала: 2023, Номер 246, С. 125570 - 125570
Опубликована: Июнь 25, 2023
Язык: Английский
Процитировано
29International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142134 - 142134
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
1International Journal of Biological Macromolecules, Год журнала: 2023, Номер 253, С. 127601 - 127601
Опубликована: Окт. 21, 2023
Язык: Английский
Процитировано
13Journal of Polymer Science, Год журнала: 2024, Номер 62(19), С. 4341 - 4359
Опубликована: Фев. 28, 2024
Abstract In recent years, natural substance‐based tissue adhesive hydrogels have been widely studied by researchers because of their practicability and affordability. this review, we summarized the design principles mechanisms for constructing from perspective polyphenols (catechol, dopamine, tannic acid), cationic polymers (chitosan, lysine, antibacterial peptides), polysaccharides other substances. addition, according to morphology size hydrogels, it was divided into macroscopic microscopic hydrogels. Therefore, such as injectable hydrogel patches including microspheres were reviewed. Furthermore, review provided outlook based on present The aimed summarize progress in provide a valuable reference development its applications biomedical field.
Язык: Английский
Процитировано
4APL Bioengineering, Год журнала: 2025, Номер 9(1)
Опубликована: Март 1, 2025
Nonunion fractures present a significant clinical challenge because of their complex microenvironment, which includes poor vascularization, insufficient osteogenesis, infection, and separation fracture ends. The current treatments have certain limitations. Inspired by this phenomenon, sandcastle worms secrete adhesive proteins that bind sand grains, shell fragments, mineral particles, thereby constructing “castles.” In study, we developed an injectable bone cement using methacryloyl chitosan (CSMA) combined with specific concentration oyster nanoparticles (OS-np) to treat nonunion fractures. Oyster shells are composed primarily calcium carbonate, releases ions promote angiogenesis osteogenesis. in vivo results at 8 weeks showed the expression BMP2, RUNX2, VEGF OS-np/CSMA group was increased 5.47, 4.38, 3.54 times, respectively, compared control group, significantly enhancing vascularization repair model. injectability ensures it can adapt well structures sites, providing supportive matrix for new formation. Both vitro osteogenesis experiments demonstrated enhanced models, synergistic effects ion release bioactive properties nanoparticles. This study highlights potential as promising treatment strategy effectively promotes
Язык: Английский
Процитировано
0Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 162182 - 162182
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0International Journal of Biological Macromolecules, Год журнала: 2024, Номер 265, С. 130680 - 130680
Опубликована: Март 8, 2024
Язык: Английский
Процитировано
3Cellulose, Год журнала: 2024, Номер 31(18), С. 11035 - 11050
Опубликована: Окт. 26, 2024
Язык: Английский
Процитировано
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