Evaluation of biobased materials in the development of polymeric membranes for water capture and purification

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 297, С. 139791 - 139791

Опубликована: Янв. 14, 2025

Язык: Английский

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Effect of different crosslinking agents on carboxymethyl chitosan-glycyrrhizic acid hydrogel: Characterization and biological activities comparison

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 298, С. 139977 - 139977

Опубликована: Янв. 16, 2025

Язык: Английский

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The potential of collagen-based materials for wound management

Materials Today Chemistry, Год журнала: 2024, Номер 41, С. 102295 - 102295

Опубликована: Сен. 13, 2024

Язык: Английский

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Chitosan/alginate polyelectrolyte complex hydrogels by additive manufacturing for in vitro 3D ovarian Cancer modeling

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 139795 - 139795

Опубликована: Янв. 1, 2025

Язык: Английский

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Development of a thiol-maleimide crosslinked carboxymethyl guar gum hydrogel for sustained drug delivery

Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер unknown, С. 106633 - 106633

Опубликована: Янв. 1, 2025

Язык: Английский

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Release Profile and Antibacterial Activity of Thymus sibthorpii Essential Oil-Incorporated, Optimally Stabilized Type I Collagen Hydrogels

Bioengineering, Год журнала: 2025, Номер 12(1), С. 89 - 89

Опубликована: Янв. 19, 2025

Antimicrobial resistance is one of the drastically increasing major global health threats due to misuse and overuse antibiotics as traditional antimicrobial agents, which render urgent need for alternative safer such essential oils (EOs). Although strong activity various EOs has already been studied revealed, their characteristic high sensitivity volatility drives towards a more efficient drug administration method via biomaterial system. Herein, potential Thymus sibthorpii EO incorporated in functionalized antibacterial collagen hydrogels was investigated. At first, optimally stabilized type I six different multi-arm poly (ethylene glycol) succinimidyl glutarate (starPEG) crosslinkers were determined by assessing free amine content enzymatic degradation. Subsequently, 0.5, 1, 2% v/v into optimized hydrogels, release profile, well kinetics, studied. Finally, cytocompatibility tests performed. released from hydrogel matrix Fickian diffusion showed sustained 0.5% EO-loaded adequate against Staphylococcus aureus did not show any statistically significant difference compared penicillin (p < 0.05). Moreover, none fabricated composite scaffolds displayed cytotoxicity on NIH-3T3 fibroblasts. In conclusion, this work presents an innovative system tissue engineering applications, could serve promising antibiotics, contributing coping with issue resistance.

Язык: Английский

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Development of ROS-responsive collagen-based hemostatic sponges for the repair of MRSA-infected wounds

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 140990 - 140990

Опубликована: Фев. 1, 2025

Язык: Английский

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Synthesis of Functional Pectin‐Based Hydrogels via Thiol‐Maleimide Click Reaction for Enhanced Drug Encapsulation and Release

Journal of Applied Polymer Science, Год журнала: 2025, Номер unknown

Опубликована: Фев. 12, 2025

ABSTRACT This work describes the synthesis and characterization of a novel hydrogel system based on pectin (PT) functionalized with thiol maleimide groups cross‐linked by thiol‐maleimide click chemistry. Thiolated PT (PT‐SH) maleimide‐modified (PT‐Ma) precursors were synthesized carbodiimide‐mediated amidation confirmed elemental analysis, FTIR, 1H NMR spectroscopy. The resulting exhibited gelation efficiency over 80%, swelling degrees ranging from 44% to 80% depending cross‐linking density, pH‐sensitive behavior maximum at pH 8. demonstrated high mechanical stability, compressive strengths 20.8–33.2 kPa, increasing density. As model drug, ibuprofen was encapsulated efficiencies up 337 mg/g released in controlled fashion. In vitro release studies showed slower acidic environments, which ranged 22% 53% within 6–10 h, faster slightly alkaline environment, consistent profile hydrogel. Such properties underline hydrogel's potential for sustained drug delivery. Pectin hydrogels, upon cross‐linking, are hereby presented be strong platform biomedical applications properties, behavior, performance

Язык: Английский

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Modification of gelatin hydrogel for soil water retention: Physical blending or chemical combination with humic substance extracted from compost

European Polymer Journal, Год журнала: 2025, Номер unknown, С. 113884 - 113884

Опубликована: Март 1, 2025

Язык: Английский

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Geranium essential oil downregulates virulence genes and mitigates MRSA wound infections through a multifunctional hydrogel

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 310, С. 143197 - 143197

Опубликована: Апрель 17, 2025

Язык: Английский

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