International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 136715 - 136715
Published: Oct. 23, 2024
Language: Английский
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 136715 - 136715
Published: Oct. 23, 2024
Language: Английский
Molecules, Journal Year: 2025, Volume and Issue: 30(2), P. 207 - 207
Published: Jan. 7, 2025
The scientific interest in the chemical modification of chitosan to increase its solubility and application has led conjugation with Schiff bases, which are interesting scaffolds endowed diverse biological properties. resultant chitosan-based bases (CSBs) widely studied literature due myriad activities exerted, both catalytic biological, including anticancer, anti-inflammatory, antioxidant, especially antimicrobial ones. Antimicrobial resistance (AMR) is one major public health challenges twenty-first century because it represents a threat prevention treatment growing number bacterial, parasitic, viral, fungal infections that no longer treatable available drugs. Thus, this review, we present brief outline CSBs as well their complexes metals, particular focus on recent regarding effect these captivating derivatives.
Language: Английский
Citations
2Synthetic Communications, Journal Year: 2024, Volume and Issue: 54(18), P. 1523 - 1550
Published: Aug. 28, 2024
The chemical transformations of substituted chromones 1a–c were examined toward some nucleophiles namely dimedone (R1), 4-hydroxycoumarin (R2) and 4-hydroxy-1-methylquinolin-2(1H)-one (R3). DFT computation at the B3LYP/6-311 G(d,p) level theory was used to perform theoretical computations for produced compounds. HOMO LUMO analyses performed determine electronic charge distribution reactivity molecules. Molecular electrostatic potential (MEP) surface analysis utilized predict molecule's reactive sites. Moreover, studied compounds showed NLO characteristics, where they have first order hyperpolarizability greater than urea. In addition, GIAO method estimate 1H-NMR 13C-NMR shifts; findings compared with experimental values. Testing generated antibacterial anticancer activities revealed varied degrees inhibitory effect. According Lipinski, Veber, Egen rules, these exhibit physicochemical properties.
Language: Английский
Citations
5International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141833 - 141833
Published: March 1, 2025
Language: Английский
Citations
0Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 162931 - 162931
Published: April 1, 2025
Language: Английский
Citations
0International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 136715 - 136715
Published: Oct. 23, 2024
Language: Английский
Citations
2