Science, Engineering and Health Studies,
Год журнала:
2024,
Номер
unknown, С. 24010004 - 24010004
Опубликована: Дек. 31, 2024
Gellan
gum
and
collagen
are
two
biomaterials
that
have
been
extensively
studied
for
their
potential
use
in
wound
healing
tissue
engineering
applications.
is
a
biologically
inert
natural
polymer
increasingly
favored
as
biomaterial
to
form
hydrogels.
Collagen,
on
the
other
hand,
major
component
of
extracellular
matrix
widely
used
applications
due
its
biocompatibility
ability
promote
cell
adhesion
proliferation.
In
this
review,
recent
research
will
be
discussed
related
gellan
collagen,
properties,
engineering.
Advanced Functional Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 21, 2025
Abstract
Electrical
stimulation
(ES)
dressings
have
garnered
considerable
attention
owing
to
their
profound
impact
on
chronic
wound
care,
while
the
existing
ES
necessitate
external
power
supply
or
intricate
structures,
posing
potential
safety
risks
and
usage
inconveniences.
Herein,
a
safe,
stable,
simple,
serviceable,
self‐powered
(5S)
dressing
composed
of
an
electrospinning
asymmetric
nanofiber
membrane
with
screen‐printed
electrodes
polyurethane
foam
is
developed.
The
acts
as
due
its
electrical
double‐layer
effect
during
unidirectional
exudate
transfer,
excellent
water
absorption
retention
properties
effectively
manages
exudate.
This
5S
generates
sustained
low‐voltage
direct
current
in
situ
at
site
creates
favorable
microenvironment
for
re‐epithelization.
In
vitro
vivo
studies
indicate
that
this
can
significantly
promote
healing.
Compared
control
group
(on
7th
day),
collagen
deposition
treated
increased
by
15.9%,
capillary
density
90.6%,
epidermal
thickness
228.3%,
resulting
23.6%
enhancement
healing
rate.
Consequently,
presents
highly
sophisticated
effective
therapeutic
approach
accelerating
Biomacromolecules,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 7, 2025
Hemostatic
materials
should
have
efficient
and
rapid
hemostasis,
good
biocompatibility,
nontoxicity.
However,
common
hemostatic
sponges
often
fail
due
to
their
weak
mechanical
strength,
low
slow
hemostasis.
Herein,
we
developed
novel
multifunctional
chitosan/cellulose/tannic
acid
(CS/OMCC/TA)
biocomposite
by
a
freeze-drying
method
without
adding
any
chemical
cross-linking
agents.
The
water
absorption
rate
of
the
sponge
is
as
high
4404%,
blood
5460%.
In
vitro
coagulation
tests
shown
that
ability
CS/OMCC/TA
significantly
better
than
commercial
hemostasis
materials.
DPPH
radical
scavenging
test
antibacterial
experiments
demonstrated
excellent
antioxidant
properties
inhibitory
effects
on
Staphylococcus
aureus
Escherichia
coli.
Animal
showed
could
rapidly
hemostasize
within
185
s
loss
was
107
mg.
These
findings
provide
biocompatible
for
daily
emergency
trauma
treatment
surgical
ACS Applied Bio Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 12, 2025
Multidrug
resistance
(MDR)
infectious
wounds
are
a
major
concern
due
to
drug
resistance,
leading
increased
patient
morbidity.
Lichenysin
(LCN),
lipopeptide
and
biosurfactant
obtained
from
certain
strains
of
Bacillus
licheniformis,
has
demonstrated
an
excellent
antimicrobial
property.
The
present
study
focuses
on
the
fabrication
comprehensive
evaluation
LCN-incorporated
poly(vinyl
alcohol)
(PVA)/polycaprolactone
(PCL)-based
nanofiber
scaffolds
using
electrospinning
technique
as
potential
wound
healing
biomaterial
for
treatment
MDR
in
diabetic
rats.
LCN-loaded
PVA–PCL
were
characterized
their
physicochemical,
antimicrobial,
vitro
cell
line
L-929,
hemocompatibility,
flow
cytometry,
vivo
healing,
enzyme-linked
immuno
sorbent
assay
(ELISA).
Morphological
analysis
via
scanning
electron
microscopy
(SEM)
images
confirmed
smooth
porous
nanofibers
with
diameters
range
200–300
nm.
Fourier
transform
infrared
X-ray
diffraction
(XRD)
results
structural
integrity,
chemical
compatibility,
amorphous
nature
developed
scaffolds.
loaded
LCN
water
retention,
moderate
biodegradability,
sustained
release
up
72
h.
Mechanical
characterization
robust
tensile
strength
conducive
applications.
Antimicrobial
activity
against
Pseudomonas
aeruginosa
(P.
aeruginosa)
Staphylococcus
aureus
(S.
aureus)
showed
substantial
antibacterial
antibiofilm
activity.
In
studies
enhanced
adhesion,
proliferation,
migration,
viability,
signifying
cytocompatibility
these
exceptional
These
findings
indicate
that
LCN-enriched
hold
significant
therapeutic
strategy
rats
through
multifaceted
approach.
Journal of Biomaterials Science Polymer Edition,
Год журнала:
2025,
Номер
unknown, С. 1 - 31
Опубликована: Апрель 17, 2025
Although
the
skin
has
a
high
healing
capacity,
severe
wounds
often
require
external
interventions
to
heal
properly.
Tissue-engineered
wound
dressings
have
indeed
gained
significant
attention
among
various
treatment
strategies
for
healing.
This
study
focuses
on
integration
of
polyvinyl
pyrrolidone
(PVP),
quaternized
chitosan
(QCS),
and
dextran
(DEX)
prepare
ternary
composite
(PVP/QCS/DEX)
as
dressing
hydrogels
with
varying
concentration
PVP
DEX.
A
variety
analytical
methods,
including
infrared
spectroscopy
(FTIR),
scanning
electron
microscopy
(SEM),
contact
angle,
water
vapor
transmission
rate
(WVTR)
were
employed
assess
characteristics
samples.
The
uniform
interconnected
porous
structure
samples
was
confirmed
by
SEM
results.
All
showed
porosity
transition
rate,
demonstrating
their
ability
provide
suitable
moist
environment
efficient
exudate
handling
antibacterial
test
conducted
demonstrated
activity
drug-loaded
hydrogel
Escherichia
coli
Staphylococcus
aureus.
in
vitro
cytotoxicity
evaluation
using
MTT
assay
that
developed
PVP/QCS/DEX
exhibit
satisfactory
cytocompatibility
promote
cell
viability.
results
scratch
indicated
had
promoted
migration
would
improve
accelerate
process.
vivo
tests
sample
revealed
promising
performance.
Therefore,
based
favorable
performance
observed
throughout
analysis,
as-prepared
show
promise
field
dressings.
RSC Advances,
Год журнала:
2024,
Номер
14(34), С. 24910 - 24927
Опубликована: Янв. 1, 2024
We
have
developed
novel
three-dimensional
scaffolds
composed
of
chitosan,
halloysite
nanotubes
and
silver
nanoparticles
with
enhanced
antimicrobial
activity
fibroblast
cell
compatibility
for
their
potential
use
in
wound
dressing
applications.
