International Journal of Biological Macromolecules, Год журнала: 2024, Номер 282, С. 136715 - 136715
Опубликована: Окт. 23, 2024
Язык: Английский
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 282, С. 136715 - 136715
Опубликована: Окт. 23, 2024
Язык: Английский
Molecules, Год журнала: 2025, Номер 30(2), С. 207 - 207
Опубликована: Янв. 7, 2025
The scientific interest in the chemical modification of chitosan to increase its solubility and application has led conjugation with Schiff bases, which are interesting scaffolds endowed diverse biological properties. resultant chitosan-based bases (CSBs) widely studied literature due myriad activities exerted, both catalytic biological, including anticancer, anti-inflammatory, antioxidant, especially antimicrobial ones. Antimicrobial resistance (AMR) is one major public health challenges twenty-first century because it represents a threat prevention treatment growing number bacterial, parasitic, viral, fungal infections that no longer treatable available drugs. Thus, this review, we present brief outline CSBs as well their complexes metals, particular focus on recent regarding effect these captivating derivatives.
Язык: Английский
Процитировано
2Synthetic Communications, Год журнала: 2024, Номер 54(18), С. 1523 - 1550
Опубликована: Авг. 28, 2024
The chemical transformations of substituted chromones 1a–c were examined toward some nucleophiles namely dimedone (R1), 4-hydroxycoumarin (R2) and 4-hydroxy-1-methylquinolin-2(1H)-one (R3). DFT computation at the B3LYP/6-311 G(d,p) level theory was used to perform theoretical computations for produced compounds. HOMO LUMO analyses performed determine electronic charge distribution reactivity molecules. Molecular electrostatic potential (MEP) surface analysis utilized predict molecule's reactive sites. Moreover, studied compounds showed NLO characteristics, where they have first order hyperpolarizability greater than urea. In addition, GIAO method estimate 1H-NMR 13C-NMR shifts; findings compared with experimental values. Testing generated antibacterial anticancer activities revealed varied degrees inhibitory effect. According Lipinski, Veber, Egen rules, these exhibit physicochemical properties.
Язык: Английский
Процитировано
5International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 141833 - 141833
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 162931 - 162931
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0International Journal of Biological Macromolecules, Год журнала: 2024, Номер 282, С. 136715 - 136715
Опубликована: Окт. 23, 2024
Язык: Английский
Процитировано
2