Wound
healing
is
a
process
in
which
the
body
repairs
and
restores
damaged
or
injured
tissue
to
its
normal
function
structure.
This
complex
dynamic
involves
several
stages
cellular
events.
Supporting
natural
wound
promoting
optimal
requires
providing
proper
care,
including
cleaning
wound,
keeping
it
protected
moist,
managing
underlying
health
conditions,
addressing
any
complications
that
may
arise.
Therefore
essential
develop
bio
patches
with
necessary
properties
[1],
[2].
article
highlights
chitosan's
properties,
making
an
ideal
choice
for
healing.
It
presents
comprehensive
review
of
Chitosan-based
impregnated
herbal
drugs
as
novel
approach
care.
Chitosan,
biopolymer
derived
from
chitin,
possesses
biocompatibility,
biodegradability,
antimicrobial
[15].
Herbal
drugs,
various
species,
are
known
their
anti-inflammatory,
antimicrobial,
antioxidant
effects
[3],
[11].
Silver
nitrate
nanoparticles,
ability
stimulate
cell
proliferation,
have
shown
promise
[9].
Incorporating
these
nanoparticles
into
dressings
coatings
can
promote
faster
closure
reduce
risk
infections.
A
well-designed
patch,
by
regeneration
reducing
inflammation,
help
minimize
formation
excessive
scar
pain
associated
site.
The
protein
extraction
fabrication
such
biopatch
figure
1.
creates
barrier
protects
external
contaminants
promotes
regeneration,
conducive
environment
Biomaterials Science,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 1, 2024
Natural
resource
based
polymers,
especially
those
derived
from
proteins,
have
attracted
significant
attention
for
their
potential
utilization
in
advanced
wound
care
applications.
Protein
materials
provide
superior
biocompatibility,
biodegradability,
and
other
functionalities
compared
to
conventional
dressings.
The
effectiveness
of
various
fabrication
techniques,
such
as
electrospinning,
phase
separation,
self-assembly,
ball
milling,
is
examined
the
context
developing
protein-based
healing.
These
methods
produce
a
wide
range
forms,
including
hydrogels,
scaffolds,
sponges,
films,
bioinspired
nanomaterials,
each
designed
specific
types
wounds
different
stages
This
review
presents
comprehensive
analysis
recent
research
that
investigates
transformation
proteins
into
healing
Our
focus
on
essential
keratin,
collagen,
gelatin,
silk,
zein,
albumin,
we
emphasize
distinct
traits
roles
management.
Protein-based
show
promising
biomedical
engineering,
offering
improved
capabilities
reduced
risks
infection.
It
crucial
explore
use
these
clinical
settings
while
also
addressing
challenges
may
arise
commercialization
future.
Keratin
has
gained
increased
curiosity
from
researchers
in
the
last
decade
for
its
potential
applications
preparation
of
biomaterials.
Most
emphasized
properties
keratin
as
a
candidate
to
manufacture
biomaterials
involves
biodegradability,
excellent
biocompatibility,
self
–
assembling
capability,
ability
support
cell
growth
and
proliferation,
water
absorption
easy
availability
waste.
based
form
fibres,
scaffolds,
films,
hydrogels,
nanoparticles
are
being
explored
various
biomedical
including
wound
healing,
drug
delivery,
oral
tissue
regeneration,
study
models
well
nerve
regeneration.
Methods
opted
fabrication
these
materials
include
electrospinning,
cross-linking
solution
casting
among
others.
In
order
improve
antimicrobial
bioactivity
they
could
also
be
loaded
with
molecules,
antibiotics,
factors
other
functional
peptides.
have
advantage
high
loading
capacity
controlled
prolonged
release
drug,
thus
maximizing
at
target
site.
This
current
paper
critically
reviews
latest
developments
utilization
keratin-based
aforesaid
fields.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Дек. 23, 2024
Abstract
One
of
the
biggest
challenges
in
food
packaging
is
creation
sustainable
and
eco-friendly
materials
to
shield
foods
from
ultraviolet
(UV)
photochemical
damage
preserve
distinctive
physical,
chemical,
biological
characteristics
throughout
supply
chain.
Accordingly,
this
study
focuses
on
enhancing
UV
shielding
properties
activity
carboxylmethyl
cellulose
sodium
(CMC)
through
modifications
using
zinc
oxide
(ZnO),
copper
(CuO),
graphene
(GO)
solution
casting
technique.
The
hybrid
nanocomposites
were
characterized
by
fourier-transform
infrared
(FTIR)
spectrophotometer,
ultraviolet-visible
(UV-Vis)
scanning
electron
microscopy
(SEM),
energy-dispersive
X-ray
spectroscopy
(EDX),
x-ray
diffraction
(XRD).
Significant
interactions
between
CMC
metal
oxide/GO
revealed
FTIR
analysis,
which
reflects
formation
hydrogen
bonding
nanocomposites.
XRD
confirmed
functionalization
with
ZnO/GO
CuO/GO
Additionally,
film
showed
a
decrease
optical
bandgap
5.53
3.43
eV
improved
capacity.
Moreover,
composite
films
had
excellent
refractive
index
conductivity
values
1.97
1.56
×
10
Ω
cm
−
1
,
respectively.
SEM
EDX
analysis
within
matrix.
Thus,
dedicates
that
have
promising
applications
materials.
These
results
quantum
mechanical
calculations
utilizing
density
functional
theory
(DFT).
Total
dipole
moment
(TDM),
frontier
molecular
orbitals
(FMOs),
chemical
reactivity
descriptors,
electrostatic
potential
(MESP)
maps
all
studied
B3LYP/LanL2DZ
model.
TDM
FMO
investigations
CMC/CuO/GO
model
has
highest
(84.031
Debye)
smallest
band
gap
energy
(0.118
eV).
CMC’s
increased
after
integration,
as
demonstrated
MESP
mapping.
Finally,
antibacterial
pure
CMC,
CMC/ZnO/GO,
nanocomposite
was
evaluated
against
Staphylococcus
aureus
Escherichia
coli
.
zones
inhibition
data
both
CMC/ZnO/GO
exhibited
higher
than
alone,
particularly
S.
for
16
mm
14
mm,
respectively,
suggesting
enhanced
susceptibility
compared
E.
highlight
significant
ZnO
CuO
NPs
improving
antimicrobial
efficacy
Wound
healing
is
a
process
in
which
the
body
repairs
and
restores
damaged
or
injured
tissue
to
its
normal
function
structure.
This
complex
dynamic
involves
several
stages
cellular
events.
Supporting
natural
wound
promoting
optimal
requires
providing
proper
care,
including
cleaning
wound,
keeping
it
protected
moist,
managing
underlying
health
conditions,
addressing
any
complications
that
may
arise.
Therefore
essential
develop
bio
patches
with
necessary
properties
[1],
[2].
article
highlights
chitosan's
properties,
making
an
ideal
choice
for
healing.
It
presents
comprehensive
review
of
Chitosan-based
impregnated
herbal
drugs
as
novel
approach
care.
Chitosan,
biopolymer
derived
from
chitin,
possesses
biocompatibility,
biodegradability,
antimicrobial
[15].
Herbal
drugs,
various
species,
are
known
their
anti-inflammatory,
antimicrobial,
antioxidant
effects
[3],
[11].
Silver
nitrate
nanoparticles,
ability
stimulate
cell
proliferation,
have
shown
promise
[9].
Incorporating
these
nanoparticles
into
dressings
coatings
can
promote
faster
closure
reduce
risk
infections.
A
well-designed
patch,
by
regeneration
reducing
inflammation,
help
minimize
formation
excessive
scar
pain
associated
site.
The
protein
extraction
fabrication
such
biopatch
figure
1.
creates
barrier
protects
external
contaminants
promotes
regeneration,
conducive
environment
